Browse entries in the PDBbind-CN Database

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Related entries of code: 1yci
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2w0xRCSB PDB    PDBbind349aa, >2W0X_1|Chain... at 100%
2wa3RCSB PDB    PDBbind349aa, >2WA3_1|Chain... at 100%
2wa4RCSB PDB    PDBbind349aa, >2WA4_1|Chain... at 100%
2yc0RCSB PDB    PDBbind352aa, >2YC0_1|Chain... *
2ydeRCSB PDB    PDBbind352aa, >2YDE_1|Chain... at 100%
4ai8RCSB PDB    PDBbind352aa, >4AI8_1|Chain... at 100%
4bioRCSB PDB    PDBbind352aa, >4BIO_1|Chain... at 100%
5op6RCSB PDB    PDBbind351aa, >5OP6_1|Chain... at 100%
5op8RCSB PDB    PDBbind350aa, >5OP8_1|Chain... at 99%
5opcRCSB PDB    PDBbind350aa, >5OPC_1|Chain... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID1yci
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namehypoxia-inducible factor 1 alpha inhibitor
Ligand NameNDF
EC.Number E.C.1.14.11.16
Resolution 2.7(Å)
Affinity (Kd/Ki/IC50)Ki=83uM
Release Year2005
Protein/NA SequenceCheck fasta file
Primary Reference J.Am.Chem.Soc. v127 pp. 7680-1, 2005
Ligand Properties
Formula C11H11NO5
Molecular Weight 237.209
Exact Mass 237.064
No. of atoms 28
No. of bonds 28
Polar Surface Area 103.7
LOGP Value 2.62      (Computed with XLOGP3)
0.27      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q9NWT6  
Entrez Gene IDNCBI Entrez Gene ID: 55662  
ASDInformation of known allosteric effects of PDB entries

 
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