Browse entries in the PDBbind-CN Database

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Related entries of code: 1yw7
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1r58RCSB PDB    PDBbind369aa, >1R58_1|Chain... at 99%
1r5gRCSB PDB    PDBbind369aa, >1R5G_1|Chain... at 99%
1r5hRCSB PDB    PDBbind369aa, >1R5H_1|Chain... at 99%
1yw8RCSB PDB    PDBbind369aa, >1YW8_1|Chain... at 99%
2aduRCSB PDB    PDBbind369aa, >2ADU_1|Chain... at 99%
2ea2RCSB PDB    PDBbind369aa, >2EA2_1|Chain... at 99%
2ea4RCSB PDB    PDBbind369aa, >2EA4_1|Chain... at 99%
2ga2RCSB PDB    PDBbind369aa, >2GA2_1|Chain... at 99%
2oazRCSB PDB    PDBbind369aa, >2OAZ_1|Chain... at 99%
5clsRCSB PDB    PDBbind371aa, >5CLS_1|Chain... at 100%
5d6eRCSB PDB    PDBbind371aa, >5D6E_1|Chain... at 100%
5d6fRCSB PDB    PDBbind371aa, >5D6F_1|Chain... at 100%
5jfrRCSB PDB    PDBbind369aa, >5JFR_1|Chain... at 100%
5ji6RCSB PDB    PDBbind369aa, >5JI6_1|Chain... at 100%
5lywRCSB PDB    PDBbind378aa, >5LYW_1|Chain... *
5lyxRCSB PDB    PDBbind378aa, >5LYX_1|Chain... at 100%
6qefRCSB PDB    PDBbind378aa, >6QEF_1|Chain... at 100%
6qedRCSB PDB    PDBbind378aa, >6QED_1|Chain... at 100%
6qegRCSB PDB    PDBbind378aa, >6QEG_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID1yw7
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namehuman Methionine aminopeptidase-2 (MetAP2)
Ligand NameA41
EC.Number E.C.3.4.11.18
Resolution 1.85(Å)
Affinity (Kd/Ki/IC50)IC50=1.4uM
Release Year2006
Protein/NA SequenceCheck fasta file
Primary Reference (2006) J. Med. Chem., Vol.49, pp.3832-3849
Ligand Properties
Formula C14H13NO4S
Molecular Weight 291.322
Exact Mass 291.057
No. of atoms 33
No. of bonds 34
Polar Surface Area 91.85
LOGP Value 3.97      (Computed with XLOGP3)
3.65      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 3
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P50579  
Entrez Gene IDNCBI Entrez Gene ID: 10988  
ASDInformation of known allosteric effects of PDB entries

 
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