Browse entries in the PDBbind-CN Database

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Related entries of code: 2c0o
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2hk5RCSB PDB    PDBbind270aa, >2HK5_1|Chain... at 99%
3vryRCSB PDB    PDBbind454aa, >3VRY_1|Chains... at 100%
3vs3RCSB PDB    PDBbind454aa, >3VS3_1|Chains... at 100%
5h09RCSB PDB    PDBbind454aa, >5H09_1|Chain... at 100%
5h0bRCSB PDB    PDBbind454aa, >5H0B_1|Chain... at 100%
5h0eRCSB PDB    PDBbind454aa, >5H0E_1|Chain... at 100%
5h0gRCSB PDB    PDBbind454aa, >5H0G_1|Chain... at 100%
5h0hRCSB PDB    PDBbind454aa, >5H0H_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2c0o
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Nametyrosine-protein kinase hck
Ligand NameL2G
EC.Number E.C.
Resolution 2.85(Å)
Affinity (Kd/Ki/IC50)IC50=1.22uM
Release Year2006
Protein/NA SequenceCheck fasta file
Primary Reference Bioorg.Med.Chem.Lett.v16;pp.118
Ligand Properties
Formula C34H40N9O3
Molecular Weight 622.740
Exact Mass 622.325
No. of atoms 86
No. of bonds 92
Polar Surface Area 137.63
LOGP Value 3.26      (Computed with XLOGP3)
5.22      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 12
No. of Rings: 7
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P08631  
Entrez Gene IDNCBI Entrez Gene ID: 3055  
ASDInformation of known allosteric effects of PDB entries

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