Browse entries in the PDBbind-CN Database

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Related entries of code: 2p3g
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2jboRCSB PDB    PDBbind326aa, >2JBO_1|Chain... at 99%
2jbpRCSB PDB    PDBbind326aa, >2JBP_1|Chains... at 99%
2pzyRCSB PDB    PDBbind324aa, >2PZY_1|Chains... at 100%
3a2cRCSB PDB    PDBbind324aa, >3A2C_1|Chains... at 100%
3fpmRCSB PDB    PDBbind325aa, >3FPM_1|Chain... at 99%
3fyjRCSB PDB    PDBbind327aa, >3FYJ_1|Chain... at 100%
3fykRCSB PDB    PDBbind327aa, >3FYK_1|Chain... at 100%
3kc3RCSB PDB    PDBbind324aa, >3KC3_1|Chains... at 100%
3r2bRCSB PDB    PDBbind318aa, >3R2B_1|Chains... at 100%
3r2yRCSB PDB    PDBbind319aa, >3R2Y_1|Chain... at 100%
3wi6RCSB PDB    PDBbind324aa, >3WI6_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3fxwRCSB PDB    PDBbindF10

Entry Information
PDB ID2p3g
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMAP kinase-activated protein kinase 2
Ligand NameF10
EC.Number E.C.2.7.11.1
Resolution 3.8(Å)
Affinity (Kd/Ki/IC50)IC50=0.126uM
Release Year2007
Protein/NA SequenceCheck fasta file
Primary Reference J.Med.Chem. 50: 2647-2654
Ligand Properties
Formula C18H14FN3O
Molecular Weight 307.322
Exact Mass 307.112
No. of atoms 37
No. of bonds 40
Polar Surface Area 57.78
LOGP Value 2.41      (Computed with XLOGP3)
3.50      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P49137  
Entrez Gene IDNCBI Entrez Gene ID: 9261  
ASDInformation of known allosteric effects of PDB entries

 
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