Browse entries in the PDBbind-CN Database

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Related entries of code: 2qpj
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1dmtRCSB PDB    PDBbind696aa, >1DMT_1|Chain... *
1r1hRCSB PDB    PDBbind696aa, >1R1H_1|Chain... at 100%
1r1iRCSB PDB    PDBbind696aa, >1R1I_1|Chain... at 100%
1r1jRCSB PDB    PDBbind696aa, >1R1J_1|Chain... at 100%
2yb9RCSB PDB    PDBbind696aa, >2YB9_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2qpj
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameNeprilysin
Ligand NameI20
EC.Number E.C.3.4.24.11
Resolution 2.05(Å)
Affinity (Kd/Ki/IC50)IC50=0.45uM
Release Year2007
Protein/NA SequenceCheck fasta file
Primary Reference Acta Crystallogr.,Sect.D 63: 975-981
Ligand Properties
Formula C25H38N5O7P
Molecular Weight 551.572
Exact Mass 551.251
No. of atoms 76
No. of bonds 77
Polar Surface Area 221.29
LOGP Value -2.29      (Computed with XLOGP3)
0.35      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 8
No. of Rotatable Bonds: 15
No. of Nitrogen and Oxygen Atoms: 12
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P08473  
Entrez Gene IDNCBI Entrez Gene ID: 4311  
ASDInformation of known allosteric effects of PDB entries

 
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