Browse entries in the PDBbind-CN Database

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Related entries of code: 2w8y
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1a28RCSB PDB    PDBbind256aa, >1A28_1|Chains... at 100%
1sqnRCSB PDB    PDBbind261aa, >1SQN_1|Chains... at 100%
1sr7RCSB PDB    PDBbind259aa, >1SR7_1|Chains... at 99%
1zucRCSB PDB    PDBbind259aa, >1ZUC_1|Chains... at 99%
3g8oRCSB PDB    PDBbind263aa, >3G8O_1|Chains... *
3hq5RCSB PDB    PDBbind256aa, >3HQ5_1|Chains... at 100%
3kbaRCSB PDB    PDBbind253aa, >3KBA_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
1nhzRCSB PDB    PDBbind486
5uc1RCSB PDB    PDBbind486

Entry Information
PDB ID2w8y
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein Nameprogesterone receptor (PR)
Ligand Name486
EC.Number E.C.-.-.-.-
Resolution 1.8(Å)
Affinity (Kd/Ki/IC50)Ki=0.82nM
Release Year2009
Protein/NA SequenceCheck fasta file
Primary Reference (2009) J.Biol.Chem. Vol. 284: pp. 19572-19579
Ligand Properties
Formula C29H35NO2
Molecular Weight 429.594
Exact Mass 429.267
No. of atoms 67
No. of bonds 71
Polar Surface Area 40.54
LOGP Value 3.77      (Computed with XLOGP3)
5.41      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 3
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P06401  
Entrez Gene IDNCBI Entrez Gene ID: 5241  
ASDInformation of known allosteric effects of PDB entries

 
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