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Related entries of code: 2wqb
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2oo8RCSB PDB    PDBbind317aa, >2OO8_1|Chain... at 99%
2oscRCSB PDB    PDBbind317aa, >2OSC_1|Chain... at 99%
2p4iRCSB PDB    PDBbind317aa, >2P4I_1|Chains... at 99%
6mweRCSB PDB    PDBbind317aa, >6MWE_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2wqb
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameAngiopoietin-1 receptor, the Tie2 kinase domain
Ligand NameQQ1
EC.Number E.C.
Resolution 2.95(Å)
Affinity (Kd/Ki/IC50)IC50=0.54uM
Release Year2009
Protein/NA SequenceCheck fasta file
Primary Reference (2009) Bioorg.Med.Chem.Lett. Vol. 19: pp. 6670
Ligand Properties
Formula C21H22N6S
Molecular Weight 390.505
Exact Mass 390.163
No. of atoms 50
No. of bonds 54
Polar Surface Area 110.75
LOGP Value 4.40      (Computed with XLOGP3)
5.36      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q02763  
Entrez Gene IDNCBI Entrez Gene ID: 7010  
ASDInformation of known allosteric effects of PDB entries

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