Browse entries in the PDBbind-CN Database

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Related entries of code: 2x4z
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4appRCSB PDB    PDBbind296aa, >4APP_1|Chain... at 98%
4njdRCSB PDB    PDBbind296aa, >4NJD_1|Chain... at 98%
4o0vRCSB PDB    PDBbind293aa, >4O0V_1|Chain... at 99%
4o0xRCSB PDB    PDBbind293aa, >4O0X_1|Chain... at 99%
4o0yRCSB PDB    PDBbind293aa, >4O0Y_1|Chain... at 99%
5bmsRCSB PDB    PDBbind293aa, >5BMS_1|Chain... at 99%
5i0bRCSB PDB    PDBbind296aa, >5I0B_1|Chain... at 98%
5veeRCSB PDB    PDBbind319aa, >5VEE_1|Chain... at 100%
5xvaRCSB PDB    PDBbind293aa, >5XVA_1|Chain... at 99%
5xvfRCSB PDB    PDBbind290aa, >5XVF_1|Chain... at 99%
5xvgRCSB PDB    PDBbind293aa, >5XVG_1|Chain... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
4o0rRCSB PDB    PDBbindX4Z

Entry Information
PDB ID2x4z
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Ligand NameX4Z
EC.Number E.C.
Resolution 2.1(Å)
Affinity (Kd/Ki/IC50)Kd=2.7nM
Release Year2010
Protein/NA SequenceCheck fasta file
Primary Reference (2010) Proc.Natl.Acad.Sci.USA Vol. 107: pp. 9446-9451
Ligand Properties
Formula C25H31N8OS
Molecular Weight 491.632
Exact Mass 491.234
No. of atoms 66
No. of bonds 70
Polar Surface Area 131.51
LOGP Value 3.10      (Computed with XLOGP3)
3.51      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O96013  
Entrez Gene IDNCBI Entrez Gene ID: 10298  
ASDInformation of known allosteric effects of PDB entries

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