Browse entries in the PDBbind-CN Database
HEADER LYASE/DNA 16-JUN-10 2XHI TITLE SEPARATION-OF-FUNCTION MUTANTS UNRAVEL THE DUAL REACTION TITLE 2 MODE OF HUMAN 8-OXOGUANINE DNA GLYCOSYLASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: N-GLYCOSYLASE/DNA LYASE; COMPND 3 CHAIN: A; COMPND 4 SYNONYM: 8-OXOGUANINE DNA GLYCOSYLASE, DNA-(APURINIC OR COMPND 5 APYRIMIDINIC SITE) LYASE, AP LYASE; COMPND 6 EC: 3.2.2.-, 4.2.99.18; COMPND 7 ENGINEERED: YES; COMPND 8 MUTATION: YES; COMPND 9 MOL_ID: 2; COMPND 10 MOLECULE: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'; COMPND 11 CHAIN: B; COMPND 12 MOL_ID: 3; COMPND 13 MOLECULE: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3'; COMPND 14 CHAIN: C SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: BL21(DE3); SOURCE 8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 9 EXPRESSION_SYSTEM_VECTOR: PETDUET1; SOURCE 10 MOL_ID: 2; SOURCE 11 SYNTHETIC: YES; SOURCE 12 MOL_ID: 3; SOURCE 13 SYNTHETIC: YES KEYWDS LYASE-DNA COMPLEX, LYASE/DNA COMPLEX, SEPARATION-OF-FUNCTION MUTANT, KEYWDS 2 HELIX-HAIRPIN-HELIX, DNA REPAIR EXPDTA X-RAY DIFFRACTION AUTHOR B.DALHUS,M.FORSBRING,I.H.HELLE,E.S.VIK,R.J.FORSTROM,P.H.BACKE, AUTHOR 2 I.ALSETH,M.BJORAS REVDAT 2 10-SEP-14 2XHI 1 REMARK VERSN SEQADV REVDAT 1 26-JAN-11 2XHI 0 JRNL AUTH B.DALHUS,M.FORSBRING,I.H.HELLE,E.S.VIK,R.J.FORSTROM, JRNL AUTH 2 P.H.BACKE,I.ALSETH,M.BJORAS JRNL TITL SEPARATION-OF-FUNCTION MUTANTS UNRAVEL THE DUAL- REACTION JRNL TITL 2 MODE OF HUMAN 8-OXOGUANINE DNA GLYCOSYLASE. JRNL REF STRUCTURE V. 19 117 2011 JRNL REFN ISSN 0969-2126 JRNL PMID 21220122 JRNL DOI 10.1016/J.STR.2010.09.023 REMARK 2 REMARK 2 RESOLUTION. 1.55 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.5.0102 REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.55 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 24.63 REMARK 3 DATA CUTOFF (SIGMA(F)) : NONE REMARK 3 COMPLETENESS FOR RANGE (%) : 98.58 REMARK 3 NUMBER OF REFLECTIONS : 73237 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.23113 REMARK 3 R VALUE (WORKING SET) : 0.22935 REMARK 3 FREE R VALUE : 0.26472 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.0 REMARK 3 FREE R VALUE TEST SET COUNT : 3880 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 1.550 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 1.590 REMARK 3 REFLECTION IN BIN (WORKING SET) : 5330 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 99.10 REMARK 3 BIN R VALUE (WORKING SET) : 0.344 REMARK 3 BIN FREE R VALUE SET COUNT : 268 REMARK 3 BIN FREE R VALUE : 0.368 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 2518 REMARK 3 NUCLEIC ACID ATOMS : 575 REMARK 3 HETEROGEN ATOMS : 2 REMARK 3 SOLVENT ATOMS : 399 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 21.9 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 28.746 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 0.00 REMARK 3 B22 (A**2) : 0.00 REMARK 3 B33 (A**2) : 0.00 REMARK 3 B12 (A**2) : 0.00 REMARK 3 B13 (A**2) : 0.00 REMARK 3 B23 (A**2) : 0.00 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.088 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.091 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.066 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 1.827 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.949 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.931 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 3207 ; 0.025 ; 0.021 REMARK 3 BOND LENGTHS OTHERS (A): NULL ; NULL ; NULL REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 4474 ; 2.291 ; 2.169 REMARK 3 BOND ANGLES OTHERS (DEGREES): NULL ; NULL ; NULL REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 311 ; 6.264 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 124 ;33.667 ;22.984 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 409 ;15.539 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 22 ;18.984 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 484 ; 0.163 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 2284 ; 0.014 ; 0.021 REMARK 3 GENERAL PLANES OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 1562 ; 1.510 ; 1.500 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 2508 ; 2.419 ; 2.000 REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 1645 ; 3.044 ; 3.000 REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): 1966 ; 4.393 ; 4.500 REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.40 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE REMARK 3 RIDING POSITIONS. REMARK 4 REMARK 4 2XHI COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 16-JUN-10. REMARK 100 THE PDBE ID CODE IS EBI-41808. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : NULL REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : NULL REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : ESRF REMARK 200 BEAMLINE : ID14-2 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.933 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC REMARK 200 INTENSITY-INTEGRATION SOFTWARE : MOSFLM REMARK 200 DATA SCALING SOFTWARE : SCALA REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 77880 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.55 REMARK 200 RESOLUTION RANGE LOW (A) : 42.40 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 0.0 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 99.5 REMARK 200 DATA REDUNDANCY : 5.8 REMARK 200 R MERGE (I) : NULL REMARK 200 R SYM (I) : 0.06 REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 14.50 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.55 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.63 REMARK 200 COMPLETENESS FOR SHELL (%) : 99.6 REMARK 200 DATA REDUNDANCY IN SHELL : 5.5 REMARK 200 R MERGE FOR SHELL (I) : NULL REMARK 200 R SYM FOR SHELL (I) : 0.58 REMARK 200 <I/SIGMA(I)> FOR SHELL : 2.30 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: MOLREP REMARK 200 STARTING MODEL: PDB ENTRY 1YQR REMARK 200 REMARK 200 REMARK: NONE REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 53 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.6 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: NULL REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 65 2 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -Y,X-Y,Z+2/3 REMARK 290 3555 -X+Y,-X,Z+1/3 REMARK 290 4555 -X,-Y,Z+1/2 REMARK 290 5555 Y,-X+Y,Z+1/6 REMARK 290 6555 X-Y,X,Z+5/6 REMARK 290 7555 Y,X,-Z+2/3 REMARK 290 8555 X-Y,-Y,-Z REMARK 290 9555 -X,-X+Y,-Z+1/3 REMARK 290 10555 -Y,-X,-Z+1/6 REMARK 290 11555 -X+Y,Y,-Z+1/2 REMARK 290 12555 X,X-Y,-Z+5/6 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 2 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 140.65733 REMARK 290 SMTRY1 3 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 3 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 70.32867 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 105.49300 REMARK 290 SMTRY1 5 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 5 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 35.16433 REMARK 290 SMTRY1 6 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 6 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 175.82167 REMARK 290 SMTRY1 7 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 7 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 140.65733 REMARK 290 SMTRY1 8 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 8 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 9 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 9 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 9 0.000000 0.000000 -1.000000 70.32867 REMARK 290 SMTRY1 10 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 10 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 10 0.000000 0.000000 -1.000000 35.16433 REMARK 290 SMTRY1 11 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 11 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 11 0.000000 0.000000 -1.000000 105.49300 REMARK 290 SMTRY1 12 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 12 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 12 0.000000 0.000000 -1.000000 175.82167 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 4110 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 17830 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -38.2 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 400 REMARK 400 COMPOUND REMARK 400 ENGINEERED RESIDUE IN CHAIN A, LYS 249 TO CYS REMARK 400 ENGINEERED RESIDUE IN CHAIN A, CYS 253 TO LYS REMARK 400 ENGINEERED RESIDUE IN CHAIN A, ASP 268 TO ASN REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A -14 REMARK 465 GLY A -13 REMARK 465 SER A -12 REMARK 465 HIS A -11 REMARK 465 HIS A -10 REMARK 465 HIS A -9 REMARK 465 HIS A -8 REMARK 465 HIS A -7 REMARK 465 HIS A -6 REMARK 465 SER A -5 REMARK 465 GLN A -4 REMARK 465 ASP A -3 REMARK 465 PRO A -2 REMARK 465 ASN A -1 REMARK 465 SER A 0 REMARK 465 MET A 1 REMARK 465 PRO A 2 REMARK 465 ALA A 3 REMARK 465 ARG A 4 REMARK 465 ALA A 5 REMARK 465 LEU A 6 REMARK 465 LEU A 7 REMARK 465 PRO A 8 REMARK 465 ARG A 9 REMARK 465 SER A 326 REMARK 465 ARG A 327 REMARK 465 HIS A 328 REMARK 465 ALA A 329 REMARK 465 GLN A 330 REMARK 465 GLU A 331 REMARK 465 PRO A 332 REMARK 465 PRO A 333 REMARK 465 ALA A 334 REMARK 465 LYS A 335 REMARK 465 ARG A 336 REMARK 465 ARG A 337 REMARK 465 LYS A 338 REMARK 465 GLY A 339 REMARK 465 SER A 340 REMARK 465 LYS A 341 REMARK 465 GLY A 342 REMARK 465 PRO A 343 REMARK 465 GLU A 344 REMARK 465 GLY A 345 REMARK 465 DG B 1 REMARK 465 DC C 30 REMARK 475 REMARK 475 ZERO OCCUPANCY RESIDUES REMARK 475 THE FOLLOWING RESIDUES WERE MODELED WITH ZERO OCCUPANCY. REMARK 475 THE LOCATION AND PROPERTIES OF THESE RESIDUES MAY NOT REMARK 475 BE RELIABLE. (M=MODEL NUMBER; RES=RESIDUE NAME; REMARK 475 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE) REMARK 475 M RES C SSEQI REMARK 475 ASP A 81 REMARK 475 LYS A 82 REMARK 475 SER A 83 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 SG CYS A 146 O HOH A 2187 1.54 REMARK 500 O HOH A 2276 O HOH A 2288 1.79 REMARK 500 O HOH A 2202 O HOH A 2205 1.86 REMARK 500 O ASP A 322 O HOH A 2345 1.87 REMARK 500 OP2 DA C 22 O HOH C 2010 1.94 REMARK 500 O HOH A 2199 O HOH A 2201 1.95 REMARK 500 O HOH A 2138 O HOH A 2180 1.97 REMARK 500 O HOH A 2276 O HOH A 2324 2.06 REMARK 500 O HOH A 2190 O HOH C 2012 2.07 REMARK 500 O HOH A 2190 O HOH C 2007 2.07 REMARK 500 O HOH A 2017 O HOH A 2018 2.08 REMARK 500 O HOH A 2147 O HOH A 2149 2.11 REMARK 500 O HOH A 2313 O HOH A 2314 2.12 REMARK 500 C ASP A 322 O HOH A 2345 2.14 REMARK 500 O HOH A 2318 O HOH A 2321 2.18 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 SER A 83 C GLN A 84 N -0.552 REMARK 500 TYR A 99 CE2 TYR A 99 CD2 0.123 REMARK 500 DA B 6 C6 DA B 6 N6 0.051 REMARK 500 DG B 10 O3' DG B 10 C3' -0.040 REMARK 500 DA C 22 N3 DA C 22 C4 0.040 REMARK 500 DT C 25 O4' DT C 25 C1' 0.074 REMARK 500 DT C 25 C5 DT C 25 C7 0.046 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 ARG A 46 NE - CZ - NH2 ANGL. DEV. = -4.3 DEGREES REMARK 500 GLN A 84 C - N - CA ANGL. DEV. = 15.2 DEGREES REMARK 500 LEU A 93 CB - CG - CD1 ANGL. DEV. = 10.2 DEGREES REMARK 500 ARG A 131 NE - CZ - NH1 ANGL. DEV. = 6.3 DEGREES REMARK 500 ARG A 131 NE - CZ - NH2 ANGL. DEV. = -8.9 DEGREES REMARK 500 LEU A 141 CB - CG - CD2 ANGL. DEV. = -10.8 DEGREES REMARK 500 PHE A 144 CB - CG - CD2 ANGL. DEV. = -5.9 DEGREES REMARK 500 ARG A 169 CG - CD - NE ANGL. DEV. = -14.2 DEGREES REMARK 500 ARG A 169 NE - CZ - NH1 ANGL. DEV. = -4.4 DEGREES REMARK 500 ARG A 277 NE - CZ - NH2 ANGL. DEV. = 3.1 DEGREES REMARK 500 DA B 6 C2 - N3 - C4 ANGL. DEV. = 4.6 DEGREES REMARK 500 DA B 6 C5 - C6 - N6 ANGL. DEV. = -5.3 DEGREES REMARK 500 DC B 7 N1 - C2 - O2 ANGL. DEV. = 4.5 DEGREES REMARK 500 DC B 8 O4' - C1' - C2' ANGL. DEV. = 5.5 DEGREES REMARK 500 DC B 8 C6 - N1 - C2 ANGL. DEV. = 3.8 DEGREES REMARK 500 DC B 8 N3 - C4 - C5 ANGL. DEV. = 2.5 DEGREES REMARK 500 DT B 9 O5' - P - OP2 ANGL. DEV. = -6.5 DEGREES REMARK 500 DT B 9 N3 - C2 - O2 ANGL. DEV. = 4.3 DEGREES REMARK 500 DT B 9 N3 - C4 - O4 ANGL. DEV. = 4.0 DEGREES REMARK 500 DT B 9 C5 - C4 - O4 ANGL. DEV. = -5.3 DEGREES REMARK 500 DG B 10 O4' - C1' - N9 ANGL. DEV. = 4.5 DEGREES REMARK 500 DA B 12 O4' - C1' - N9 ANGL. DEV. = -4.4 DEGREES REMARK 500 DC B 13 C3' - C2' - C1' ANGL. DEV. = -7.5 DEGREES REMARK 500 DC B 13 O4' - C1' - N1 ANGL. DEV. = 4.2 DEGREES REMARK 500 DC C 17 O4' - C1' - N1 ANGL. DEV. = 3.8 DEGREES REMARK 500 DC C 21 O5' - C5' - C4' ANGL. DEV. = -5.1 DEGREES REMARK 500 DC C 21 N1 - C2 - O2 ANGL. DEV. = 4.3 DEGREES REMARK 500 DA C 22 C6 - N1 - C2 ANGL. DEV. = 4.2 DEGREES REMARK 500 DA C 22 N1 - C2 - N3 ANGL. DEV. = -4.0 DEGREES REMARK 500 DA C 22 C3' - O3' - P ANGL. DEV. = 10.1 DEGREES REMARK 500 DG C 24 N1 - C2 - N3 ANGL. DEV. = 6.3 DEGREES REMARK 500 DG C 24 C2 - N3 - C4 ANGL. DEV. = -6.6 DEGREES REMARK 500 DG C 24 N3 - C4 - N9 ANGL. DEV. = -3.9 DEGREES REMARK 500 DG C 24 N3 - C2 - N2 ANGL. DEV. = -4.5 DEGREES REMARK 500 DT C 25 O4' - C1' - N1 ANGL. DEV. = -6.1 DEGREES REMARK 500 DT C 25 N1 - C2 - N3 ANGL. DEV. = 6.2 DEGREES REMARK 500 DT C 25 C2 - N3 - C4 ANGL. DEV. = -6.6 DEGREES REMARK 500 DT C 25 C4 - C5 - C6 ANGL. DEV. = 5.1 DEGREES REMARK 500 DT C 25 C6 - C5 - C7 ANGL. DEV. = -4.0 DEGREES REMARK 500 DG C 24 C3' - O3' - P ANGL. DEV. = 9.3 DEGREES REMARK 500 DC C 26 O4' - C1' - N1 ANGL. DEV. = -4.8 DEGREES REMARK 500 DC C 26 N1 - C2 - O2 ANGL. DEV. = 5.2 DEGREES REMARK 500 DC C 26 N3 - C4 - N4 ANGL. DEV. = -5.1 DEGREES REMARK 500 DC C 26 C5 - C4 - N4 ANGL. DEV. = 4.7 DEGREES REMARK 500 DT C 27 O4' - C1' - N1 ANGL. DEV. = 2.8 DEGREES REMARK 500 DA C 28 O4' - C1' - N9 ANGL. DEV. = 3.1 DEGREES REMARK 500 DC C 29 O4' - C1' - N1 ANGL. DEV. = 6.0 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 CYS A 28 104.24 -167.66 REMARK 500 GLN A 43 -65.01 -91.79 REMARK 500 GLN A 84 127.62 -3.82 REMARK 500 LEU A 170 -66.58 -103.98 REMARK 500 ASP A 174 -129.46 52.41 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS REMARK 500 REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES. REMARK 500 MODEL OMEGA REMARK 500 LYS A 82 SER A 83 149.84 REMARK 500 SER A 83 GLN A 84 129.55 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 CA A1327 CA REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 241 O REMARK 620 2 LEU A 243 O 99.6 REMARK 620 3 VAL A 246 O 88.2 83.0 REMARK 620 4 DC C 26 OP2 139.8 118.1 83.3 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 CA C1030 CA REMARK 620 N RES CSSEQI ATOM REMARK 620 1 DG C 24 OP2 REMARK 620 2 ASN A 149 OD1 109.2 REMARK 620 3 HOH C2001 O 115.0 123.4 REMARK 620 N 1 2 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE CA C1030 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE CA A1327 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 2NOF RELATED DB: PDB REMARK 900 STRUCTURE OF Q315F HUMAN 8-OXOGUANINE REMARK 900 GLYCOSYLASE PROXIMALCROSSLINK TO 8-OXOGUANINE DNA REMARK 900 RELATED ID: 2NOE RELATED DB: PDB REMARK 900 STRUCTURE OF CATALYTICALLY INACTIVE G42A HUMAN REMARK 900 8-OXOGUANINEGLYCOSYLASE COMPLEXED TO 8- REMARK 900 OXOGUANINE DNA REMARK 900 RELATED ID: 2I5W RELATED DB: PDB REMARK 900 STRUCTURE OF HOGG1 CROSSLINKED TO DNA REMARK 900 SAMPLING A NORMAL GADJACENT TO AN OXOG REMARK 900 RELATED ID: 1LWV RELATED DB: PDB REMARK 900 BOROHYDRIDE-TRAPPED HOGG1 INTERMEDIATE STRUCTURE REMARK 900 CO-CRYSTALLIZED WITH 8-AMINOGUANINE REMARK 900 RELATED ID: 1N39 RELATED DB: PDB REMARK 900 STRUCTURAL AND BIOCHEMICAL EXPLORATION OF A REMARK 900 CRITICAL AMINOACID IN HUMAN 8-OXOGUANINE REMARK 900 GLYCOSYLASE REMARK 900 RELATED ID: 1FN7 RELATED DB: PDB REMARK 900 COUPLING OF DAMAGE RECOGNITION AND CATALYSIS REMARK 900 BY A HUMANBASE-EXCISION DNA REPAIR PROTEIN REMARK 900 RELATED ID: 2NOL RELATED DB: PDB REMARK 900 STRUCTURE OF CATALYTICALLY INACTIVE HUMAN 8- REMARK 900 OXOGUANINEGLYCOSYLASE DISTAL CROSSLINK TO OXOG REMARK 900 DNA REMARK 900 RELATED ID: 2NOH RELATED DB: PDB REMARK 900 STRUCTURE OF CATALYTICALLY INACTIVE Q315A REMARK 900 HUMAN 8-OXOGUANINE GLYCOSYLASE COMPLEXED TO REMARK 900 8-OXOGUANINE DNA REMARK 900 RELATED ID: 1KO9 RELATED DB: PDB REMARK 900 NATIVE STRUCTURE OF THE HUMAN 8-OXOGUANINE REMARK 900 DNA GLYCOSYLASEHOGG1 REMARK 900 RELATED ID: 2NOB RELATED DB: PDB REMARK 900 STRUCTURE OF CATALYTICALLY INACTIVE H270A REMARK 900 HUMAN 8-OXOGUANINE GLYCOSYLASE CROSSLINKED TO REMARK 900 8-OXOGUANINE DNA REMARK 900 RELATED ID: 1M3H RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF HOGG1 D268E MUTANT WITH REMARK 900 PRODUCTOLIGONUCLEOTIDE REMARK 900 RELATED ID: 1HU0 RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF AN HOGG1-DNA REMARK 900 BOROHYDRIDE TRAPPEDINTERMEDIATE COMPLEX REMARK 900 RELATED ID: 1EBM RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF THE HUMAN 8-OXOGUANINE REMARK 900 GLYCOSYLASE (HOGG1) BOUND TO A SUBSTRATE REMARK 900 OLIGONUCLEOTIDE REMARK 900 RELATED ID: 1N3A RELATED DB: PDB REMARK 900 STRUCTURAL AND BIOCHEMICAL EXPLORATION OF A REMARK 900 CRITICAL AMINOACID IN HUMAN 8-OXOGUANINE REMARK 900 GLYCOSYLASE REMARK 900 RELATED ID: 1M3Q RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF HOGG1 D268E MUTANT WITH REMARK 900 BASE-EXCISEDDNA AND 8-AMINOGUANINE REMARK 900 RELATED ID: 1LWW RELATED DB: PDB REMARK 900 BOROHYDRIDE-TRAPPED HOGG1 INTERMEDIATE STRUCTURE REMARK 900 CO-CRYSTALLIZED WITH 8-BROMOGUANINE REMARK 900 RELATED ID: 1LWY RELATED DB: PDB REMARK 900 HOGG1 BOROHYDRIDE-TRAPPED INTERMEDIATE WITHOUT REMARK 900 8-OXOGUANINE REMARK 900 RELATED ID: 2NOI RELATED DB: PDB REMARK 900 STRUCTURE OF G42A HUMAN 8-OXOGUANINE REMARK 900 GLYCOSYLASECROSSLINKED TO UNDAMAGED G-CONTAINING REMARK 900 DNA REMARK 900 RELATED ID: 2NOZ RELATED DB: PDB REMARK 900 STRUCTURE OF Q315F HUMAN 8-OXOGUANINE REMARK 900 GLYCOSYLASE DISTALCROSSLINK TO 8-OXOGUANINE DNA REMARK 900 RELATED ID: 1N3C RELATED DB: PDB REMARK 900 STRUCTURAL AND BIOCHEMICAL EXPLORATION OF A REMARK 900 CRITICAL AMINOACID IN HUMAN 8-OXOGUANINE REMARK 900 GLYCOSYLASE DBREF 2XHI A 1 345 UNP O15527 OGG1_HUMAN 1 345 DBREF 2XHI B 1 15 PDB 2XHI 2XHI 1 15 DBREF 2XHI C 16 30 PDB 2XHI 2XHI 16 30 SEQADV 2XHI MET A -14 UNP O15527 EXPRESSION TAG SEQADV 2XHI GLY A -13 UNP O15527 EXPRESSION TAG SEQADV 2XHI SER A -12 UNP O15527 EXPRESSION TAG SEQADV 2XHI HIS A -11 UNP O15527 EXPRESSION TAG SEQADV 2XHI HIS A -10 UNP O15527 EXPRESSION TAG SEQADV 2XHI HIS A -9 UNP O15527 EXPRESSION TAG SEQADV 2XHI HIS A -8 UNP O15527 EXPRESSION TAG SEQADV 2XHI HIS A -7 UNP O15527 EXPRESSION TAG SEQADV 2XHI HIS A -6 UNP O15527 EXPRESSION TAG SEQADV 2XHI SER A -5 UNP O15527 EXPRESSION TAG SEQADV 2XHI GLN A -4 UNP O15527 EXPRESSION TAG SEQADV 2XHI ASP A -3 UNP O15527 EXPRESSION TAG SEQADV 2XHI PRO A -2 UNP O15527 EXPRESSION TAG SEQADV 2XHI ASN A -1 UNP O15527 EXPRESSION TAG SEQADV 2XHI SER A 0 UNP O15527 EXPRESSION TAG SEQADV 2XHI CYS A 249 UNP O15527 LYS 249 ENGINEERED MUTATION SEQADV 2XHI LYS A 253 UNP O15527 CYS 253 ENGINEERED MUTATION SEQADV 2XHI ASN A 268 UNP O15527 ASP 268 ENGINEERED MUTATION SEQRES 1 A 360 MET GLY SER HIS HIS HIS HIS HIS HIS SER GLN ASP PRO SEQRES 2 A 360 ASN SER MET PRO ALA ARG ALA LEU LEU PRO ARG ARG MET SEQRES 3 A 360 GLY HIS ARG THR LEU ALA SER THR PRO ALA LEU TRP ALA SEQRES 4 A 360 SER ILE PRO CYS PRO ARG SER GLU LEU ARG LEU ASP LEU SEQRES 5 A 360 VAL LEU PRO SER GLY GLN SER PHE ARG TRP ARG GLU GLN SEQRES 6 A 360 SER PRO ALA HIS TRP SER GLY VAL LEU ALA ASP GLN VAL SEQRES 7 A 360 TRP THR LEU THR GLN THR GLU GLU GLN LEU HIS CYS THR SEQRES 8 A 360 VAL TYR ARG GLY ASP LYS SER GLN ALA SER ARG PRO THR SEQRES 9 A 360 PRO ASP GLU LEU GLU ALA VAL ARG LYS TYR PHE GLN LEU SEQRES 10 A 360 ASP VAL THR LEU ALA GLN LEU TYR HIS HIS TRP GLY SER SEQRES 11 A 360 VAL ASP SER HIS PHE GLN GLU VAL ALA GLN LYS PHE GLN SEQRES 12 A 360 GLY VAL ARG LEU LEU ARG GLN ASP PRO ILE GLU CYS LEU SEQRES 13 A 360 PHE SER PHE ILE CYS SER SER ASN ASN ASN ILE ALA ARG SEQRES 14 A 360 ILE THR GLY MET VAL GLU ARG LEU CYS GLN ALA PHE GLY SEQRES 15 A 360 PRO ARG LEU ILE GLN LEU ASP ASP VAL THR TYR HIS GLY SEQRES 16 A 360 PHE PRO SER LEU GLN ALA LEU ALA GLY PRO GLU VAL GLU SEQRES 17 A 360 ALA HIS LEU ARG LYS LEU GLY LEU GLY TYR ARG ALA ARG SEQRES 18 A 360 TYR VAL SER ALA SER ALA ARG ALA ILE LEU GLU GLU GLN SEQRES 19 A 360 GLY GLY LEU ALA TRP LEU GLN GLN LEU ARG GLU SER SER SEQRES 20 A 360 TYR GLU GLU ALA HIS LYS ALA LEU CYS ILE LEU PRO GLY SEQRES 21 A 360 VAL GLY THR CYS VAL ALA ASP LYS ILE CYS LEU MET ALA SEQRES 22 A 360 LEU ASP LYS PRO GLN ALA VAL PRO VAL ASN VAL HIS MET SEQRES 23 A 360 TRP HIS ILE ALA GLN ARG ASP TYR SER TRP HIS PRO THR SEQRES 24 A 360 THR SER GLN ALA LYS GLY PRO SER PRO GLN THR ASN LYS SEQRES 25 A 360 GLU LEU GLY ASN PHE PHE ARG SER LEU TRP GLY PRO TYR SEQRES 26 A 360 ALA GLY TRP ALA GLN ALA VAL LEU PHE SER ALA ASP LEU SEQRES 27 A 360 ARG GLN SER ARG HIS ALA GLN GLU PRO PRO ALA LYS ARG SEQRES 28 A 360 ARG LYS GLY SER LYS GLY PRO GLU GLY SEQRES 1 B 15 DG DG DT DA DG DA DC DC DT DG DG DA DC SEQRES 2 B 15 DG DC SEQRES 1 C 15 DG DC DG DT DC DC DA 8OG DG DT DC DT DA SEQRES 2 C 15 DC DC MODRES 2XHI 8OG C 23 DG 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE HET 8OG C 23 23 HET CA A1327 1 HET CA C1030 1 HETNAM 8OG 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE HETNAM CA CALCIUM ION HETSYN 8OG 8-OXO-7,8-DIHYDRO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE FORMUL 4 8OG C10 H14 N5 O8 P FORMUL 5 CA 2(CA 2+) FORMUL 6 HOH *399(H2 O) HELIX 1 1 THR A 19 TRP A 23 5 5 HELIX 2 2 ARG A 34 LEU A 39 1 6 HELIX 3 3 THR A 89 PHE A 100 1 12 HELIX 4 4 THR A 105 ASP A 117 1 13 HELIX 5 5 ASP A 117 PHE A 127 1 11 HELIX 6 6 ASP A 136 CYS A 146 1 11 HELIX 7 7 ASN A 151 GLY A 167 1 17 HELIX 8 8 SER A 183 ALA A 188 1 6 HELIX 9 9 GLU A 191 LEU A 199 1 9 HELIX 10 10 TYR A 203 GLU A 218 1 16 HELIX 11 11 GLY A 221 GLN A 227 1 7 HELIX 12 12 LEU A 228 GLU A 230 5 3 HELIX 13 13 SER A 232 CYS A 241 1 10 HELIX 14 14 GLY A 247 LEU A 259 1 13 HELIX 15 15 ASN A 268 SER A 280 1 13 HELIX 16 16 SER A 292 GLY A 308 1 17 HELIX 17 17 TYR A 310 ARG A 324 1 15 SHEET 1 AA 5 ALA A 24 PRO A 27 0 SHEET 2 AA 5 GLN A 72 TYR A 78 -1 O LEU A 73 N ILE A 26 SHEET 3 AA 5 GLN A 62 GLN A 68 -1 O VAL A 63 N TYR A 78 SHEET 4 AA 5 HIS A 54 LEU A 59 -1 O TRP A 55 N LEU A 66 SHEET 5 AA 5 ARG A 48 SER A 51 -1 O ARG A 48 N SER A 56 SHEET 1 AB 2 ARG A 169 LEU A 173 0 SHEET 2 AB 2 VAL A 176 HIS A 179 -1 O VAL A 176 N LEU A 173 LINK CA CA A1327 O CYS A 241 1555 1555 2.59 LINK CA CA A1327 O LEU A 243 1555 1555 2.66 LINK CA CA A1327 O VAL A 246 1555 1555 2.52 LINK CA CA A1327 OP2 DC C 26 1555 1555 2.99 LINK O3' DA C 22 P 8OG C 23 1555 1555 1.62 LINK O3' 8OG C 23 P DG C 24 1555 1555 1.61 LINK CA CA C1030 OD1 ASN A 149 1555 1555 3.16 LINK CA CA C1030 O HOH C2001 1555 1555 2.49 LINK CA CA C1030 OP2 DG C 24 1555 1555 2.81 SITE 1 AC1 4 ASN A 149 DA C 22 DG C 24 HOH C2001 SITE 1 AC2 4 CYS A 241 LEU A 243 VAL A 246 DC C 26 CRYST1 92.669 92.669 210.986 90.00 90.00 120.00 P 65 2 2 12 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.010791 0.006230 0.000000 0.00000 SCALE2 0.000000 0.012460 0.000000 0.00000 SCALE3 0.000000 0.000000 0.004740 0.00000 ATOM 1 N ARG A 10 26.292 -12.844 35.794 1.00 35.51 N ATOM 2 CA ARG A 10 25.212 -12.980 36.817 1.00 34.31 C ATOM 3 C ARG A 10 25.126 -11.750 37.793 1.00 32.34 C ATOM 4 O ARG A 10 24.171 -10.974 37.708 1.00 31.87 O ATOM 5 CB ARG A 10 25.352 -14.316 37.570 1.00 36.55 C ATOM 6 CG ARG A 10 24.221 -14.685 38.525 1.00 39.97 C ATOM 7 CD ARG A 10 23.006 -15.290 37.796 1.00 47.84 C ATOM 8 NE ARG A 10 22.003 -14.242 37.589 1.00 54.26 N ATOM 9 CZ ARG A 10 21.042 -13.948 38.466 1.00 55.76 C ATOM 10 NH1 ARG A 10 20.952 -14.647 39.592 1.00 56.24 N ATOM 11 NH2 ARG A 10 20.171 -12.966 38.218 1.00 55.18 N ATOM 12 N MET A 11 26.058 -11.589 38.731 1.00 28.67 N ATOM 13 CA MET A 11 25.987 -10.427 39.646 1.00 26.23 C ATOM 14 C MET A 11 26.637 -9.171 39.080 1.00 24.54 C ATOM 15 O MET A 11 27.485 -9.240 38.198 1.00 25.89 O ATOM 16 CB MET A 11 26.613 -10.720 41.042 1.00 26.22 C ATOM 17 CG MET A 11 25.936 -11.847 41.896 1.00 24.88 C ATOM 18 SD MET A 11 24.305 -11.559 42.512 1.00 29.78 S ATOM 19 CE MET A 11 23.232 -12.122 41.181 1.00 31.33 C ATOM 20 N GLY A 12 26.236 -8.028 39.593 1.00 21.08 N ATOM 21 CA GLY A 12 26.872 -6.756 39.258 1.00 21.46 C ATOM 22 C GLY A 12 26.221 -6.116 38.044 1.00 19.69 C ATOM 23 O GLY A 12 25.348 -6.708 37.451 1.00 21.64 O ATOM 24 N HIS A 13 26.670 -4.896 37.764 1.00 20.20 N ATOM 25 CA HIS A 13 26.246 -4.171 36.544 1.00 19.97 C ATOM 26 C HIS A 13 26.836 -4.897 35.340 1.00 21.80 C ATOM 27 O HIS A 13 27.971 -5.430 35.397 1.00 24.20 O ATOM 28 CB HIS A 13 26.798 -2.792 36.609 1.00 18.37 C ATOM 29 CG HIS A 13 26.088 -1.905 37.589 1.00 20.02 C ATOM 30 ND1 HIS A 13 26.413 -1.827 38.931 1.00 18.01 N ATOM 31 CD2 HIS A 13 25.071 -1.032 37.396 1.00 18.72 C ATOM 32 CE1 HIS A 13 25.602 -0.972 39.525 1.00 16.21 C ATOM 33 NE2 HIS A 13 24.787 -0.455 38.600 1.00 16.95 N ATOM 34 N ARG A 14 26.020 -5.053 34.307 1.00 20.49 N ATOM 35 CA ARG A 14 26.442 -5.776 33.102 1.00 19.76 C ATOM 36 C ARG A 14 27.340 -4.919 32.233 1.00 20.03 C ATOM 37 O ARG A 14 27.263 -3.657 32.231 1.00 19.99 O ATOM 38 CB ARG A 14 25.185 -6.129 32.251 1.00 19.02 C ATOM 39 CG ARG A 14 24.292 -7.230 32.854 1.00 22.22 C ATOM 40 CD ARG A 14 22.953 -7.264 32.209 1.00 21.56 C ATOM 41 NE ARG A 14 22.018 -8.135 32.971 1.00 24.49 N ATOM 42 CZ ARG A 14 20.729 -8.136 32.744 1.00 20.03 C ATOM 43 NH1 ARG A 14 20.266 -7.362 31.771 1.00 18.94 N ATOM 44 NH2 ARG A 14 19.865 -8.910 33.452 1.00 26.79 N ATOM 45 N THR A 15 28.204 -5.600 31.478 1.00 21.15 N ATOM 46 CA THR A 15 28.958 -4.923 30.414 1.00 23.81 C ATOM 47 C THR A 15 28.735 -5.738 29.137 1.00 25.10 C ATOM 48 O THR A 15 28.303 -6.886 29.189 1.00 24.94 O ATOM 49 CB THR A 15 30.448 -4.819 30.667 1.00 24.00 C ATOM 50 OG1 THR A 15 30.997 -6.149 30.732 1.00 27.04 O ATOM 51 CG2 THR A 15 30.750 -4.066 31.953 1.00 25.91 C ATOM 52 N LEU A 16 29.037 -5.117 27.999 1.00 26.08 N ATOM 53 CA LEU A 16 28.769 -5.699 26.704 1.00 28.26 C ATOM 54 C LEU A 16 29.625 -6.976 26.542 1.00 30.99 C ATOM 55 O LEU A 16 29.164 -7.991 25.993 1.00 31.09 O ATOM 56 CB LEU A 16 29.004 -4.631 25.618 1.00 29.43 C ATOM 57 CG LEU A 16 28.741 -5.004 24.157 1.00 28.83 C ATOM 58 CD1 LEU A 16 27.314 -5.490 23.947 1.00 30.36 C ATOM 59 CD2 LEU A 16 29.066 -3.767 23.318 1.00 31.43 C ATOM 60 N ALA A 17 30.814 -6.951 27.128 1.00 31.72 N ATOM 61 CA ALA A 17 31.721 -8.103 27.092 1.00 34.37 C ATOM 62 C ALA A 17 31.323 -9.230 28.052 1.00 35.09 C ATOM 63 O ALA A 17 31.439 -10.417 27.703 1.00 36.24 O ATOM 64 CB ALA A 17 33.176 -7.638 27.357 1.00 34.27 C ATOM 65 N SER A 18 30.837 -8.863 29.238 1.00 35.91 N ATOM 66 CA SER A 18 30.598 -9.812 30.340 1.00 36.48 C ATOM 67 C SER A 18 29.294 -10.607 30.197 1.00 37.09 C ATOM 68 O SER A 18 29.203 -11.742 30.723 1.00 38.05 O ATOM 69 CB SER A 18 30.634 -9.095 31.707 1.00 36.77 C ATOM 70 OG SER A 18 29.417 -8.408 32.014 1.00 39.79 O ATOM 71 N THR A 19 28.292 -10.037 29.502 1.00 34.84 N ATOM 72 CA THR A 19 27.011 -10.714 29.281 1.00 34.75 C ATOM 73 C THR A 19 26.502 -10.516 27.859 1.00 35.39 C ATOM 74 O THR A 19 25.402 -9.996 27.663 1.00 34.74 O ATOM 75 CB THR A 19 25.889 -10.332 30.319 1.00 34.25 C ATOM 76 OG1 THR A 19 25.567 -8.945 30.213 1.00 33.29 O ATOM 77 CG2 THR A 19 26.283 -10.611 31.784 1.00 35.39 C ATOM 78 N PRO A 20 27.277 -10.966 26.847 1.00 35.60 N ATOM 79 CA PRO A 20 26.937 -10.714 25.423 1.00 34.86 C ATOM 80 C PRO A 20 25.483 -11.053 25.026 1.00 33.32 C ATOM 81 O PRO A 20 24.822 -10.334 24.207 1.00 33.72 O ATOM 82 CB PRO A 20 27.976 -11.572 24.660 1.00 35.46 C ATOM 83 CG PRO A 20 28.623 -12.472 25.707 1.00 35.59 C ATOM 84 CD PRO A 20 28.492 -11.813 27.004 1.00 36.56 C ATOM 85 N ALA A 21 24.946 -12.099 25.644 1.00 31.14 N ATOM 86 CA ALA A 21 23.663 -12.622 25.221 1.00 29.83 C ATOM 87 C ALA A 21 22.464 -11.805 25.719 1.00 28.73 C ATOM 88 O ALA A 21 21.344 -11.948 25.224 1.00 30.01 O ATOM 89 CB ALA A 21 23.524 -14.050 25.699 1.00 29.43 C ATOM 90 N LEU A 22 22.708 -10.937 26.696 1.00 26.57 N ATOM 91 CA LEU A 22 21.629 -10.131 27.242 1.00 26.06 C ATOM 92 C LEU A 22 21.539 -8.697 26.647 1.00 25.66 C ATOM 93 O LEU A 22 20.821 -7.851 27.189 1.00 20.67 O ATOM 94 CB LEU A 22 21.848 -10.043 28.761 1.00 26.65 C ATOM 95 CG LEU A 22 21.725 -11.385 29.537 1.00 25.21 C ATOM 96 CD1 LEU A 22 21.821 -10.972 30.990 1.00 27.18 C ATOM 97 CD2 LEU A 22 20.385 -12.099 29.215 1.00 28.27 C ATOM 98 N TRP A 23 22.262 -8.432 25.563 1.00 24.55 N ATOM 99 CA TRP A 23 22.173 -7.089 24.901 1.00 24.48 C ATOM 100 C TRP A 23 21.405 -7.126 23.603 1.00 25.23 C ATOM 101 O TRP A 23 21.455 -8.148 22.859 1.00 26.54 O ATOM 102 CB TRP A 23 23.580 -6.515 24.668 1.00 23.24 C ATOM 103 CG TRP A 23 24.339 -6.294 25.934 1.00 23.74 C ATOM 104 CD1 TRP A 23 24.973 -7.247 26.689 1.00 22.56 C ATOM 105 CD2 TRP A 23 24.509 -5.045 26.627 1.00 20.07 C ATOM 106 NE1 TRP A 23 25.553 -6.666 27.799 1.00 21.64 N ATOM 107 CE2 TRP A 23 25.284 -5.314 27.787 1.00 21.60 C ATOM 108 CE3 TRP A 23 24.101 -3.692 26.359 1.00 17.57 C ATOM 109 CZ2 TRP A 23 25.678 -4.307 28.688 1.00 22.45 C ATOM 110 CZ3 TRP A 23 24.558 -2.653 27.281 1.00 18.08 C ATOM 111 CH2 TRP A 23 25.279 -3.005 28.441 1.00 22.18 C ATOM 112 N ALA A 24 20.687 -6.035 23.303 1.00 23.14 N ATOM 113 CA ALA A 24 20.108 -5.837 21.952 1.00 23.58 C ATOM 114 C ALA A 24 20.577 -4.467 21.493 1.00 25.52 C ATOM 115 O ALA A 24 20.931 -3.609 22.335 1.00 23.82 O ATOM 116 CB ALA A 24 18.632 -5.907 21.994 1.00 23.44 C ATOM 117 N SER A 25 20.544 -4.223 20.189 1.00 23.95 N ATOM 118 CA SER A 25 20.995 -2.954 19.684 1.00 24.83 C ATOM 119 C SER A 25 19.943 -2.192 18.865 1.00 23.09 C ATOM 120 O SER A 25 18.950 -2.742 18.326 1.00 24.81 O ATOM 121 CB SER A 25 22.262 -3.168 18.899 1.00 26.38 C ATOM 122 OG SER A 25 21.979 -3.961 17.769 1.00 32.16 O ATOM 123 N ILE A 26 20.218 -0.895 18.760 1.00 21.94 N ATOM 124 CA ILE A 26 19.428 0.063 18.016 1.00 21.28 C ATOM 125 C ILE A 26 20.469 0.756 17.108 1.00 22.65 C ATOM 126 O ILE A 26 21.538 1.207 17.561 1.00 20.09 O ATOM 127 CB ILE A 26 18.783 1.127 18.923 1.00 21.29 C ATOM 128 CG1 ILE A 26 17.755 0.419 19.835 1.00 22.43 C ATOM 129 CG2 ILE A 26 18.095 2.183 18.073 1.00 20.32 C ATOM 130 CD1 ILE A 26 17.199 1.238 21.006 1.00 19.85 C ATOM 131 N PRO A 27 20.210 0.730 15.770 1.00 23.71 N ATOM 132 CA PRO A 27 21.161 1.409 14.907 1.00 23.81 C ATOM 133 C PRO A 27 21.160 2.884 15.242 1.00 21.90 C ATOM 134 O PRO A 27 20.125 3.481 15.382 1.00 23.18 O ATOM 135 CB PRO A 27 20.640 1.091 13.464 1.00 23.75 C ATOM 136 CG PRO A 27 19.865 -0.228 13.636 1.00 23.80 C ATOM 137 CD PRO A 27 19.140 0.053 14.999 1.00 26.06 C ATOM 138 N CYS A 28 22.357 3.409 15.480 1.00 22.76 N ATOM 139 CA CYS A 28 22.511 4.771 16.003 1.00 22.75 C ATOM 140 C CYS A 28 23.957 5.184 15.880 1.00 23.15 C ATOM 141 O CYS A 28 24.832 4.732 16.631 1.00 24.92 O ATOM 142 CB CYS A 28 22.078 4.777 17.476 1.00 21.15 C ATOM 143 SG CYS A 28 22.034 6.477 18.149 1.00 24.64 S ATOM 144 N PRO A 29 24.254 6.043 14.889 1.00 22.72 N ATOM 145 CA PRO A 29 25.617 6.531 14.672 1.00 23.33 C ATOM 146 C PRO A 29 25.968 7.535 15.776 1.00 23.64 C ATOM 147 O PRO A 29 25.064 8.154 16.360 1.00 21.66 O ATOM 148 CB PRO A 29 25.537 7.322 13.357 1.00 22.14 C ATOM 149 CG PRO A 29 24.199 7.246 12.861 1.00 26.21 C ATOM 150 CD PRO A 29 23.309 6.450 13.831 1.00 23.01 C ATOM 151 N ARG A 30 27.269 7.725 15.998 1.00 25.74 N ATOM 152 CA ARG A 30 27.720 8.771 16.964 1.00 26.50 C ATOM 153 C ARG A 30 27.333 10.202 16.581 1.00 26.34 C ATOM 154 O ARG A 30 27.122 11.079 17.462 1.00 25.34 O ATOM 155 CB ARG A 30 29.200 8.558 17.329 1.00 28.57 C ATOM 156 CG ARG A 30 29.439 7.170 17.959 1.00 32.02 C ATOM 157 CD ARG A 30 30.293 7.166 19.220 1.00 42.59 C ATOM 158 NE ARG A 30 31.496 7.993 19.057 1.00 49.67 N ATOM 159 CZ ARG A 30 32.304 8.352 20.055 1.00 51.04 C ATOM 160 NH1 ARG A 30 32.053 7.945 21.308 1.00 51.78 N ATOM 161 NH2 ARG A 30 33.350 9.132 19.804 1.00 46.67 N ATOM 162 N SER A 31 27.185 10.489 15.280 1.00 24.10 N ATOM 163 CA SER A 31 26.525 11.709 14.867 1.00 23.44 C ATOM 164 C SER A 31 25.140 11.981 15.389 1.00 21.89 C ATOM 165 O SER A 31 24.692 13.154 15.491 1.00 24.43 O ATOM 166 CB SER A 31 26.545 11.830 13.316 1.00 24.11 C ATOM 167 OG SER A 31 25.562 10.965 12.729 1.00 30.13 O ATOM 168 N GLU A 32 24.405 10.909 15.773 1.00 17.47 N ATOM 169 CA GLU A 32 23.112 11.062 16.240 1.00 17.58 C ATOM 170 C GLU A 32 23.070 11.073 17.795 1.00 14.25 C ATOM 171 O GLU A 32 22.219 11.689 18.356 1.00 15.29 O ATOM 172 CB GLU A 32 22.207 9.910 15.751 1.00 16.05 C ATOM 173 CG GLU A 32 21.701 10.136 14.271 1.00 19.08 C ATOM 174 CD GLU A 32 21.032 11.424 14.087 1.00 16.32 C ATOM 175 OE1 GLU A 32 20.050 11.715 14.742 1.00 19.33 O ATOM 176 OE2 GLU A 32 21.477 12.157 13.142 1.00 22.00 O ATOM 177 N LEU A 33 24.090 10.470 18.411 1.00 13.93 N ATOM 178 CA LEU A 33 24.047 10.393 19.925 1.00 13.77 C ATOM 179 C LEU A 33 25.426 10.089 20.475 1.00 11.90 C ATOM 180 O LEU A 33 26.084 9.158 20.072 1.00 15.20 O ATOM 181 CB LEU A 33 23.110 9.191 20.396 1.00 11.05 C ATOM 182 CG LEU A 33 23.073 8.933 21.936 1.00 15.69 C ATOM 183 CD1 LEU A 33 22.571 10.154 22.733 1.00 12.76 C ATOM 184 CD2 LEU A 33 22.100 7.783 22.076 1.00 14.51 C ATOM 185 N ARG A 34 25.887 10.904 21.436 1.00 12.41 N ATOM 186 CA ARG A 34 27.048 10.565 22.277 1.00 13.23 C ATOM 187 C ARG A 34 26.550 10.478 23.723 1.00 13.03 C ATOM 188 O ARG A 34 26.254 11.529 24.351 1.00 13.09 O ATOM 189 CB ARG A 34 28.161 11.641 22.079 1.00 13.30 C ATOM 190 CG ARG A 34 28.994 11.397 20.876 1.00 16.57 C ATOM 191 CD ARG A 34 30.154 10.460 21.175 1.00 26.24 C ATOM 192 NE ARG A 34 31.056 11.088 22.153 1.00 27.83 N ATOM 193 CZ ARG A 34 32.001 11.992 21.923 1.00 31.90 C ATOM 194 NH1 ARG A 34 32.327 12.351 20.668 1.00 30.03 N ATOM 195 NH2 ARG A 34 32.665 12.513 22.967 1.00 28.39 N ATOM 196 N LEU A 35 26.434 9.239 24.236 1.00 12.74 N ATOM 197 CA LEU A 35 25.960 9.110 25.635 1.00 11.16 C ATOM 198 C LEU A 35 26.805 9.952 26.583 1.00 12.65 C ATOM 199 O LEU A 35 26.237 10.551 27.514 1.00 13.02 O ATOM 200 CB LEU A 35 26.054 7.658 26.059 1.00 11.75 C ATOM 201 CG LEU A 35 25.170 6.620 25.278 1.00 11.64 C ATOM 202 CD1 LEU A 35 25.498 5.171 25.650 1.00 13.85 C ATOM 203 CD2 LEU A 35 23.664 6.911 25.525 1.00 13.00 C ATOM 204 N ASP A 36 28.127 9.960 26.373 1.00 12.68 N ATOM 205 CA ASP A 36 28.983 10.702 27.335 1.00 13.35 C ATOM 206 C ASP A 36 28.757 12.204 27.303 1.00 12.39 C ATOM 207 O ASP A 36 29.174 12.950 28.232 1.00 15.43 O ATOM 208 CB ASP A 36 30.450 10.357 27.082 1.00 15.46 C ATOM 209 CG ASP A 36 30.941 10.709 25.693 1.00 20.17 C ATOM 210 OD1 ASP A 36 30.278 10.465 24.685 1.00 22.10 O ATOM 211 OD2 ASP A 36 32.112 11.101 25.607 1.00 27.78 O ATOM 212 N LEU A 37 28.171 12.732 26.213 1.00 12.24 N ATOM 213 CA LEU A 37 27.896 14.175 26.191 1.00 13.70 C ATOM 214 C LEU A 37 26.455 14.531 26.501 1.00 14.92 C ATOM 215 O LEU A 37 26.138 15.739 26.633 1.00 20.63 O ATOM 216 CB LEU A 37 28.243 14.804 24.771 1.00 14.89 C ATOM 217 CG LEU A 37 29.671 14.516 24.293 1.00 16.27 C ATOM 218 CD1 LEU A 37 29.855 15.232 22.908 1.00 18.54 C ATOM 219 CD2 LEU A 37 30.744 15.058 25.275 1.00 20.36 C ATOM 220 N VAL A 38 25.568 13.523 26.581 1.00 12.48 N ATOM 221 CA VAL A 38 24.183 13.758 26.810 1.00 13.24 C ATOM 222 C VAL A 38 23.815 13.425 28.276 1.00 13.07 C ATOM 223 O VAL A 38 23.277 14.257 29.003 1.00 15.37 O ATOM 224 CB VAL A 38 23.328 12.920 25.878 1.00 14.08 C ATOM 225 CG1 VAL A 38 21.858 12.997 26.268 1.00 17.63 C ATOM 226 CG2 VAL A 38 23.477 13.503 24.473 1.00 13.85 C ATOM 227 N LEU A 39 24.203 12.250 28.724 1.00 12.57 N ATOM 228 CA LEU A 39 23.690 11.766 30.034 1.00 11.97 C ATOM 229 C LEU A 39 24.196 12.456 31.298 1.00 13.49 C ATOM 230 O LEU A 39 23.451 12.452 32.270 1.00 12.54 O ATOM 231 CB LEU A 39 23.837 10.285 30.147 1.00 12.07 C ATOM 232 CG LEU A 39 23.061 9.472 29.066 1.00 12.98 C ATOM 233 CD1 LEU A 39 23.389 7.984 29.342 1.00 12.23 C ATOM 234 CD2 LEU A 39 21.510 9.714 29.099 1.00 14.08 C ATOM 235 N PRO A 40 25.429 13.011 31.295 1.00 13.26 N ATOM 236 CA PRO A 40 25.901 13.632 32.570 1.00 12.59 C ATOM 237 C PRO A 40 25.864 15.176 32.444 1.00 11.55 C ATOM 238 O PRO A 40 26.402 15.930 33.283 1.00 13.37 O ATOM 239 CB PRO A 40 27.330 13.175 32.626 1.00 14.64 C ATOM 240 CG PRO A 40 27.764 13.155 31.150 1.00 12.57 C ATOM 241 CD PRO A 40 26.549 12.808 30.345 1.00 13.07 C ATOM 242 N SER A 41 25.146 15.715 31.458 1.00 10.77 N ATOM 243 CA SER A 41 25.265 17.144 31.145 1.00 12.59 C ATOM 244 C SER A 41 24.098 18.018 31.649 1.00 11.92 C ATOM 245 O SER A 41 23.865 19.164 31.161 1.00 11.73 O ATOM 246 CB SER A 41 25.264 17.295 29.592 1.00 13.93 C ATOM 247 OG SER A 41 26.501 16.775 29.164 1.00 18.88 O ATOM 248 N GLY A 42 23.307 17.498 32.612 1.00 11.74 N ATOM 249 CA GLY A 42 22.208 18.275 33.197 1.00 12.42 C ATOM 250 C GLY A 42 20.898 18.275 32.453 1.00 10.66 C ATOM 251 O GLY A 42 20.144 19.196 32.649 1.00 12.26 O ATOM 252 N GLN A 43 20.682 17.228 31.646 1.00 10.62 N ATOM 253 CA GLN A 43 19.300 17.000 31.056 1.00 12.32 C ATOM 254 C GLN A 43 18.607 16.079 32.056 1.00 12.40 C ATOM 255 O GLN A 43 17.611 16.467 32.664 1.00 12.48 O ATOM 256 CB GLN A 43 19.317 16.345 29.696 1.00 10.93 C ATOM 257 CG GLN A 43 19.915 17.321 28.595 1.00 11.20 C ATOM 258 CD GLN A 43 19.708 16.685 27.286 1.00 13.39 C ATOM 259 OE1 GLN A 43 18.656 16.099 26.971 1.00 13.19 O ATOM 260 NE2 GLN A 43 20.722 16.838 26.439 1.00 13.95 N ATOM 261 N SER A 44 19.121 14.850 32.201 1.00 12.91 N ATOM 262 CA SER A 44 18.596 13.874 33.239 1.00 12.17 C ATOM 263 C SER A 44 19.721 13.805 34.269 1.00 13.48 C ATOM 264 O SER A 44 20.880 13.749 33.895 1.00 12.80 O ATOM 265 CB SER A 44 18.435 12.505 32.596 1.00 13.76 C ATOM 266 OG SER A 44 18.212 11.515 33.619 1.00 14.08 O ATOM 267 N PHE A 45 19.367 13.583 35.548 1.00 12.51 N ATOM 268 CA PHE A 45 20.319 13.413 36.634 1.00 11.36 C ATOM 269 C PHE A 45 20.340 11.946 37.045 1.00 14.45 C ATOM 270 O PHE A 45 20.928 11.646 38.075 1.00 16.48 O ATOM 271 CB PHE A 45 19.861 14.339 37.823 1.00 12.91 C ATOM 272 CG PHE A 45 19.883 15.785 37.399 1.00 12.52 C ATOM 273 CD1 PHE A 45 18.713 16.464 36.941 1.00 13.27 C ATOM 274 CD2 PHE A 45 21.135 16.445 37.415 1.00 13.12 C ATOM 275 CE1 PHE A 45 18.832 17.824 36.480 1.00 14.13 C ATOM 276 CE2 PHE A 45 21.241 17.706 36.998 1.00 13.27 C ATOM 277 CZ PHE A 45 20.127 18.448 36.509 1.00 13.59 C ATOM 278 N ARG A 46 19.726 11.098 36.244 1.00 14.51 N ATOM 279 CA ARG A 46 19.402 9.651 36.670 1.00 14.23 C ATOM 280 C ARG A 46 20.432 8.632 36.176 1.00 13.55 C ATOM 281 O ARG A 46 20.207 7.402 36.260 1.00 17.38 O ATOM 282 CB ARG A 46 18.019 9.233 36.168 1.00 16.76 C ATOM 283 CG ARG A 46 16.874 10.069 36.735 1.00 16.98 C ATOM 284 CD ARG A 46 16.488 9.747 38.233 1.00 21.09 C ATOM 285 NE ARG A 46 15.383 8.814 38.177 1.00 24.99 N ATOM 286 CZ ARG A 46 15.234 7.740 38.983 1.00 17.57 C ATOM 287 NH1 ARG A 46 16.148 7.374 39.869 1.00 20.89 N ATOM 288 NH2 ARG A 46 14.176 7.022 38.782 1.00 19.55 N ATOM 289 N TRP A 47 21.519 9.081 35.563 1.00 10.91 N ATOM 290 CA TRP A 47 22.428 8.120 34.891 1.00 11.91 C ATOM 291 C TRP A 47 23.834 8.225 35.476 1.00 12.37 C ATOM 292 O TRP A 47 24.376 9.376 35.685 1.00 15.06 O ATOM 293 CB TRP A 47 22.495 8.471 33.359 1.00 12.46 C ATOM 294 CG TRP A 47 21.148 8.227 32.729 1.00 11.43 C ATOM 295 CD1 TRP A 47 20.175 9.138 32.569 1.00 12.61 C ATOM 296 CD2 TRP A 47 20.671 6.999 32.219 1.00 11.19 C ATOM 297 NE1 TRP A 47 19.074 8.555 31.974 1.00 13.96 N ATOM 298 CE2 TRP A 47 19.377 7.228 31.738 1.00 12.25 C ATOM 299 CE3 TRP A 47 21.227 5.743 32.073 1.00 11.45 C ATOM 300 CZ2 TRP A 47 18.599 6.187 31.185 1.00 14.38 C ATOM 301 CZ3 TRP A 47 20.468 4.694 31.533 1.00 13.57 C ATOM 302 CH2 TRP A 47 19.157 4.941 31.099 1.00 12.81 C ATOM 303 N ARG A 48 24.479 7.081 35.619 1.00 13.83 N ATOM 304 CA ARG A 48 25.916 7.051 36.046 1.00 15.05 C ATOM 305 C ARG A 48 26.698 6.087 35.287 1.00 13.69 C ATOM 306 O ARG A 48 26.228 4.999 34.904 1.00 13.79 O ATOM 307 CB ARG A 48 26.004 6.572 37.534 1.00 17.15 C ATOM 308 CG ARG A 48 25.091 7.277 38.467 1.00 22.22 C ATOM 309 CD ARG A 48 25.893 8.391 39.007 1.00 21.17 C ATOM 310 NE ARG A 48 25.438 8.981 40.327 1.00 24.26 N ATOM 311 CZ ARG A 48 26.195 9.893 40.994 1.00 30.76 C ATOM 312 NH1 ARG A 48 27.400 10.254 40.513 1.00 34.72 N ATOM 313 NH2 ARG A 48 25.761 10.525 42.104 1.00 34.75 N ATOM 314 N GLU A 49 27.966 6.453 35.040 1.00 13.33 N ATOM 315 CA GLU A 49 28.804 5.627 34.285 1.00 14.51 C ATOM 316 C GLU A 49 29.472 4.576 35.237 1.00 15.79 C ATOM 317 O GLU A 49 30.609 4.791 35.714 1.00 19.00 O ATOM 318 CB GLU A 49 29.840 6.561 33.635 1.00 15.19 C ATOM 319 CG GLU A 49 30.675 5.845 32.526 1.00 15.67 C ATOM 320 CD GLU A 49 31.783 6.716 31.928 1.00 16.50 C ATOM 321 OE1 GLU A 49 31.980 7.883 32.320 1.00 18.47 O ATOM 322 OE2 GLU A 49 32.503 6.173 31.023 1.00 20.53 O ATOM 323 N GLN A 50 28.742 3.520 35.513 1.00 16.20 N ATOM 324 CA GLN A 50 29.178 2.635 36.626 1.00 17.68 C ATOM 325 C GLN A 50 30.327 1.741 36.223 1.00 20.44 C ATOM 326 O GLN A 50 31.054 1.228 37.115 1.00 22.57 O ATOM 327 CB GLN A 50 28.012 1.775 37.108 1.00 17.39 C ATOM 328 CG GLN A 50 26.870 2.511 37.830 1.00 20.40 C ATOM 329 CD GLN A 50 27.235 2.990 39.238 1.00 24.62 C ATOM 330 OE1 GLN A 50 28.258 2.563 39.812 1.00 29.54 O ATOM 331 NE2 GLN A 50 26.429 3.870 39.798 1.00 24.08 N ATOM 332 N SER A 51 30.503 1.486 34.923 1.00 19.87 N ATOM 333 CA SER A 51 31.683 0.786 34.315 1.00 21.28 C ATOM 334 C SER A 51 32.101 1.752 33.168 1.00 21.65 C ATOM 335 O SER A 51 31.263 2.473 32.660 1.00 18.65 O ATOM 336 CB SER A 51 31.320 -0.563 33.686 1.00 21.92 C ATOM 337 OG SER A 51 30.848 -1.454 34.718 1.00 30.22 O ATOM 338 N PRO A 52 33.374 1.748 32.775 1.00 21.13 N ATOM 339 CA PRO A 52 33.788 2.708 31.715 1.00 21.47 C ATOM 340 C PRO A 52 32.952 2.492 30.454 1.00 20.11 C ATOM 341 O PRO A 52 32.727 1.334 30.026 1.00 21.74 O ATOM 342 CB PRO A 52 35.284 2.365 31.499 1.00 22.56 C ATOM 343 CG PRO A 52 35.730 1.751 32.888 1.00 22.93 C ATOM 344 CD PRO A 52 34.518 1.022 33.398 1.00 22.18 C ATOM 345 N ALA A 53 32.393 3.607 29.965 1.00 19.19 N ATOM 346 CA ALA A 53 31.557 3.681 28.740 1.00 19.96 C ATOM 347 C ALA A 53 30.177 3.070 28.886 1.00 18.40 C ATOM 348 O ALA A 53 29.456 2.928 27.881 1.00 18.74 O ATOM 349 CB ALA A 53 32.309 3.031 27.538 1.00 19.47 C ATOM 350 N HIS A 54 29.827 2.562 30.109 1.00 15.84 N ATOM 351 CA HIS A 54 28.520 1.930 30.313 1.00 15.59 C ATOM 352 C HIS A 54 27.704 2.755 31.314 1.00 14.46 C ATOM 353 O HIS A 54 28.132 3.007 32.477 1.00 15.26 O ATOM 354 CB HIS A 54 28.719 0.509 30.903 1.00 17.05 C ATOM 355 CG HIS A 54 29.219 -0.499 29.897 1.00 17.40 C ATOM 356 ND1 HIS A 54 30.501 -0.456 29.378 1.00 19.38 N ATOM 357 CD2 HIS A 54 28.611 -1.573 29.329 1.00 17.71 C ATOM 358 CE1 HIS A 54 30.660 -1.494 28.563 1.00 16.46 C ATOM 359 NE2 HIS A 54 29.523 -2.149 28.469 1.00 20.93 N ATOM 360 N TRP A 55 26.542 3.195 30.845 1.00 12.47 N ATOM 361 CA TRP A 55 25.683 4.087 31.624 1.00 11.93 C ATOM 362 C TRP A 55 24.421 3.433 32.153 1.00 12.44 C ATOM 363 O TRP A 55 23.666 2.842 31.411 1.00 12.63 O ATOM 364 CB TRP A 55 25.273 5.306 30.736 1.00 12.02 C ATOM 365 CG TRP A 55 26.449 6.106 30.318 1.00 13.55 C ATOM 366 CD1 TRP A 55 27.314 5.862 29.228 1.00 12.35 C ATOM 367 CD2 TRP A 55 26.960 7.304 30.959 1.00 12.67 C ATOM 368 NE1 TRP A 55 28.307 6.792 29.231 1.00 14.67 N ATOM 369 CE2 TRP A 55 28.127 7.686 30.243 1.00 13.21 C ATOM 370 CE3 TRP A 55 26.550 8.084 32.054 1.00 13.41 C ATOM 371 CZ2 TRP A 55 28.906 8.807 30.640 1.00 14.42 C ATOM 372 CZ3 TRP A 55 27.298 9.173 32.462 1.00 14.93 C ATOM 373 CH2 TRP A 55 28.462 9.562 31.730 1.00 16.15 C ATOM 374 N SER A 56 24.258 3.467 33.489 1.00 13.81 N ATOM 375 CA SER A 56 23.112 2.797 34.097 1.00 12.40 C ATOM 376 C SER A 56 22.184 3.776 34.790 1.00 12.22 C ATOM 377 O SER A 56 22.606 4.797 35.359 1.00 13.83 O ATOM 378 CB SER A 56 23.608 1.754 35.143 1.00 10.52 C ATOM 379 OG SER A 56 24.326 0.723 34.510 1.00 13.32 O ATOM 380 N GLY A 57 20.887 3.493 34.669 1.00 12.02 N ATOM 381 CA GLY A 57 19.854 4.351 35.238 1.00 12.11 C ATOM 382 C GLY A 57 18.471 3.820 34.921 1.00 13.94 C ATOM 383 O GLY A 57 18.351 2.758 34.271 1.00 16.60 O ATOM 384 N VAL A 58 17.468 4.538 35.404 1.00 15.93 N ATOM 385 CA VAL A 58 16.079 4.131 35.256 1.00 15.24 C ATOM 386 C VAL A 58 15.438 4.849 34.017 1.00 18.49 C ATOM 387 O VAL A 58 15.473 6.087 33.913 1.00 20.24 O ATOM 388 CB VAL A 58 15.263 4.461 36.577 1.00 15.59 C ATOM 389 CG1 VAL A 58 13.833 4.000 36.443 1.00 16.04 C ATOM 390 CG2 VAL A 58 15.864 3.643 37.764 1.00 15.42 C ATOM 391 N LEU A 59 14.845 4.041 33.150 1.00 18.40 N ATOM 392 CA LEU A 59 14.246 4.537 31.898 1.00 19.22 C ATOM 393 C LEU A 59 12.952 3.752 31.803 1.00 21.06 C ATOM 394 O LEU A 59 12.936 2.486 31.809 1.00 21.78 O ATOM 395 CB LEU A 59 15.177 4.217 30.716 1.00 18.18 C ATOM 396 CG LEU A 59 14.869 4.807 29.317 1.00 18.56 C ATOM 397 CD1 LEU A 59 16.160 4.722 28.486 1.00 17.61 C ATOM 398 CD2 LEU A 59 13.739 4.031 28.678 1.00 19.72 C ATOM 399 N ALA A 60 11.857 4.517 31.710 1.00 23.82 N ATOM 400 CA ALA A 60 10.505 3.938 31.674 1.00 24.00 C ATOM 401 C ALA A 60 10.270 2.917 32.804 1.00 25.27 C ATOM 402 O ALA A 60 9.830 1.809 32.554 1.00 25.07 O ATOM 403 CB ALA A 60 10.194 3.328 30.217 1.00 24.05 C ATOM 404 N ASP A 61 10.599 3.311 34.051 1.00 25.74 N ATOM 405 CA ASP A 61 10.408 2.411 35.273 1.00 24.70 C ATOM 406 C ASP A 61 11.171 1.060 35.363 1.00 23.15 C ATOM 407 O ASP A 61 10.819 0.150 36.132 1.00 22.66 O ATOM 408 CB ASP A 61 8.932 2.168 35.507 1.00 26.22 C ATOM 409 CG ASP A 61 8.139 3.483 35.641 1.00 33.86 C ATOM 410 OD1 ASP A 61 8.494 4.327 36.514 1.00 41.29 O ATOM 411 OD2 ASP A 61 7.144 3.664 34.879 1.00 42.19 O ATOM 412 N GLN A 62 12.202 0.903 34.569 1.00 19.36 N ATOM 413 CA GLN A 62 13.051 -0.257 34.712 1.00 18.58 C ATOM 414 C GLN A 62 14.468 0.259 34.703 1.00 16.87 C ATOM 415 O GLN A 62 14.767 1.360 34.158 1.00 18.44 O ATOM 416 CB GLN A 62 12.845 -1.170 33.512 1.00 19.03 C ATOM 417 CG GLN A 62 11.420 -1.803 33.541 1.00 21.55 C ATOM 418 CD GLN A 62 11.333 -2.928 32.551 1.00 30.30 C ATOM 419 OE1 GLN A 62 11.464 -2.699 31.344 1.00 28.23 O ATOM 420 NE2 GLN A 62 11.151 -4.179 33.051 1.00 29.37 N ATOM 421 N VAL A 63 15.375 -0.540 35.229 1.00 15.03 N ATOM 422 CA VAL A 63 16.799 -0.187 35.116 1.00 13.72 C ATOM 423 C VAL A 63 17.365 -0.696 33.821 1.00 14.04 C ATOM 424 O VAL A 63 17.103 -1.816 33.393 1.00 15.18 O ATOM 425 CB VAL A 63 17.607 -0.812 36.306 1.00 13.41 C ATOM 426 CG1 VAL A 63 19.049 -0.433 36.268 1.00 16.74 C ATOM 427 CG2 VAL A 63 16.906 -0.289 37.606 1.00 16.80 C ATOM 428 N TRP A 64 18.217 0.140 33.176 1.00 13.76 N ATOM 429 CA TRP A 64 18.921 -0.208 31.954 1.00 13.02 C ATOM 430 C TRP A 64 20.373 0.098 32.070 1.00 12.55 C ATOM 431 O TRP A 64 20.757 1.001 32.830 1.00 12.17 O ATOM 432 CB TRP A 64 18.381 0.660 30.800 1.00 13.44 C ATOM 433 CG TRP A 64 16.993 0.371 30.376 1.00 13.47 C ATOM 434 CD1 TRP A 64 15.875 0.752 30.996 1.00 14.34 C ATOM 435 CD2 TRP A 64 16.607 -0.362 29.188 1.00 13.21 C ATOM 436 NE1 TRP A 64 14.762 0.378 30.246 1.00 16.41 N ATOM 437 CE2 TRP A 64 15.198 -0.313 29.135 1.00 13.67 C ATOM 438 CE3 TRP A 64 17.327 -1.059 28.185 1.00 15.42 C ATOM 439 CZ2 TRP A 64 14.457 -0.939 28.106 1.00 15.29 C ATOM 440 CZ3 TRP A 64 16.613 -1.652 27.159 1.00 14.70 C ATOM 441 CH2 TRP A 64 15.188 -1.581 27.117 1.00 16.54 C ATOM 442 N THR A 65 21.233 -0.622 31.360 1.00 13.26 N ATOM 443 CA THR A 65 22.582 -0.180 31.071 1.00 14.09 C ATOM 444 C THR A 65 22.698 -0.001 29.536 1.00 13.45 C ATOM 445 O THR A 65 22.180 -0.764 28.790 1.00 14.38 O ATOM 446 CB THR A 65 23.671 -1.171 31.522 1.00 14.39 C ATOM 447 OG1 THR A 65 23.470 -1.396 32.950 1.00 15.36 O ATOM 448 CG2 THR A 65 24.982 -0.642 31.343 1.00 14.96 C ATOM 449 N LEU A 66 23.372 1.085 29.169 1.00 14.35 N ATOM 450 CA LEU A 66 23.524 1.515 27.755 1.00 12.08 C ATOM 451 C LEU A 66 24.990 1.689 27.479 1.00 12.49 C ATOM 452 O LEU A 66 25.764 2.273 28.238 1.00 13.73 O ATOM 453 CB LEU A 66 22.768 2.833 27.558 1.00 12.75 C ATOM 454 CG LEU A 66 21.316 2.937 27.966 1.00 11.78 C ATOM 455 CD1 LEU A 66 20.805 4.359 27.776 1.00 15.62 C ATOM 456 CD2 LEU A 66 20.409 1.971 27.163 1.00 14.39 C ATOM 457 N THR A 67 25.397 1.259 26.246 1.00 14.02 N ATOM 458 CA THR A 67 26.741 1.554 25.837 1.00 15.47 C ATOM 459 C THR A 67 26.757 1.620 24.286 1.00 15.72 C ATOM 460 O THR A 67 25.773 1.224 23.669 1.00 16.24 O ATOM 461 CB THR A 67 27.752 0.457 26.360 1.00 16.41 C ATOM 462 OG1 THR A 67 29.117 0.919 26.126 1.00 18.51 O ATOM 463 CG2 THR A 67 27.423 -0.922 25.740 1.00 20.20 C ATOM 464 N GLN A 68 27.784 2.220 23.711 1.00 17.68 N ATOM 465 CA GLN A 68 27.734 2.328 22.217 1.00 16.86 C ATOM 466 C GLN A 68 29.013 1.937 21.568 1.00 19.62 C ATOM 467 O GLN A 68 30.058 2.102 22.116 1.00 20.03 O ATOM 468 CB GLN A 68 27.289 3.728 21.799 1.00 18.33 C ATOM 469 CG GLN A 68 28.160 4.807 22.099 1.00 20.46 C ATOM 470 CD GLN A 68 27.373 6.223 21.952 1.00 21.37 C ATOM 471 OE1 GLN A 68 27.504 7.062 22.827 1.00 18.45 O ATOM 472 NE2 GLN A 68 26.599 6.429 20.858 1.00 19.75 N ATOM 473 N THR A 69 28.846 1.372 20.384 1.00 21.25 N ATOM 474 CA THR A 69 29.959 1.295 19.433 1.00 26.38 C ATOM 475 C THR A 69 29.769 2.405 18.369 1.00 28.42 C ATOM 476 O THR A 69 28.895 3.306 18.495 1.00 28.59 O ATOM 477 CB THR A 69 29.980 -0.050 18.768 1.00 26.28 C ATOM 478 OG1 THR A 69 28.720 -0.260 18.100 1.00 30.88 O ATOM 479 CG2 THR A 69 30.253 -1.148 19.799 1.00 29.25 C ATOM 480 N GLU A 70 30.604 2.411 17.308 1.00 29.94 N ATOM 481 CA GLU A 70 30.473 3.494 16.319 1.00 31.09 C ATOM 482 C GLU A 70 29.088 3.596 15.647 1.00 29.75 C ATOM 483 O GLU A 70 28.572 4.725 15.359 1.00 30.76 O ATOM 484 CB GLU A 70 31.593 3.384 15.260 1.00 33.31 C ATOM 485 CG GLU A 70 31.648 4.624 14.304 1.00 38.63 C ATOM 486 CD GLU A 70 31.982 5.944 14.996 1.00 44.86 C ATOM 487 OE1 GLU A 70 31.392 6.975 14.587 1.00 47.89 O ATOM 488 OE2 GLU A 70 32.834 5.976 15.928 1.00 49.82 O ATOM 489 N GLU A 71 28.456 2.456 15.381 1.00 27.51 N ATOM 490 CA GLU A 71 27.200 2.572 14.679 1.00 27.67 C ATOM 491 C GLU A 71 25.974 2.114 15.451 1.00 24.15 C ATOM 492 O GLU A 71 24.856 2.157 14.909 1.00 24.08 O ATOM 493 CB GLU A 71 27.270 1.863 13.311 1.00 30.39 C ATOM 494 CG GLU A 71 28.298 2.507 12.329 1.00 35.61 C ATOM 495 CD GLU A 71 27.799 3.831 11.695 1.00 41.86 C ATOM 496 OE1 GLU A 71 26.611 3.914 11.271 1.00 47.11 O ATOM 497 OE2 GLU A 71 28.592 4.799 11.619 1.00 48.37 O ATOM 498 N GLN A 72 26.162 1.622 16.698 1.00 21.96 N ATOM 499 CA GLN A 72 25.063 0.954 17.397 1.00 20.86 C ATOM 500 C GLN A 72 24.931 1.496 18.853 1.00 16.39 C ATOM 501 O GLN A 72 25.934 1.685 19.490 1.00 19.00 O ATOM 502 CB GLN A 72 25.338 -0.569 17.511 1.00 21.54 C ATOM 503 CG GLN A 72 25.391 -1.348 16.161 1.00 26.78 C ATOM 504 CD GLN A 72 24.167 -1.237 15.337 1.00 32.82 C ATOM 505 OE1 GLN A 72 23.033 -1.112 15.839 1.00 33.24 O ATOM 506 NE2 GLN A 72 24.365 -1.277 14.000 1.00 35.66 N ATOM 507 N LEU A 73 23.700 1.627 19.302 1.00 17.05 N ATOM 508 CA LEU A 73 23.442 1.839 20.742 1.00 15.69 C ATOM 509 C LEU A 73 23.038 0.441 21.304 1.00 15.35 C ATOM 510 O LEU A 73 22.022 -0.142 20.852 1.00 17.63 O ATOM 511 CB LEU A 73 22.354 2.884 20.864 1.00 14.10 C ATOM 512 CG LEU A 73 21.754 3.017 22.313 1.00 15.65 C ATOM 513 CD1 LEU A 73 22.885 3.565 23.185 1.00 18.09 C ATOM 514 CD2 LEU A 73 20.622 3.900 22.327 1.00 15.78 C ATOM 515 N HIS A 74 23.819 -0.048 22.268 1.00 15.34 N ATOM 516 CA HIS A 74 23.648 -1.403 22.857 1.00 15.61 C ATOM 517 C HIS A 74 22.858 -1.219 24.172 1.00 16.14 C ATOM 518 O HIS A 74 23.258 -0.327 25.009 1.00 17.66 O ATOM 519 CB HIS A 74 25.009 -2.038 23.076 1.00 17.86 C ATOM 520 CG HIS A 74 25.746 -2.380 21.802 1.00 19.48 C ATOM 521 ND1 HIS A 74 25.436 -3.495 21.039 1.00 27.09 N ATOM 522 CD2 HIS A 74 26.779 -1.763 21.185 1.00 27.88 C ATOM 523 CE1 HIS A 74 26.239 -3.523 19.987 1.00 27.31 C ATOM 524 NE2 HIS A 74 27.069 -2.500 20.061 1.00 27.60 N ATOM 525 N CYS A 75 21.804 -2.016 24.352 1.00 15.15 N ATOM 526 CA CYS A 75 20.862 -1.825 25.519 1.00 15.68 C ATOM 527 C CYS A 75 20.680 -3.157 26.235 1.00 17.87 C ATOM 528 O CYS A 75 20.591 -4.246 25.616 1.00 17.88 O ATOM 529 CB CYS A 75 19.505 -1.370 25.060 1.00 15.70 C ATOM 530 SG CYS A 75 19.614 0.075 23.928 1.00 18.45 S ATOM 531 N THR A 76 20.603 -3.058 27.559 1.00 16.44 N ATOM 532 CA THR A 76 20.354 -4.289 28.404 1.00 16.19 C ATOM 533 C THR A 76 19.380 -3.792 29.488 1.00 16.07 C ATOM 534 O THR A 76 19.512 -2.666 29.976 1.00 15.44 O ATOM 535 CB THR A 76 21.622 -4.888 28.915 1.00 17.23 C ATOM 536 OG1 THR A 76 21.319 -6.249 29.396 1.00 19.39 O ATOM 537 CG2 THR A 76 22.335 -4.119 29.993 1.00 17.58 C ATOM 538 N VAL A 77 18.444 -4.640 29.869 1.00 16.27 N ATOM 539 CA VAL A 77 17.384 -4.278 30.830 1.00 15.95 C ATOM 540 C VAL A 77 17.324 -5.284 31.964 1.00 17.92 C ATOM 541 O VAL A 77 17.474 -6.477 31.746 1.00 18.77 O ATOM 542 CB VAL A 77 16.026 -4.031 30.161 1.00 16.35 C ATOM 543 CG1 VAL A 77 15.426 -5.370 29.557 1.00 16.36 C ATOM 544 CG2 VAL A 77 15.000 -3.330 31.087 1.00 16.54 C ATOM 545 N TYR A 78 17.169 -4.750 33.174 1.00 15.98 N ATOM 546 CA TYR A 78 17.081 -5.580 34.420 1.00 18.92 C ATOM 547 C TYR A 78 15.646 -5.427 34.924 1.00 20.15 C ATOM 548 O TYR A 78 15.175 -4.330 35.370 1.00 23.09 O ATOM 549 CB TYR A 78 18.038 -5.031 35.482 1.00 17.92 C ATOM 550 CG TYR A 78 19.468 -4.761 35.087 1.00 17.85 C ATOM 551 CD1 TYR A 78 19.819 -3.564 34.436 1.00 12.89 C ATOM 552 CD2 TYR A 78 20.497 -5.661 35.413 1.00 16.77 C ATOM 553 CE1 TYR A 78 21.080 -3.286 34.050 1.00 15.63 C ATOM 554 CE2 TYR A 78 21.819 -5.394 35.048 1.00 19.22 C ATOM 555 CZ TYR A 78 22.125 -4.154 34.394 1.00 17.39 C ATOM 556 OH TYR A 78 23.392 -3.880 34.073 1.00 17.45 O ATOM 557 N ARG A 79 14.952 -6.552 34.939 1.00 25.03 N ATOM 558 CA ARG A 79 13.530 -6.521 35.266 1.00 26.53 C ATOM 559 C ARG A 79 13.177 -6.776 36.759 1.00 28.76 C ATOM 560 O ARG A 79 12.148 -6.318 37.223 1.00 31.47 O ATOM 561 CB ARG A 79 12.758 -7.454 34.320 1.00 25.27 C ATOM 562 CG ARG A 79 12.896 -7.035 32.802 1.00 25.43 C ATOM 563 CD ARG A 79 11.872 -7.747 31.849 1.00 24.96 C ATOM 564 NE ARG A 79 12.317 -7.656 30.442 1.00 24.69 N ATOM 565 CZ ARG A 79 13.251 -8.415 29.858 1.00 21.29 C ATOM 566 NH1 ARG A 79 13.556 -8.196 28.580 1.00 22.91 N ATOM 567 NH2 ARG A 79 13.947 -9.374 30.517 1.00 24.97 N ATOM 568 N GLY A 80 14.037 -7.449 37.507 1.00 32.18 N ATOM 569 CA GLY A 80 13.616 -7.873 38.886 1.00 35.14 C ATOM 570 C GLY A 80 14.697 -8.436 39.782 1.00 36.78 C ATOM 571 O GLY A 80 15.539 -9.214 39.323 1.00 39.86 O ATOM 572 N ASP A 81 13.514 -9.928 39.343 0.00 42.07 N ATOM 573 CA ASP A 81 13.877 -11.302 39.671 0.00 44.35 C ATOM 574 C ASP A 81 12.829 -12.286 39.161 0.00 45.23 C ATOM 575 O ASP A 81 12.924 -13.489 39.403 0.00 45.96 O ATOM 576 CB ASP A 81 14.057 -11.462 41.182 0.00 44.93 C ATOM 577 CG ASP A 81 15.464 -11.132 41.639 0.00 46.44 C ATOM 578 OD1 ASP A 81 16.357 -11.007 40.776 0.00 47.69 O ATOM 579 OD2 ASP A 81 15.677 -10.998 42.863 0.00 48.02 O ATOM 580 N LYS A 82 11.831 -11.766 38.455 0.00 45.99 N ATOM 581 CA LYS A 82 10.583 -12.491 38.243 0.00 46.58 C ATOM 582 C LYS A 82 10.682 -13.415 37.034 0.00 46.55 C ATOM 583 O LYS A 82 10.343 -14.595 37.114 0.00 47.16 O ATOM 584 CB LYS A 82 9.419 -11.514 38.065 0.00 46.86 C ATOM 585 CG LYS A 82 8.907 -10.915 39.365 0.00 47.68 C ATOM 586 CD LYS A 82 7.390 -10.830 39.374 0.00 48.95 C ATOM 587 CE LYS A 82 6.792 -11.739 40.435 0.00 50.04 C ATOM 588 NZ LYS A 82 6.798 -13.167 40.011 0.00 50.51 N ATOM 589 N SER A 83 11.147 -12.869 35.915 0.00 46.01 N ATOM 590 CA SER A 83 11.891 -13.650 34.928 0.00 44.66 C ATOM 591 C SER A 83 13.394 -13.449 35.088 0.00 43.36 C ATOM 592 O SER A 83 13.877 -12.318 35.146 0.00 43.42 O ATOM 593 CB SER A 83 11.459 -13.279 33.508 0.00 45.02 C ATOM 594 OG SER A 83 11.175 -11.894 33.408 0.00 45.98 O ATOM 595 N GLN A 84 13.753 -14.145 35.049 1.00 37.24 N ATOM 596 CA GLN A 84 14.881 -14.732 34.311 1.00 37.30 C ATOM 597 C GLN A 84 15.473 -13.734 33.290 1.00 35.17 C ATOM 598 O GLN A 84 14.756 -13.234 32.407 1.00 35.99 O ATOM 599 CB GLN A 84 14.463 -15.976 33.529 1.00 38.86 C ATOM 600 CG GLN A 84 14.489 -17.293 34.313 1.00 46.38 C ATOM 601 CD GLN A 84 14.852 -18.496 33.429 1.00 53.23 C ATOM 602 OE1 GLN A 84 15.480 -18.351 32.361 1.00 57.24 O ATOM 603 NE2 GLN A 84 14.477 -19.691 33.884 1.00 55.12 N ATOM 604 N ALA A 85 16.776 -13.547 33.371 1.00 31.78 N ATOM 605 CA ALA A 85 17.480 -12.525 32.549 1.00 30.77 C ATOM 606 C ALA A 85 17.302 -12.798 31.058 1.00 30.64 C ATOM 607 O ALA A 85 17.404 -13.939 30.599 1.00 30.44 O ATOM 608 CB ALA A 85 18.957 -12.459 32.936 1.00 29.51 C ATOM 609 N SER A 86 16.986 -11.781 30.273 1.00 27.79 N ATOM 610 CA SER A 86 16.959 -11.979 28.838 1.00 28.29 C ATOM 611 C SER A 86 17.147 -10.625 28.152 1.00 27.42 C ATOM 612 O SER A 86 16.970 -9.596 28.794 1.00 24.75 O ATOM 613 CB SER A 86 15.618 -12.574 28.395 1.00 27.81 C ATOM 614 OG SER A 86 14.539 -11.722 28.739 1.00 29.83 O ATOM 615 N ARG A 87 17.424 -10.669 26.851 1.00 27.07 N ATOM 616 CA ARG A 87 17.569 -9.480 25.984 1.00 27.02 C ATOM 617 C ARG A 87 16.337 -8.603 26.076 1.00 24.82 C ATOM 618 O ARG A 87 15.244 -9.062 26.288 1.00 25.27 O ATOM 619 CB ARG A 87 17.717 -9.867 24.502 1.00 29.16 C ATOM 620 CG ARG A 87 19.134 -10.038 24.075 1.00 35.24 C ATOM 621 CD ARG A 87 19.199 -10.709 22.696 1.00 41.45 C ATOM 622 NE ARG A 87 20.574 -10.961 22.247 1.00 47.00 N ATOM 623 CZ ARG A 87 21.101 -12.181 22.108 1.00 50.24 C ATOM 624 NH1 ARG A 87 20.373 -13.259 22.410 1.00 52.34 N ATOM 625 NH2 ARG A 87 22.354 -12.336 21.670 1.00 51.31 N ATOM 626 N PRO A 88 16.517 -7.304 25.807 1.00 22.50 N ATOM 627 CA PRO A 88 15.321 -6.453 25.752 1.00 22.40 C ATOM 628 C PRO A 88 14.389 -6.899 24.600 1.00 23.93 C ATOM 629 O PRO A 88 14.885 -7.327 23.561 1.00 26.16 O ATOM 630 CB PRO A 88 15.931 -5.028 25.448 1.00 22.73 C ATOM 631 CG PRO A 88 17.270 -5.140 25.846 1.00 20.20 C ATOM 632 CD PRO A 88 17.761 -6.544 25.689 1.00 22.59 C ATOM 633 N THR A 89 13.096 -6.735 24.792 1.00 24.50 N ATOM 634 CA THR A 89 12.069 -7.016 23.749 1.00 27.23 C ATOM 635 C THR A 89 11.983 -5.841 22.776 1.00 27.96 C ATOM 636 O THR A 89 12.449 -4.743 23.108 1.00 26.50 O ATOM 637 CB THR A 89 10.696 -7.205 24.369 1.00 26.27 C ATOM 638 OG1 THR A 89 10.212 -5.962 24.892 1.00 27.32 O ATOM 639 CG2 THR A 89 10.715 -8.319 25.504 1.00 30.35 C ATOM 640 N PRO A 90 11.421 -6.061 21.547 1.00 27.96 N ATOM 641 CA PRO A 90 11.207 -4.928 20.671 1.00 27.43 C ATOM 642 C PRO A 90 10.463 -3.792 21.304 1.00 27.83 C ATOM 643 O PRO A 90 10.821 -2.606 21.057 1.00 27.45 O ATOM 644 CB PRO A 90 10.314 -5.548 19.567 1.00 28.33 C ATOM 645 CG PRO A 90 10.961 -6.933 19.450 1.00 28.99 C ATOM 646 CD PRO A 90 10.939 -7.315 20.904 1.00 28.56 C ATOM 647 N ASP A 91 9.424 -4.076 22.098 1.00 27.51 N ATOM 648 CA ASP A 91 8.689 -2.997 22.765 1.00 27.53 C ATOM 649 C ASP A 91 9.585 -2.261 23.748 1.00 25.71 C ATOM 650 O ASP A 91 9.472 -1.062 23.845 1.00 24.75 O ATOM 651 CB ASP A 91 7.451 -3.492 23.526 1.00 29.54 C ATOM 652 CG ASP A 91 6.321 -3.909 22.580 1.00 34.97 C ATOM 653 OD1 ASP A 91 5.254 -4.324 23.103 1.00 42.93 O ATOM 654 OD2 ASP A 91 6.490 -3.775 21.334 1.00 38.89 O ATOM 655 N GLU A 92 10.407 -2.984 24.503 1.00 23.70 N ATOM 656 CA GLU A 92 11.317 -2.314 25.437 1.00 22.12 C ATOM 657 C GLU A 92 12.309 -1.423 24.684 1.00 21.98 C ATOM 658 O GLU A 92 12.574 -0.300 25.135 1.00 22.28 O ATOM 659 CB GLU A 92 12.038 -3.320 26.340 1.00 22.04 C ATOM 660 CG GLU A 92 11.081 -3.979 27.319 1.00 23.65 C ATOM 661 CD GLU A 92 11.681 -5.210 28.020 1.00 21.21 C ATOM 662 OE1 GLU A 92 12.555 -5.901 27.443 1.00 21.59 O ATOM 663 OE2 GLU A 92 11.250 -5.498 29.168 1.00 25.38 O ATOM 664 N LEU A 93 12.858 -1.916 23.594 1.00 21.29 N ATOM 665 CA LEU A 93 13.762 -1.108 22.757 1.00 20.79 C ATOM 666 C LEU A 93 13.090 0.141 22.216 1.00 23.69 C ATOM 667 O LEU A 93 13.736 1.212 22.168 1.00 21.85 O ATOM 668 CB LEU A 93 14.335 -1.938 21.627 1.00 21.93 C ATOM 669 CG LEU A 93 15.671 -2.625 21.754 1.00 25.74 C ATOM 670 CD1 LEU A 93 16.569 -2.426 23.020 1.00 23.47 C ATOM 671 CD2 LEU A 93 15.768 -4.020 21.098 1.00 29.49 C ATOM 672 N GLU A 94 11.803 0.055 21.877 1.00 22.83 N ATOM 673 CA GLU A 94 11.034 1.251 21.476 1.00 25.99 C ATOM 674 C GLU A 94 10.953 2.342 22.538 1.00 24.66 C ATOM 675 O GLU A 94 10.926 3.556 22.230 1.00 23.67 O ATOM 676 CB GLU A 94 9.594 0.861 21.001 1.00 27.13 C ATOM 677 CG GLU A 94 9.528 0.580 19.542 1.00 35.12 C ATOM 678 CD GLU A 94 9.994 1.763 18.699 1.00 36.96 C ATOM 679 OE1 GLU A 94 9.497 2.892 18.885 1.00 39.18 O ATOM 680 OE2 GLU A 94 10.885 1.540 17.867 1.00 42.83 O ATOM 681 N ALA A 95 10.918 1.928 23.821 1.00 21.23 N ATOM 682 CA ALA A 95 10.934 2.845 24.928 1.00 21.10 C ATOM 683 C ALA A 95 12.254 3.647 24.970 1.00 19.02 C ATOM 684 O ALA A 95 12.245 4.853 25.300 1.00 18.13 O ATOM 685 CB ALA A 95 10.750 2.037 26.220 1.00 21.47 C ATOM 686 N VAL A 96 13.343 2.946 24.671 1.00 18.18 N ATOM 687 CA VAL A 96 14.688 3.590 24.620 1.00 15.66 C ATOM 688 C VAL A 96 14.712 4.609 23.427 1.00 15.24 C ATOM 689 O VAL A 96 15.143 5.754 23.573 1.00 16.19 O ATOM 690 CB VAL A 96 15.813 2.571 24.467 1.00 15.64 C ATOM 691 CG1 VAL A 96 17.180 3.336 24.289 1.00 16.06 C ATOM 692 CG2 VAL A 96 15.798 1.513 25.669 1.00 17.60 C ATOM 693 N ARG A 97 14.144 4.170 22.305 1.00 16.65 N ATOM 694 CA ARG A 97 14.111 5.068 21.118 1.00 17.95 C ATOM 695 C ARG A 97 13.304 6.310 21.418 1.00 17.47 C ATOM 696 O ARG A 97 13.675 7.433 20.983 1.00 17.30 O ATOM 697 CB ARG A 97 13.542 4.314 19.870 1.00 19.36 C ATOM 698 CG ARG A 97 14.476 3.303 19.320 1.00 22.33 C ATOM 699 CD ARG A 97 14.081 2.835 17.842 1.00 30.22 C ATOM 700 NE ARG A 97 14.472 3.861 16.839 1.00 32.22 N ATOM 701 CZ ARG A 97 13.611 4.729 16.319 1.00 34.27 C ATOM 702 NH1 ARG A 97 12.334 4.670 16.678 1.00 37.06 N ATOM 703 NH2 ARG A 97 14.010 5.642 15.447 1.00 30.81 N ATOM 704 N LYS A 98 12.199 6.206 22.127 1.00 16.74 N ATOM 705 CA LYS A 98 11.338 7.321 22.460 1.00 18.36 C ATOM 706 C LYS A 98 12.033 8.266 23.458 1.00 18.08 C ATOM 707 O LYS A 98 11.881 9.470 23.417 1.00 18.57 O ATOM 708 CB LYS A 98 9.983 6.857 23.030 1.00 20.38 C ATOM 709 CG LYS A 98 9.074 6.166 21.957 1.00 26.33 C ATOM 710 CD LYS A 98 7.564 6.249 22.370 1.00 35.14 C ATOM 711 CE LYS A 98 6.669 5.041 21.957 1.00 38.44 C ATOM 712 NZ LYS A 98 6.868 4.561 20.569 1.00 40.11 N ATOM 713 N TYR A 99 12.770 7.686 24.406 1.00 16.30 N ATOM 714 CA TYR A 99 13.434 8.500 25.399 1.00 16.00 C ATOM 715 C TYR A 99 14.565 9.353 24.770 1.00 13.16 C ATOM 716 O TYR A 99 14.767 10.481 25.219 1.00 15.06 O ATOM 717 CB TYR A 99 13.996 7.540 26.514 1.00 14.97 C ATOM 718 CG TYR A 99 14.681 8.201 27.624 1.00 14.54 C ATOM 719 CD1 TYR A 99 14.001 8.871 28.588 1.00 13.73 C ATOM 720 CD2 TYR A 99 16.059 8.100 27.720 1.00 12.10 C ATOM 721 CE1 TYR A 99 14.643 9.496 29.691 1.00 12.01 C ATOM 722 CE2 TYR A 99 16.781 8.761 28.873 1.00 11.54 C ATOM 723 CZ TYR A 99 16.035 9.420 29.812 1.00 11.51 C ATOM 724 OH TYR A 99 16.684 9.919 30.911 1.00 15.60 O ATOM 725 N PHE A 100 15.250 8.764 23.814 1.00 13.20 N ATOM 726 CA PHE A 100 16.293 9.492 23.073 1.00 12.71 C ATOM 727 C PHE A 100 15.708 10.267 21.870 1.00 16.34 C ATOM 728 O PHE A 100 16.484 10.896 21.166 1.00 17.76 O ATOM 729 CB PHE A 100 17.404 8.583 22.637 1.00 15.27 C ATOM 730 CG PHE A 100 18.278 8.169 23.784 1.00 12.49 C ATOM 731 CD1 PHE A 100 18.090 6.894 24.383 1.00 14.81 C ATOM 732 CD2 PHE A 100 19.257 9.042 24.301 1.00 12.77 C ATOM 733 CE1 PHE A 100 18.911 6.505 25.501 1.00 15.31 C ATOM 734 CE2 PHE A 100 20.031 8.685 25.420 1.00 13.11 C ATOM 735 CZ PHE A 100 19.881 7.456 26.026 1.00 12.17 C ATOM 736 N GLN A 101 14.400 10.145 21.676 1.00 16.41 N ATOM 737 CA GLN A 101 13.762 10.891 20.526 1.00 18.35 C ATOM 738 C GLN A 101 14.474 10.578 19.219 1.00 17.11 C ATOM 739 O GLN A 101 14.715 11.528 18.418 1.00 17.27 O ATOM 740 CB GLN A 101 13.774 12.433 20.764 1.00 19.65 C ATOM 741 CG GLN A 101 13.130 12.806 21.992 1.00 21.59 C ATOM 742 CD GLN A 101 12.726 14.229 22.023 1.00 23.05 C ATOM 743 OE1 GLN A 101 11.695 14.610 21.388 1.00 21.83 O ATOM 744 NE2 GLN A 101 13.442 15.039 22.808 1.00 15.74 N ATOM 745 N LEU A 102 14.762 9.327 18.894 1.00 16.43 N ATOM 746 CA LEU A 102 15.662 8.984 17.815 1.00 16.29 C ATOM 747 C LEU A 102 15.057 9.238 16.389 1.00 17.20 C ATOM 748 O LEU A 102 15.805 9.053 15.440 1.00 19.85 O ATOM 749 CB LEU A 102 16.162 7.559 17.988 1.00 17.41 C ATOM 750 CG LEU A 102 17.210 7.348 19.124 1.00 17.85 C ATOM 751 CD1 LEU A 102 17.685 5.921 19.078 1.00 23.18 C ATOM 752 CD2 LEU A 102 18.435 8.249 18.997 1.00 20.92 C ATOM 753 N ASP A 103 13.776 9.532 16.367 1.00 20.60 N ATOM 754 CA ASP A 103 13.103 9.923 15.051 1.00 23.22 C ATOM 755 C ASP A 103 13.575 11.286 14.666 1.00 24.34 C ATOM 756 O ASP A 103 13.480 11.646 13.491 1.00 26.17 O ATOM 757 CB ASP A 103 11.578 9.935 15.120 1.00 23.85 C ATOM 758 CG ASP A 103 10.964 8.537 15.026 1.00 27.52 C ATOM 759 OD1 ASP A 103 11.696 7.556 14.724 1.00 31.05 O ATOM 760 OD2 ASP A 103 9.722 8.486 15.235 1.00 37.48 O ATOM 761 N VAL A 104 14.072 12.078 15.623 1.00 21.82 N ATOM 762 CA VAL A 104 14.594 13.419 15.240 1.00 19.24 C ATOM 763 C VAL A 104 16.023 13.209 14.766 1.00 20.71 C ATOM 764 O VAL A 104 16.857 12.588 15.480 1.00 21.04 O ATOM 765 CB VAL A 104 14.547 14.421 16.370 1.00 16.77 C ATOM 766 CG1 VAL A 104 15.301 15.722 15.947 1.00 18.57 C ATOM 767 CG2 VAL A 104 13.162 14.719 16.819 1.00 18.78 C ATOM 768 N THR A 105 16.365 13.625 13.545 1.00 18.54 N ATOM 769 CA THR A 105 17.626 13.365 12.926 1.00 19.72 C ATOM 770 C THR A 105 18.512 14.554 13.310 1.00 19.96 C ATOM 771 O THR A 105 18.337 15.662 12.791 1.00 17.84 O ATOM 772 CB THR A 105 17.496 13.323 11.313 1.00 21.13 C ATOM 773 OG1 THR A 105 16.390 12.431 10.939 1.00 28.13 O ATOM 774 CG2 THR A 105 18.761 12.881 10.790 1.00 22.98 C ATOM 775 N LEU A 106 19.368 14.355 14.323 1.00 16.93 N ATOM 776 CA LEU A 106 20.308 15.341 14.785 1.00 16.35 C ATOM 777 C LEU A 106 21.224 15.853 13.698 1.00 16.82 C ATOM 778 O LEU A 106 21.483 17.083 13.678 1.00 18.45 O ATOM 779 CB LEU A 106 21.094 14.712 15.983 1.00 16.25 C ATOM 780 CG LEU A 106 21.811 15.735 16.849 1.00 18.54 C ATOM 781 CD1 LEU A 106 20.853 16.600 17.503 1.00 17.42 C ATOM 782 CD2 LEU A 106 22.803 15.089 17.789 1.00 15.53 C ATOM 783 N ALA A 107 21.704 14.987 12.781 1.00 17.82 N ATOM 784 CA ALA A 107 22.627 15.465 11.712 1.00 17.29 C ATOM 785 C ALA A 107 21.906 16.566 10.888 1.00 18.94 C ATOM 786 O ALA A 107 22.601 17.513 10.401 1.00 17.44 O ATOM 787 CB ALA A 107 23.141 14.353 10.823 1.00 18.88 C ATOM 788 N GLN A 108 20.601 16.399 10.665 1.00 15.64 N ATOM 789 CA GLN A 108 19.878 17.455 9.912 1.00 15.55 C ATOM 790 C GLN A 108 19.870 18.765 10.661 1.00 15.90 C ATOM 791 O GLN A 108 20.047 19.855 10.052 1.00 15.78 O ATOM 792 CB GLN A 108 18.447 17.000 9.466 1.00 12.48 C ATOM 793 CG GLN A 108 18.533 15.905 8.430 1.00 15.61 C ATOM 794 CD GLN A 108 18.640 16.412 6.973 1.00 15.86 C ATOM 795 OE1 GLN A 108 18.685 17.621 6.709 1.00 16.66 O ATOM 796 NE2 GLN A 108 18.743 15.456 6.047 1.00 19.71 N ATOM 797 N LEU A 109 19.578 18.737 11.966 1.00 13.51 N ATOM 798 CA LEU A 109 19.502 19.967 12.790 1.00 14.25 C ATOM 799 C LEU A 109 20.883 20.581 12.842 1.00 15.73 C ATOM 800 O LEU A 109 20.963 21.799 12.684 1.00 14.08 O ATOM 801 CB LEU A 109 19.094 19.561 14.241 1.00 13.88 C ATOM 802 CG LEU A 109 17.687 19.050 14.283 1.00 13.62 C ATOM 803 CD1 LEU A 109 17.408 18.652 15.796 1.00 16.44 C ATOM 804 CD2 LEU A 109 16.678 20.141 13.869 1.00 15.87 C ATOM 805 N TYR A 110 21.958 19.780 13.098 1.00 15.83 N ATOM 806 CA TYR A 110 23.353 20.362 13.147 1.00 15.44 C ATOM 807 C TYR A 110 23.666 21.082 11.836 1.00 17.23 C ATOM 808 O TYR A 110 24.252 22.173 11.828 1.00 16.91 O ATOM 809 CB TYR A 110 24.388 19.329 13.378 1.00 16.09 C ATOM 810 CG TYR A 110 24.751 18.996 14.850 1.00 15.88 C ATOM 811 CD1 TYR A 110 23.731 18.803 15.808 1.00 15.44 C ATOM 812 CD2 TYR A 110 26.081 18.941 15.212 1.00 14.35 C ATOM 813 CE1 TYR A 110 24.101 18.495 17.184 1.00 14.36 C ATOM 814 CE2 TYR A 110 26.451 18.598 16.580 1.00 12.87 C ATOM 815 CZ TYR A 110 25.435 18.431 17.489 1.00 12.86 C ATOM 816 OH TYR A 110 25.812 18.095 18.788 1.00 13.50 O ATOM 817 N HIS A 111 23.241 20.462 10.732 1.00 15.20 N ATOM 818 CA HIS A 111 23.488 21.123 9.434 1.00 16.10 C ATOM 819 C HIS A 111 22.781 22.453 9.337 1.00 17.34 C ATOM 820 O HIS A 111 23.432 23.481 8.882 1.00 16.59 O ATOM 821 CB HIS A 111 22.984 20.228 8.309 1.00 15.99 C ATOM 822 CG HIS A 111 23.115 20.884 6.994 1.00 18.22 C ATOM 823 ND1 HIS A 111 22.057 21.480 6.353 1.00 19.97 N ATOM 824 CD2 HIS A 111 24.197 21.017 6.200 1.00 21.21 C ATOM 825 CE1 HIS A 111 22.489 21.984 5.191 1.00 20.50 C ATOM 826 NE2 HIS A 111 23.776 21.717 5.082 1.00 26.08 N ATOM 827 N HIS A 112 21.509 22.544 9.717 1.00 15.19 N ATOM 828 CA HIS A 112 20.739 23.775 9.661 1.00 15.48 C ATOM 829 C HIS A 112 21.380 24.787 10.604 1.00 17.89 C ATOM 830 O HIS A 112 21.562 25.943 10.239 1.00 19.29 O ATOM 831 CB HIS A 112 19.223 23.576 9.988 1.00 18.06 C ATOM 832 CG HIS A 112 18.473 24.850 10.215 1.00 20.20 C ATOM 833 ND1 HIS A 112 18.250 25.766 9.198 1.00 25.53 N ATOM 834 CD2 HIS A 112 17.983 25.416 11.349 1.00 26.87 C ATOM 835 CE1 HIS A 112 17.597 26.799 9.692 1.00 28.47 C ATOM 836 NE2 HIS A 112 17.442 26.630 10.992 1.00 30.78 N ATOM 837 N TRP A 113 21.661 24.408 11.869 1.00 15.42 N ATOM 838 CA TRP A 113 22.127 25.435 12.780 1.00 14.32 C ATOM 839 C TRP A 113 23.506 25.943 12.307 1.00 16.60 C ATOM 840 O TRP A 113 23.743 27.148 12.434 1.00 17.62 O ATOM 841 CB TRP A 113 22.255 24.856 14.225 1.00 14.00 C ATOM 842 CG TRP A 113 20.933 24.411 14.774 1.00 12.98 C ATOM 843 CD1 TRP A 113 19.710 24.997 14.643 1.00 15.47 C ATOM 844 CD2 TRP A 113 20.761 23.291 15.659 1.00 15.48 C ATOM 845 NE1 TRP A 113 18.728 24.279 15.388 1.00 17.16 N ATOM 846 CE2 TRP A 113 19.392 23.225 15.976 1.00 15.99 C ATOM 847 CE3 TRP A 113 21.657 22.259 16.139 1.00 13.54 C ATOM 848 CZ2 TRP A 113 18.866 22.193 16.809 1.00 14.90 C ATOM 849 CZ3 TRP A 113 21.125 21.235 16.932 1.00 13.87 C ATOM 850 CH2 TRP A 113 19.761 21.250 17.280 1.00 15.75 C ATOM 851 N GLY A 114 24.355 25.065 11.804 1.00 16.28 N ATOM 852 CA GLY A 114 25.746 25.475 11.372 1.00 18.44 C ATOM 853 C GLY A 114 25.643 26.376 10.141 1.00 19.26 C ATOM 854 O GLY A 114 26.490 27.253 9.934 1.00 21.21 O ATOM 855 N SER A 115 24.590 26.194 9.359 1.00 18.44 N ATOM 856 CA SER A 115 24.382 27.071 8.161 1.00 18.91 C ATOM 857 C SER A 115 23.955 28.502 8.467 1.00 20.09 C ATOM 858 O SER A 115 24.243 29.427 7.679 1.00 22.67 O ATOM 859 CB SER A 115 23.281 26.454 7.283 1.00 20.14 C ATOM 860 OG SER A 115 23.770 25.234 6.831 1.00 31.78 O ATOM 861 N VAL A 116 23.249 28.711 9.541 1.00 18.31 N ATOM 862 CA VAL A 116 22.845 30.031 9.998 1.00 18.33 C ATOM 863 C VAL A 116 23.742 30.619 11.073 1.00 18.10 C ATOM 864 O VAL A 116 23.568 31.812 11.500 1.00 21.58 O ATOM 865 CB VAL A 116 21.366 30.101 10.453 1.00 20.33 C ATOM 866 CG1 VAL A 116 20.427 29.726 9.285 1.00 24.29 C ATOM 867 CG2 VAL A 116 21.102 29.246 11.733 1.00 20.17 C ATOM 868 N ASP A 117 24.706 29.839 11.535 1.00 16.74 N ATOM 869 CA ASP A 117 25.444 30.298 12.702 1.00 15.91 C ATOM 870 C ASP A 117 26.806 29.767 12.637 1.00 15.90 C ATOM 871 O ASP A 117 27.156 28.588 13.016 1.00 15.85 O ATOM 872 CB ASP A 117 24.715 29.885 14.048 1.00 14.91 C ATOM 873 CG ASP A 117 25.501 30.250 15.273 1.00 15.28 C ATOM 874 OD1 ASP A 117 25.055 29.887 16.403 1.00 14.43 O ATOM 875 OD2 ASP A 117 26.638 30.773 15.190 1.00 14.33 O ATOM 876 N SER A 118 27.729 30.625 12.163 1.00 14.26 N ATOM 877 CA SER A 118 29.079 30.207 12.026 1.00 16.34 C ATOM 878 C SER A 118 29.820 29.763 13.278 1.00 15.72 C ATOM 879 O SER A 118 30.664 28.877 13.244 1.00 17.36 O ATOM 880 CB SER A 118 29.811 31.465 11.410 1.00 17.48 C ATOM 881 OG SER A 118 31.114 31.136 11.148 1.00 27.15 O ATOM 882 N HIS A 119 29.409 30.300 14.442 1.00 16.46 N ATOM 883 CA HIS A 119 30.070 29.864 15.665 1.00 15.35 C ATOM 884 C HIS A 119 29.540 28.429 16.042 1.00 14.47 C ATOM 885 O HIS A 119 30.316 27.606 16.528 1.00 16.94 O ATOM 886 CB HIS A 119 29.653 30.819 16.801 1.00 15.31 C ATOM 887 CG HIS A 119 30.007 30.297 18.141 1.00 16.05 C ATOM 888 ND1 HIS A 119 31.313 30.212 18.572 1.00 17.34 N ATOM 889 CD2 HIS A 119 29.228 29.803 19.143 1.00 14.62 C ATOM 890 CE1 HIS A 119 31.334 29.610 19.753 1.00 16.26 C ATOM 891 NE2 HIS A 119 30.087 29.394 20.148 1.00 16.68 N ATOM 892 N PHE A 120 28.228 28.226 15.878 1.00 15.58 N ATOM 893 CA PHE A 120 27.690 26.889 16.132 1.00 15.72 C ATOM 894 C PHE A 120 28.405 25.886 15.294 1.00 17.29 C ATOM 895 O PHE A 120 28.771 24.779 15.737 1.00 18.02 O ATOM 896 CB PHE A 120 26.179 26.862 15.867 1.00 15.08 C ATOM 897 CG PHE A 120 25.591 25.541 16.271 1.00 18.37 C ATOM 898 CD1 PHE A 120 25.026 25.422 17.520 1.00 18.83 C ATOM 899 CD2 PHE A 120 25.781 24.441 15.458 1.00 16.91 C ATOM 900 CE1 PHE A 120 24.567 24.133 17.918 1.00 19.45 C ATOM 901 CE2 PHE A 120 25.311 23.095 15.855 1.00 18.52 C ATOM 902 CZ PHE A 120 24.769 23.003 17.103 1.00 17.59 C ATOM 903 N GLN A 121 28.617 26.237 14.042 1.00 17.73 N ATOM 904 CA GLN A 121 29.289 25.308 13.158 1.00 20.38 C ATOM 905 C GLN A 121 30.661 24.907 13.690 1.00 23.47 C ATOM 906 O GLN A 121 31.040 23.747 13.641 1.00 22.81 O ATOM 907 CB GLN A 121 29.401 25.920 11.789 1.00 22.58 C ATOM 908 CG GLN A 121 30.011 25.043 10.694 1.00 26.74 C ATOM 909 CD GLN A 121 29.908 25.801 9.369 1.00 38.13 C ATOM 910 OE1 GLN A 121 29.281 25.334 8.406 1.00 43.54 O ATOM 911 NE2 GLN A 121 30.453 27.020 9.346 1.00 42.62 N ATOM 912 N GLU A 122 31.417 25.873 14.231 1.00 21.96 N ATOM 913 CA GLU A 122 32.696 25.517 14.809 1.00 23.13 C ATOM 914 C GLU A 122 32.568 24.591 16.039 1.00 24.28 C ATOM 915 O GLU A 122 33.311 23.598 16.152 1.00 25.02 O ATOM 916 CB GLU A 122 33.522 26.788 15.100 1.00 26.22 C ATOM 917 CG GLU A 122 33.645 27.657 13.867 1.00 31.81 C ATOM 918 CD GLU A 122 34.814 28.655 13.874 1.00 45.70 C ATOM 919 OE1 GLU A 122 34.603 29.830 14.300 1.00 49.55 O ATOM 920 OE2 GLU A 122 35.935 28.265 13.435 1.00 48.38 O ATOM 921 N VAL A 123 31.669 24.895 16.958 1.00 22.97 N ATOM 922 CA VAL A 123 31.510 24.053 18.183 1.00 23.73 C ATOM 923 C VAL A 123 31.040 22.651 17.831 1.00 24.01 C ATOM 924 O VAL A 123 31.512 21.669 18.436 1.00 23.17 O ATOM 925 CB VAL A 123 30.513 24.701 19.160 1.00 22.78 C ATOM 926 CG1 VAL A 123 30.295 23.795 20.470 1.00 26.59 C ATOM 927 CG2 VAL A 123 31.067 26.052 19.528 1.00 23.34 C ATOM 928 N ALA A 124 30.094 22.572 16.912 1.00 24.00 N ATOM 929 CA ALA A 124 29.441 21.328 16.478 1.00 26.89 C ATOM 930 C ALA A 124 30.485 20.326 16.096 1.00 29.66 C ATOM 931 O ALA A 124 30.305 19.110 16.322 1.00 29.67 O ATOM 932 CB ALA A 124 28.520 21.566 15.281 1.00 26.16 C ATOM 933 N GLN A 125 31.595 20.810 15.545 1.00 30.95 N ATOM 934 CA GLN A 125 32.547 19.868 15.022 1.00 33.86 C ATOM 935 C GLN A 125 33.205 19.033 16.107 1.00 32.52 C ATOM 936 O GLN A 125 33.462 17.863 15.871 1.00 34.73 O ATOM 937 CB GLN A 125 33.540 20.516 14.040 1.00 35.03 C ATOM 938 CG GLN A 125 33.051 20.300 12.611 1.00 41.86 C ATOM 939 CD GLN A 125 33.852 21.076 11.594 1.00 50.33 C ATOM 940 OE1 GLN A 125 33.539 21.074 10.395 1.00 53.84 O ATOM 941 NE2 GLN A 125 34.888 21.766 12.067 1.00 54.67 N ATOM 942 N LYS A 126 33.388 19.595 17.294 1.00 31.47 N ATOM 943 CA LYS A 126 33.930 18.893 18.449 1.00 30.07 C ATOM 944 C LYS A 126 32.863 18.212 19.338 1.00 28.14 C ATOM 945 O LYS A 126 33.180 17.325 20.135 1.00 29.36 O ATOM 946 CB LYS A 126 34.772 19.847 19.305 1.00 31.50 C ATOM 947 CG LYS A 126 35.944 20.572 18.536 1.00 37.06 C ATOM 948 CD LYS A 126 36.870 21.362 19.500 1.00 42.29 C ATOM 949 CE LYS A 126 38.080 21.949 18.751 1.00 42.44 C ATOM 950 NZ LYS A 126 38.945 22.752 19.648 1.00 44.83 N ATOM 951 N PHE A 127 31.597 18.623 19.218 1.00 24.07 N ATOM 952 CA PHE A 127 30.559 18.134 20.142 1.00 20.71 C ATOM 953 C PHE A 127 29.430 17.504 19.354 1.00 19.89 C ATOM 954 O PHE A 127 28.341 18.031 19.350 1.00 18.92 O ATOM 955 CB PHE A 127 30.067 19.263 21.055 1.00 20.38 C ATOM 956 CG PHE A 127 31.102 19.653 22.050 1.00 23.31 C ATOM 957 CD1 PHE A 127 32.031 20.672 21.746 1.00 24.10 C ATOM 958 CD2 PHE A 127 31.227 18.975 23.249 1.00 26.45 C ATOM 959 CE1 PHE A 127 33.035 21.039 22.699 1.00 26.35 C ATOM 960 CE2 PHE A 127 32.220 19.321 24.174 1.00 30.97 C ATOM 961 CZ PHE A 127 33.137 20.372 23.875 1.00 29.10 C ATOM 962 N GLN A 128 29.705 16.370 18.721 1.00 19.36 N ATOM 963 CA GLN A 128 28.665 15.736 17.863 1.00 19.13 C ATOM 964 C GLN A 128 27.791 14.907 18.814 1.00 17.93 C ATOM 965 O GLN A 128 28.201 14.564 19.965 1.00 18.49 O ATOM 966 CB GLN A 128 29.310 14.773 16.863 1.00 20.86 C ATOM 967 CG GLN A 128 30.020 13.647 17.656 1.00 28.82 C ATOM 968 CD GLN A 128 30.461 12.344 16.966 1.00 37.12 C ATOM 969 OE1 GLN A 128 30.965 11.437 17.668 1.00 36.67 O ATOM 970 NE2 GLN A 128 30.315 12.237 15.627 1.00 38.89 N ATOM 971 N GLY A 129 26.558 14.717 18.391 1.00 14.50 N ATOM 972 CA GLY A 129 25.709 13.716 19.106 1.00 13.82 C ATOM 973 C GLY A 129 25.052 14.262 20.352 1.00 12.45 C ATOM 974 O GLY A 129 24.591 13.426 21.168 1.00 12.48 O ATOM 975 N VAL A 130 25.003 15.551 20.531 1.00 11.85 N ATOM 976 CA VAL A 130 24.274 16.145 21.681 1.00 11.68 C ATOM 977 C VAL A 130 22.853 16.314 21.265 1.00 14.18 C ATOM 978 O VAL A 130 22.468 17.334 20.645 1.00 15.84 O ATOM 979 CB VAL A 130 24.845 17.477 22.217 1.00 11.69 C ATOM 980 CG1 VAL A 130 24.126 17.906 23.476 1.00 15.59 C ATOM 981 CG2 VAL A 130 26.240 17.285 22.526 1.00 13.01 C ATOM 982 N ARG A 131 22.025 15.347 21.623 1.00 13.85 N ATOM 983 CA ARG A 131 20.606 15.469 21.359 1.00 13.39 C ATOM 984 C ARG A 131 19.806 15.627 22.670 1.00 13.85 C ATOM 985 O ARG A 131 20.410 15.531 23.739 1.00 13.44 O ATOM 986 CB ARG A 131 20.154 14.245 20.568 1.00 13.99 C ATOM 987 CG ARG A 131 20.205 12.971 21.464 1.00 13.01 C ATOM 988 CD ARG A 131 19.399 11.835 20.885 1.00 18.41 C ATOM 989 NE ARG A 131 19.636 11.702 19.515 1.00 28.05 N ATOM 990 CZ ARG A 131 18.844 11.983 18.468 1.00 17.70 C ATOM 991 NH1 ARG A 131 17.532 12.206 18.503 1.00 21.32 N ATOM 992 NH2 ARG A 131 19.459 11.812 17.357 1.00 19.75 N ATOM 993 N LEU A 132 18.513 15.760 22.587 1.00 13.30 N ATOM 994 CA LEU A 132 17.749 16.059 23.784 1.00 13.99 C ATOM 995 C LEU A 132 16.888 14.858 24.161 1.00 15.54 C ATOM 996 O LEU A 132 16.158 14.296 23.274 1.00 15.60 O ATOM 997 CB LEU A 132 16.852 17.264 23.418 1.00 16.64 C ATOM 998 CG LEU A 132 16.258 18.092 24.500 1.00 19.14 C ATOM 999 CD1 LEU A 132 17.338 18.964 25.150 1.00 17.97 C ATOM 1000 CD2 LEU A 132 15.050 18.935 23.895 1.00 19.16 C ATOM 1001 N LEU A 133 16.893 14.527 25.456 1.00 14.45 N ATOM 1002 CA LEU A 133 16.031 13.423 25.903 1.00 13.85 C ATOM 1003 C LEU A 133 14.597 13.938 25.962 1.00 15.07 C ATOM 1004 O LEU A 133 14.335 15.117 26.114 1.00 15.18 O ATOM 1005 CB LEU A 133 16.508 13.043 27.293 1.00 14.97 C ATOM 1006 CG LEU A 133 17.978 12.663 27.358 1.00 14.18 C ATOM 1007 CD1 LEU A 133 18.345 12.401 28.811 1.00 15.93 C ATOM 1008 CD2 LEU A 133 18.357 11.482 26.551 1.00 12.57 C ATOM 1009 N ARG A 134 13.661 12.972 25.910 1.00 15.45 N ATOM 1010 CA ARG A 134 12.243 13.264 26.143 1.00 15.79 C ATOM 1011 C ARG A 134 11.895 12.613 27.465 1.00 17.02 C ATOM 1012 O ARG A 134 11.847 11.359 27.536 1.00 18.51 O ATOM 1013 CB ARG A 134 11.395 12.667 25.046 1.00 18.96 C ATOM 1014 CG ARG A 134 9.915 13.089 25.268 1.00 20.98 C ATOM 1015 CD ARG A 134 9.119 12.757 23.934 1.00 28.69 C ATOM 1016 NE ARG A 134 7.743 13.290 23.984 1.00 31.18 N ATOM 1017 CZ ARG A 134 6.642 12.567 24.287 1.00 33.93 C ATOM 1018 NH1 ARG A 134 6.734 11.261 24.600 1.00 31.92 N ATOM 1019 NH2 ARG A 134 5.445 13.164 24.286 1.00 33.21 N ATOM 1020 N GLN A 135 11.797 13.472 28.452 1.00 14.72 N ATOM 1021 CA GLN A 135 11.674 13.080 29.873 1.00 15.16 C ATOM 1022 C GLN A 135 10.207 13.001 30.328 1.00 17.18 C ATOM 1023 O GLN A 135 9.329 13.711 29.837 1.00 18.50 O ATOM 1024 CB GLN A 135 12.466 13.946 30.803 1.00 16.43 C ATOM 1025 CG GLN A 135 14.003 14.011 30.349 1.00 14.27 C ATOM 1026 CD GLN A 135 14.767 14.909 31.308 1.00 23.08 C ATOM 1027 OE1 GLN A 135 14.598 14.763 32.498 1.00 24.57 O ATOM 1028 NE2 GLN A 135 15.578 15.882 30.814 1.00 15.47 N ATOM 1029 N ASP A 136 9.954 12.123 31.289 1.00 18.36 N ATOM 1030 CA ASP A 136 8.672 12.160 31.958 1.00 19.24 C ATOM 1031 C ASP A 136 8.402 13.489 32.638 1.00 17.14 C ATOM 1032 O ASP A 136 9.250 14.077 33.323 1.00 17.36 O ATOM 1033 CB ASP A 136 8.702 11.015 33.038 1.00 18.43 C ATOM 1034 CG ASP A 136 7.471 11.069 33.969 1.00 25.32 C ATOM 1035 OD1 ASP A 136 6.385 10.621 33.491 1.00 29.05 O ATOM 1036 OD2 ASP A 136 7.626 11.580 35.103 1.00 27.39 O ATOM 1037 N PRO A 137 7.180 14.069 32.466 1.00 17.42 N ATOM 1038 CA PRO A 137 6.952 15.334 33.089 1.00 16.98 C ATOM 1039 C PRO A 137 7.169 15.515 34.586 1.00 16.83 C ATOM 1040 O PRO A 137 7.699 16.519 35.062 1.00 17.06 O ATOM 1041 CB PRO A 137 5.463 15.652 32.673 1.00 19.11 C ATOM 1042 CG PRO A 137 5.345 15.067 31.422 1.00 21.31 C ATOM 1043 CD PRO A 137 6.077 13.707 31.541 1.00 19.43 C ATOM 1044 N ILE A 138 6.690 14.558 35.491 1.00 15.53 N ATOM 1045 CA ILE A 138 6.928 14.704 36.905 1.00 17.10 C ATOM 1046 C ILE A 138 8.409 14.637 37.289 1.00 14.50 C ATOM 1047 O ILE A 138 8.887 15.435 38.034 1.00 15.92 O ATOM 1048 CB ILE A 138 6.133 13.575 37.775 1.00 16.40 C ATOM 1049 CG1 ILE A 138 4.614 13.784 37.638 1.00 22.38 C ATOM 1050 CG2 ILE A 138 6.596 13.512 39.205 1.00 20.45 C ATOM 1051 CD1 ILE A 138 4.112 15.142 38.138 1.00 21.62 C ATOM 1052 N GLU A 139 9.114 13.650 36.707 1.00 16.86 N ATOM 1053 CA GLU A 139 10.553 13.518 37.008 1.00 16.19 C ATOM 1054 C GLU A 139 11.351 14.828 36.574 1.00 15.10 C ATOM 1055 O GLU A 139 12.127 15.385 37.380 1.00 15.31 O ATOM 1056 CB GLU A 139 11.146 12.315 36.329 1.00 15.62 C ATOM 1057 CG GLU A 139 12.630 12.244 36.447 1.00 20.96 C ATOM 1058 CD GLU A 139 13.183 10.842 36.447 1.00 27.39 C ATOM 1059 OE1 GLU A 139 14.311 10.687 36.924 1.00 36.44 O ATOM 1060 OE2 GLU A 139 12.542 9.912 36.006 1.00 29.55 O ATOM 1061 N CYS A 140 11.023 15.322 35.372 1.00 16.53 N ATOM 1062 CA CYS A 140 11.628 16.575 34.858 1.00 16.24 C ATOM 1063 C CYS A 140 11.287 17.771 35.729 1.00 15.44 C ATOM 1064 O CYS A 140 12.162 18.527 36.188 1.00 16.93 O ATOM 1065 CB CYS A 140 11.084 16.734 33.475 1.00 14.32 C ATOM 1066 SG CYS A 140 12.046 17.995 32.570 1.00 17.08 S ATOM 1067 N LEU A 141 9.983 17.910 36.071 1.00 15.52 N ATOM 1068 CA LEU A 141 9.555 19.031 36.887 1.00 16.29 C ATOM 1069 C LEU A 141 10.312 19.095 38.192 1.00 15.49 C ATOM 1070 O LEU A 141 10.869 20.094 38.642 1.00 17.43 O ATOM 1071 CB LEU A 141 8.025 18.985 37.159 1.00 17.86 C ATOM 1072 CG LEU A 141 7.487 19.831 38.291 1.00 24.25 C ATOM 1073 CD1 LEU A 141 7.772 21.295 38.177 1.00 28.00 C ATOM 1074 CD2 LEU A 141 5.925 19.512 38.164 1.00 26.57 C ATOM 1075 N PHE A 142 10.248 17.991 38.985 1.00 14.72 N ATOM 1076 CA PHE A 142 10.896 18.031 40.253 1.00 15.33 C ATOM 1077 C PHE A 142 12.408 18.044 40.290 1.00 13.85 C ATOM 1078 O PHE A 142 13.055 18.587 41.143 1.00 15.25 O ATOM 1079 CB PHE A 142 10.309 16.889 41.243 1.00 15.66 C ATOM 1080 CG PHE A 142 8.841 17.184 41.650 1.00 14.77 C ATOM 1081 CD1 PHE A 142 7.821 16.595 40.947 1.00 19.78 C ATOM 1082 CD2 PHE A 142 8.580 18.137 42.625 1.00 19.31 C ATOM 1083 CE1 PHE A 142 6.468 16.910 41.263 1.00 20.65 C ATOM 1084 CE2 PHE A 142 7.227 18.464 42.965 1.00 15.44 C ATOM 1085 CZ PHE A 142 6.227 17.830 42.290 1.00 17.78 C ATOM 1086 N SER A 143 12.995 17.377 39.289 1.00 15.08 N ATOM 1087 CA SER A 143 14.432 17.430 39.195 1.00 14.62 C ATOM 1088 C SER A 143 14.942 18.860 38.896 1.00 12.34 C ATOM 1089 O SER A 143 15.913 19.323 39.539 1.00 14.01 O ATOM 1090 CB SER A 143 14.840 16.489 38.052 1.00 14.52 C ATOM 1091 OG SER A 143 14.642 15.073 38.344 1.00 17.56 O ATOM 1092 N PHE A 144 14.230 19.516 37.966 1.00 13.37 N ATOM 1093 CA PHE A 144 14.609 20.933 37.723 1.00 15.49 C ATOM 1094 C PHE A 144 14.284 21.932 38.839 1.00 13.42 C ATOM 1095 O PHE A 144 14.984 22.860 39.080 1.00 16.60 O ATOM 1096 CB PHE A 144 14.228 21.394 36.287 1.00 13.23 C ATOM 1097 CG PHE A 144 15.067 20.697 35.216 1.00 11.28 C ATOM 1098 CD1 PHE A 144 14.534 19.933 34.200 1.00 14.49 C ATOM 1099 CD2 PHE A 144 16.415 20.940 35.289 1.00 14.26 C ATOM 1100 CE1 PHE A 144 15.412 19.300 33.261 1.00 15.47 C ATOM 1101 CE2 PHE A 144 17.324 20.328 34.326 1.00 12.53 C ATOM 1102 CZ PHE A 144 16.803 19.526 33.349 1.00 14.37 C ATOM 1103 N ILE A 145 13.211 21.645 39.621 1.00 16.33 N ATOM 1104 CA ILE A 145 13.053 22.388 40.835 1.00 17.36 C ATOM 1105 C ILE A 145 14.278 22.250 41.713 1.00 15.75 C ATOM 1106 O ILE A 145 14.700 23.225 42.333 1.00 17.69 O ATOM 1107 CB ILE A 145 11.775 21.905 41.576 1.00 16.39 C ATOM 1108 CG1 ILE A 145 10.536 22.466 40.845 1.00 17.76 C ATOM 1109 CG2 ILE A 145 11.796 22.434 43.052 1.00 19.97 C ATOM 1110 CD1 ILE A 145 9.102 22.134 41.531 1.00 19.45 C ATOM 1111 N CYS A 146 14.871 21.037 41.819 1.00 15.09 N ATOM 1112 CA CYS A 146 16.065 20.845 42.615 1.00 15.92 C ATOM 1113 C CYS A 146 17.335 21.487 42.039 1.00 15.26 C ATOM 1114 O CYS A 146 18.340 21.597 42.724 1.00 16.44 O ATOM 1115 CB CYS A 146 16.433 19.348 42.712 1.00 13.64 C ATOM 1116 SG CYS A 146 15.199 18.486 43.835 1.00 19.87 S ATOM 1117 N SER A 147 17.256 21.893 40.773 1.00 15.74 N ATOM 1118 CA SER A 147 18.432 22.387 40.026 1.00 17.37 C ATOM 1119 C SER A 147 18.725 23.852 40.182 1.00 17.90 C ATOM 1120 O SER A 147 19.841 24.295 39.866 1.00 18.18 O ATOM 1121 CB SER A 147 18.294 22.120 38.525 1.00 14.15 C ATOM 1122 OG SER A 147 17.363 23.024 37.865 1.00 15.09 O ATOM 1123 N SER A 148 17.787 24.633 40.720 1.00 18.29 N ATOM 1124 CA SER A 148 17.965 26.112 40.671 1.00 18.00 C ATOM 1125 C SER A 148 19.081 26.580 41.606 1.00 19.67 C ATOM 1126 O SER A 148 19.295 26.055 42.732 1.00 18.09 O ATOM 1127 CB SER A 148 16.636 26.811 40.942 1.00 20.31 C ATOM 1128 OG SER A 148 16.409 26.642 42.341 1.00 19.53 O ATOM 1129 N ASN A 149 19.883 27.543 41.144 1.00 19.55 N ATOM 1130 CA ASN A 149 20.974 28.067 41.956 1.00 18.71 C ATOM 1131 C ASN A 149 21.885 26.985 42.609 1.00 19.17 C ATOM 1132 O ASN A 149 22.053 26.881 43.865 1.00 18.29 O ATOM 1133 CB ASN A 149 20.364 28.979 43.044 1.00 19.41 C ATOM 1134 CG ASN A 149 21.403 29.807 43.743 1.00 22.75 C ATOM 1135 OD1 ASN A 149 22.445 30.193 43.160 1.00 23.56 O ATOM 1136 ND2 ASN A 149 21.125 30.133 45.054 1.00 20.48 N ATOM 1137 N ASN A 150 22.424 26.112 41.753 1.00 18.22 N ATOM 1138 CA ASN A 150 22.983 24.855 42.225 1.00 17.85 C ATOM 1139 C ASN A 150 23.863 24.321 41.120 1.00 18.82 C ATOM 1140 O ASN A 150 23.784 24.776 39.994 1.00 17.87 O ATOM 1141 CB ASN A 150 21.836 23.863 42.524 1.00 18.12 C ATOM 1142 CG ASN A 150 22.213 22.781 43.544 1.00 20.24 C ATOM 1143 OD1 ASN A 150 23.345 22.581 43.944 1.00 20.33 O ATOM 1144 ND2 ASN A 150 21.160 22.038 43.951 1.00 17.88 N ATOM 1145 N ASN A 151 24.616 23.291 41.428 1.00 16.67 N ATOM 1146 CA ASN A 151 25.482 22.639 40.460 1.00 15.19 C ATOM 1147 C ASN A 151 25.148 21.181 40.176 1.00 17.64 C ATOM 1148 O ASN A 151 24.633 20.449 41.047 1.00 17.59 O ATOM 1149 CB ASN A 151 26.970 22.808 40.898 1.00 15.85 C ATOM 1150 CG ASN A 151 27.297 22.055 42.256 1.00 15.59 C ATOM 1151 OD1 ASN A 151 27.495 20.787 42.309 1.00 19.60 O ATOM 1152 ND2 ASN A 151 27.279 22.874 43.310 1.00 19.36 N ATOM 1153 N ILE A 152 25.423 20.698 38.970 1.00 14.66 N ATOM 1154 CA ILE A 152 24.976 19.356 38.527 1.00 15.26 C ATOM 1155 C ILE A 152 25.408 18.226 39.512 1.00 14.75 C ATOM 1156 O ILE A 152 24.632 17.349 39.787 1.00 17.24 O ATOM 1157 CB ILE A 152 25.443 19.058 37.045 1.00 15.71 C ATOM 1158 CG1 ILE A 152 24.685 19.978 36.113 1.00 16.97 C ATOM 1159 CG2 ILE A 152 25.217 17.654 36.624 1.00 16.29 C ATOM 1160 CD1 ILE A 152 25.368 20.127 34.737 1.00 16.49 C ATOM 1161 N ALA A 153 26.641 18.267 40.038 1.00 15.92 N ATOM 1162 CA ALA A 153 27.086 17.138 40.901 1.00 15.42 C ATOM 1163 C ALA A 153 26.166 17.108 42.157 1.00 15.57 C ATOM 1164 O ALA A 153 25.667 16.012 42.487 1.00 18.44 O ATOM 1165 CB ALA A 153 28.543 17.376 41.375 1.00 16.83 C ATOM 1166 N ARG A 154 25.952 18.296 42.720 1.00 16.35 N ATOM 1167 CA ARG A 154 25.024 18.322 43.936 1.00 16.51 C ATOM 1168 C ARG A 154 23.620 17.928 43.589 1.00 17.12 C ATOM 1169 O ARG A 154 22.957 17.098 44.304 1.00 16.95 O ATOM 1170 CB ARG A 154 25.066 19.656 44.656 1.00 16.33 C ATOM 1171 CG ARG A 154 24.029 19.766 45.819 1.00 19.30 C ATOM 1172 CD ARG A 154 24.395 20.939 46.701 1.00 17.28 C ATOM 1173 NE ARG A 154 23.247 21.029 47.624 1.00 19.21 N ATOM 1174 CZ ARG A 154 22.452 22.082 47.810 1.00 18.86 C ATOM 1175 NH1 ARG A 154 21.384 21.937 48.614 1.00 20.80 N ATOM 1176 NH2 ARG A 154 22.710 23.281 47.250 1.00 20.36 N ATOM 1177 N ILE A 155 23.068 18.541 42.531 1.00 17.24 N ATOM 1178 CA ILE A 155 21.725 18.195 42.101 1.00 15.20 C ATOM 1179 C ILE A 155 21.565 16.673 41.915 1.00 14.96 C ATOM 1180 O ILE A 155 20.540 16.102 42.300 1.00 16.19 O ATOM 1181 CB ILE A 155 21.377 18.882 40.727 1.00 15.09 C ATOM 1182 CG1 ILE A 155 21.621 20.361 40.874 1.00 15.72 C ATOM 1183 CG2 ILE A 155 19.982 18.397 40.287 1.00 14.09 C ATOM 1184 CD1 ILE A 155 21.740 21.074 39.547 1.00 17.56 C ATOM 1185 N THR A 156 22.564 15.997 41.248 1.00 15.10 N ATOM 1186 CA THR A 156 22.516 14.569 41.052 1.00 15.25 C ATOM 1187 C THR A 156 22.347 13.762 42.363 1.00 14.42 C ATOM 1188 O THR A 156 21.525 12.901 42.415 1.00 15.15 O ATOM 1189 CB THR A 156 23.819 14.091 40.312 1.00 16.81 C ATOM 1190 OG1 THR A 156 23.839 14.803 39.030 1.00 15.56 O ATOM 1191 CG2 THR A 156 23.668 12.686 40.031 1.00 18.68 C ATOM 1192 N GLY A 157 23.142 14.126 43.352 1.00 16.40 N ATOM 1193 CA GLY A 157 22.969 13.501 44.687 1.00 17.12 C ATOM 1194 C GLY A 157 21.621 13.794 45.323 1.00 17.98 C ATOM 1195 O GLY A 157 21.004 12.861 45.856 1.00 17.31 O ATOM 1196 N MET A 158 21.137 15.031 45.254 1.00 16.70 N ATOM 1197 CA MET A 158 19.792 15.368 45.792 1.00 16.23 C ATOM 1198 C MET A 158 18.652 14.546 45.168 1.00 19.09 C ATOM 1199 O MET A 158 17.776 13.962 45.862 1.00 18.69 O ATOM 1200 CB MET A 158 19.485 16.906 45.577 1.00 15.82 C ATOM 1201 CG MET A 158 20.227 17.764 46.522 1.00 16.82 C ATOM 1202 SD MET A 158 20.314 19.465 46.021 1.00 21.09 S ATOM 1203 CE MET A 158 18.610 19.986 45.821 1.00 19.11 C ATOM 1204 N VAL A 159 18.678 14.385 43.851 1.00 16.08 N ATOM 1205 CA VAL A 159 17.716 13.600 43.152 1.00 17.21 C ATOM 1206 C VAL A 159 17.773 12.091 43.549 1.00 18.30 C ATOM 1207 O VAL A 159 16.744 11.430 43.702 1.00 18.67 O ATOM 1208 CB VAL A 159 17.884 13.804 41.652 1.00 17.54 C ATOM 1209 CG1 VAL A 159 16.992 12.811 40.861 1.00 18.32 C ATOM 1210 CG2 VAL A 159 17.516 15.256 41.348 1.00 19.17 C ATOM 1211 N GLU A 160 18.995 11.570 43.700 1.00 18.90 N ATOM 1212 CA GLU A 160 19.214 10.189 44.065 1.00 18.73 C ATOM 1213 C GLU A 160 18.596 9.933 45.448 1.00 17.29 C ATOM 1214 O GLU A 160 17.855 9.009 45.598 1.00 17.72 O ATOM 1215 CB GLU A 160 20.700 9.844 44.092 1.00 19.76 C ATOM 1216 CG GLU A 160 21.124 9.187 42.750 1.00 24.02 C ATOM 1217 CD GLU A 160 22.632 9.211 42.494 1.00 30.95 C ATOM 1218 OE1 GLU A 160 23.029 9.006 41.283 1.00 27.95 O ATOM 1219 OE2 GLU A 160 23.412 9.406 43.483 1.00 29.37 O ATOM 1220 N ARG A 161 18.805 10.905 46.308 1.00 19.42 N ATOM 1221 CA ARG A 161 18.418 10.704 47.737 1.00 17.85 C ATOM 1222 C ARG A 161 16.944 10.905 47.824 1.00 19.20 C ATOM 1223 O ARG A 161 16.248 10.204 48.577 1.00 18.87 O ATOM 1224 CB ARG A 161 19.169 11.664 48.664 1.00 17.52 C ATOM 1225 CG ARG A 161 20.663 11.313 48.863 1.00 18.34 C ATOM 1226 CD ARG A 161 21.374 12.149 49.911 1.00 17.02 C ATOM 1227 NE ARG A 161 21.270 13.573 49.775 1.00 18.44 N ATOM 1228 CZ ARG A 161 22.103 14.303 49.003 1.00 23.11 C ATOM 1229 NH1 ARG A 161 23.091 13.700 48.308 1.00 20.14 N ATOM 1230 NH2 ARG A 161 21.940 15.599 48.930 1.00 22.55 N ATOM 1231 N LEU A 162 16.403 11.818 47.032 1.00 19.02 N ATOM 1232 CA LEU A 162 14.946 11.953 46.889 1.00 18.45 C ATOM 1233 C LEU A 162 14.274 10.665 46.422 1.00 19.70 C ATOM 1234 O LEU A 162 13.204 10.272 46.980 1.00 19.73 O ATOM 1235 CB LEU A 162 14.634 13.156 45.974 1.00 19.83 C ATOM 1236 CG LEU A 162 13.178 13.497 45.629 1.00 21.96 C ATOM 1237 CD1 LEU A 162 12.956 15.087 45.582 1.00 28.04 C ATOM 1238 CD2 LEU A 162 12.717 12.873 44.451 1.00 24.46 C ATOM 1239 N CYS A 163 14.838 9.998 45.383 1.00 17.82 N ATOM 1240 CA CYS A 163 14.217 8.812 44.862 1.00 17.21 C ATOM 1241 C CYS A 163 14.377 7.688 45.877 1.00 16.33 C ATOM 1242 O CYS A 163 13.473 6.823 45.944 1.00 17.33 O ATOM 1243 CB CYS A 163 14.809 8.413 43.473 1.00 16.76 C ATOM 1244 SG CYS A 163 14.406 9.652 42.166 1.00 17.60 S ATOM 1245 N GLN A 164 15.503 7.660 46.570 1.00 18.82 N ATOM 1246 CA GLN A 164 15.730 6.552 47.556 1.00 20.71 C ATOM 1247 C GLN A 164 14.666 6.664 48.666 1.00 22.77 C ATOM 1248 O GLN A 164 14.047 5.662 49.063 1.00 22.81 O ATOM 1249 CB GLN A 164 17.107 6.599 48.128 1.00 22.35 C ATOM 1250 CG GLN A 164 17.267 5.439 49.129 1.00 28.17 C ATOM 1251 CD GLN A 164 18.612 5.339 49.739 1.00 39.23 C ATOM 1252 OE1 GLN A 164 19.593 5.900 49.241 1.00 46.07 O ATOM 1253 NE2 GLN A 164 18.678 4.629 50.872 1.00 44.63 N ATOM 1254 N ALA A 165 14.454 7.886 49.128 1.00 22.98 N ATOM 1255 CA ALA A 165 13.501 8.083 50.294 1.00 22.38 C ATOM 1256 C ALA A 165 12.027 7.964 49.921 1.00 22.48 C ATOM 1257 O ALA A 165 11.178 7.552 50.768 1.00 23.14 O ATOM 1258 CB ALA A 165 13.813 9.432 50.987 1.00 24.11 C ATOM 1259 N PHE A 166 11.637 8.282 48.681 1.00 20.43 N ATOM 1260 CA PHE A 166 10.238 8.455 48.342 1.00 19.11 C ATOM 1261 C PHE A 166 9.748 7.674 47.180 1.00 18.69 C ATOM 1262 O PHE A 166 8.586 7.651 46.909 1.00 21.98 O ATOM 1263 CB PHE A 166 9.869 9.953 48.203 1.00 21.05 C ATOM 1264 CG PHE A 166 9.969 10.678 49.494 1.00 19.72 C ATOM 1265 CD1 PHE A 166 11.058 11.495 49.813 1.00 22.46 C ATOM 1266 CD2 PHE A 166 8.987 10.416 50.486 1.00 25.02 C ATOM 1267 CE1 PHE A 166 11.221 12.102 51.076 1.00 26.29 C ATOM 1268 CE2 PHE A 166 9.106 11.054 51.736 1.00 26.57 C ATOM 1269 CZ PHE A 166 10.185 11.861 52.050 1.00 25.70 C ATOM 1270 N GLY A 167 10.686 7.097 46.387 1.00 17.92 N ATOM 1271 CA GLY A 167 10.348 6.284 45.209 1.00 16.19 C ATOM 1272 C GLY A 167 10.384 4.765 45.454 1.00 14.37 C ATOM 1273 O GLY A 167 11.168 4.317 46.341 1.00 16.22 O ATOM 1274 N PRO A 168 9.694 3.985 44.587 1.00 17.45 N ATOM 1275 CA PRO A 168 9.650 2.523 44.768 1.00 17.90 C ATOM 1276 C PRO A 168 10.985 1.872 44.440 1.00 18.51 C ATOM 1277 O PRO A 168 11.650 2.288 43.469 1.00 16.57 O ATOM 1278 CB PRO A 168 8.581 2.056 43.774 1.00 20.42 C ATOM 1279 CG PRO A 168 8.505 3.130 42.763 1.00 20.18 C ATOM 1280 CD PRO A 168 8.872 4.424 43.446 1.00 19.19 C ATOM 1281 N ARG A 169 11.449 0.938 45.278 1.00 16.59 N ATOM 1282 CA ARG A 169 12.612 0.190 44.996 1.00 15.82 C ATOM 1283 C ARG A 169 12.409 -0.660 43.772 1.00 17.90 C ATOM 1284 O ARG A 169 11.384 -1.312 43.617 1.00 16.75 O ATOM 1285 CB ARG A 169 12.902 -0.780 46.211 1.00 15.97 C ATOM 1286 CG ARG A 169 14.315 -1.267 46.253 1.00 21.72 C ATOM 1287 CD ARG A 169 14.499 -2.386 47.401 1.00 24.04 C ATOM 1288 NE ARG A 169 14.229 -3.511 46.607 1.00 34.74 N ATOM 1289 CZ ARG A 169 15.108 -4.297 45.984 1.00 28.58 C ATOM 1290 NH1 ARG A 169 14.602 -5.194 45.185 1.00 31.23 N ATOM 1291 NH2 ARG A 169 16.396 -4.243 46.201 1.00 29.97 N ATOM 1292 N LEU A 170 13.411 -0.622 42.874 1.00 13.61 N ATOM 1293 CA LEU A 170 13.346 -1.426 41.712 1.00 13.19 C ATOM 1294 C LEU A 170 14.236 -2.661 41.745 1.00 15.72 C ATOM 1295 O LEU A 170 13.735 -3.793 41.711 1.00 19.30 O ATOM 1296 CB LEU A 170 13.644 -0.579 40.467 1.00 13.15 C ATOM 1297 CG LEU A 170 12.680 0.636 40.249 1.00 13.57 C ATOM 1298 CD1 LEU A 170 13.222 1.422 38.977 1.00 16.27 C ATOM 1299 CD2 LEU A 170 11.139 0.267 40.081 1.00 16.11 C ATOM 1300 N ILE A 171 15.542 -2.444 41.746 1.00 15.26 N ATOM 1301 CA ILE A 171 16.472 -3.573 41.814 1.00 18.80 C ATOM 1302 C ILE A 171 17.781 -3.026 42.368 1.00 17.54 C ATOM 1303 O ILE A 171 18.024 -1.822 42.372 1.00 17.71 O ATOM 1304 CB ILE A 171 16.824 -4.257 40.508 1.00 19.70 C ATOM 1305 CG1 ILE A 171 17.480 -3.221 39.629 1.00 22.04 C ATOM 1306 CG2 ILE A 171 15.622 -4.920 39.774 1.00 27.47 C ATOM 1307 CD1 ILE A 171 18.633 -3.767 38.956 1.00 25.75 C ATOM 1308 N GLN A 172 18.648 -3.949 42.812 1.00 14.60 N ATOM 1309 CA GLN A 172 19.944 -3.610 43.363 1.00 13.52 C ATOM 1310 C GLN A 172 21.002 -4.350 42.519 1.00 13.94 C ATOM 1311 O GLN A 172 20.917 -5.557 42.274 1.00 14.67 O ATOM 1312 CB GLN A 172 20.035 -4.183 44.828 1.00 13.72 C ATOM 1313 CG GLN A 172 21.349 -3.821 45.466 1.00 16.07 C ATOM 1314 CD GLN A 172 21.561 -4.560 46.779 1.00 17.37 C ATOM 1315 OE1 GLN A 172 20.591 -4.742 47.500 1.00 17.75 O ATOM 1316 NE2 GLN A 172 22.753 -5.075 47.020 1.00 16.93 N ATOM 1317 N LEU A 173 22.010 -3.568 42.104 1.00 14.09 N ATOM 1318 CA LEU A 173 23.180 -4.106 41.361 1.00 14.09 C ATOM 1319 C LEU A 173 24.398 -3.671 42.092 1.00 11.91 C ATOM 1320 O LEU A 173 24.558 -2.483 42.404 1.00 14.10 O ATOM 1321 CB LEU A 173 23.187 -3.438 39.926 1.00 15.32 C ATOM 1322 CG LEU A 173 21.971 -3.888 39.122 1.00 15.94 C ATOM 1323 CD1 LEU A 173 22.040 -3.022 37.794 1.00 15.46 C ATOM 1324 CD2 LEU A 173 21.988 -5.318 38.795 1.00 16.72 C ATOM 1325 N ASP A 174 25.268 -4.659 42.402 1.00 14.46 N ATOM 1326 CA ASP A 174 26.392 -4.366 43.313 1.00 15.11 C ATOM 1327 C ASP A 174 25.852 -3.727 44.584 1.00 15.79 C ATOM 1328 O ASP A 174 24.903 -4.345 45.126 1.00 16.01 O ATOM 1329 CB ASP A 174 27.454 -3.442 42.664 1.00 15.88 C ATOM 1330 CG ASP A 174 28.166 -4.131 41.505 1.00 22.66 C ATOM 1331 OD1 ASP A 174 28.739 -5.228 41.703 1.00 22.04 O ATOM 1332 OD2 ASP A 174 28.082 -3.600 40.329 1.00 20.41 O ATOM 1333 N ASP A 175 26.368 -2.614 45.040 1.00 16.08 N ATOM 1334 CA ASP A 175 25.839 -1.890 46.231 1.00 14.99 C ATOM 1335 C ASP A 175 24.899 -0.753 45.913 1.00 16.66 C ATOM 1336 O ASP A 175 24.632 0.147 46.745 1.00 16.77 O ATOM 1337 CB ASP A 175 27.007 -1.498 47.217 1.00 16.07 C ATOM 1338 CG ASP A 175 28.069 -0.636 46.555 1.00 19.70 C ATOM 1339 OD1 ASP A 175 27.927 -0.296 45.363 1.00 21.69 O ATOM 1340 OD2 ASP A 175 28.998 -0.195 47.218 1.00 19.26 O ATOM 1341 N VAL A 176 24.439 -0.705 44.648 1.00 14.65 N ATOM 1342 CA VAL A 176 23.572 0.388 44.216 1.00 15.51 C ATOM 1343 C VAL A 176 22.114 -0.044 44.097 1.00 12.36 C ATOM 1344 O VAL A 176 21.789 -0.986 43.406 1.00 14.11 O ATOM 1345 CB VAL A 176 24.044 0.863 42.813 1.00 16.14 C ATOM 1346 CG1 VAL A 176 23.168 2.066 42.360 1.00 17.18 C ATOM 1347 CG2 VAL A 176 25.515 1.350 42.887 1.00 18.02 C ATOM 1348 N THR A 177 21.225 0.635 44.829 1.00 13.50 N ATOM 1349 CA THR A 177 19.822 0.315 44.725 1.00 13.53 C ATOM 1350 C THR A 177 19.172 1.387 43.842 1.00 14.26 C ATOM 1351 O THR A 177 19.270 2.598 44.130 1.00 16.78 O ATOM 1352 CB THR A 177 19.098 0.215 46.084 1.00 15.17 C ATOM 1353 OG1 THR A 177 19.818 -0.761 46.868 1.00 17.77 O ATOM 1354 CG2 THR A 177 17.643 -0.285 45.880 1.00 14.69 C ATOM 1355 N TYR A 178 18.461 0.923 42.819 1.00 14.17 N ATOM 1356 CA TYR A 178 17.758 1.902 41.970 1.00 14.48 C ATOM 1357 C TYR A 178 16.346 2.014 42.384 1.00 13.50 C ATOM 1358 O TYR A 178 15.708 0.979 42.740 1.00 14.43 O ATOM 1359 CB TYR A 178 17.807 1.365 40.501 1.00 14.29 C ATOM 1360 CG TYR A 178 19.199 1.392 39.959 1.00 13.77 C ATOM 1361 CD1 TYR A 178 20.064 0.325 40.166 1.00 14.22 C ATOM 1362 CD2 TYR A 178 19.630 2.500 39.234 1.00 15.84 C ATOM 1363 CE1 TYR A 178 21.402 0.373 39.695 1.00 16.10 C ATOM 1364 CE2 TYR A 178 20.971 2.551 38.761 1.00 17.41 C ATOM 1365 CZ TYR A 178 21.821 1.487 38.998 1.00 14.68 C ATOM 1366 OH TYR A 178 23.116 1.622 38.542 1.00 16.82 O ATOM 1367 N HIS A 179 15.843 3.261 42.328 1.00 13.15 N ATOM 1368 CA HIS A 179 14.439 3.522 42.669 1.00 13.64 C ATOM 1369 C HIS A 179 13.743 4.264 41.528 1.00 14.80 C ATOM 1370 O HIS A 179 14.368 5.065 40.810 1.00 14.96 O ATOM 1371 CB HIS A 179 14.393 4.450 43.921 1.00 14.33 C ATOM 1372 CG HIS A 179 14.775 3.762 45.214 1.00 15.97 C ATOM 1373 ND1 HIS A 179 13.822 3.442 46.165 1.00 16.62 N ATOM 1374 CD2 HIS A 179 15.973 3.369 45.713 1.00 15.92 C ATOM 1375 CE1 HIS A 179 14.431 2.837 47.184 1.00 18.57 C ATOM 1376 NE2 HIS A 179 15.722 2.767 46.940 1.00 16.96 N ATOM 1377 N GLY A 180 12.422 4.063 41.439 1.00 15.69 N ATOM 1378 CA GLY A 180 11.576 4.869 40.511 1.00 14.86 C ATOM 1379 C GLY A 180 11.457 6.285 41.039 1.00 14.91 C ATOM 1380 O GLY A 180 11.749 6.565 42.207 1.00 15.20 O ATOM 1381 N PHE A 181 11.118 7.208 40.111 1.00 15.79 N ATOM 1382 CA PHE A 181 10.878 8.578 40.570 1.00 15.23 C ATOM 1383 C PHE A 181 9.608 8.612 41.475 1.00 15.63 C ATOM 1384 O PHE A 181 8.665 7.959 41.136 1.00 15.55 O ATOM 1385 CB PHE A 181 10.783 9.592 39.381 1.00 15.75 C ATOM 1386 CG PHE A 181 11.064 10.936 39.794 1.00 14.32 C ATOM 1387 CD1 PHE A 181 12.394 11.390 39.867 1.00 16.66 C ATOM 1388 CD2 PHE A 181 10.074 11.845 40.209 1.00 15.45 C ATOM 1389 CE1 PHE A 181 12.713 12.624 40.350 1.00 16.21 C ATOM 1390 CE2 PHE A 181 10.424 13.138 40.693 1.00 15.71 C ATOM 1391 CZ PHE A 181 11.713 13.550 40.820 1.00 16.85 C ATOM 1392 N PRO A 182 9.638 9.416 42.541 1.00 16.87 N ATOM 1393 CA PRO A 182 8.424 9.490 43.416 1.00 17.76 C ATOM 1394 C PRO A 182 7.152 9.962 42.707 1.00 21.16 C ATOM 1395 O PRO A 182 7.203 10.807 41.768 1.00 20.62 O ATOM 1396 CB PRO A 182 8.837 10.503 44.465 1.00 19.24 C ATOM 1397 CG PRO A 182 10.307 10.293 44.627 1.00 17.50 C ATOM 1398 CD PRO A 182 10.778 10.103 43.157 1.00 16.46 C ATOM 1399 N SER A 183 5.992 9.422 43.121 1.00 20.18 N ATOM 1400 CA SER A 183 4.693 9.929 42.687 1.00 20.53 C ATOM 1401 C SER A 183 4.418 11.316 43.367 1.00 17.71 C ATOM 1402 O SER A 183 5.003 11.694 44.375 1.00 18.54 O ATOM 1403 CB SER A 183 3.564 8.938 43.085 1.00 21.63 C ATOM 1404 OG SER A 183 3.460 8.959 44.488 1.00 22.60 O ATOM 1405 N LEU A 184 3.529 12.090 42.747 1.00 22.07 N ATOM 1406 CA LEU A 184 2.933 13.285 43.420 1.00 24.15 C ATOM 1407 C LEU A 184 2.396 13.040 44.850 1.00 23.68 C ATOM 1408 O LEU A 184 2.685 13.823 45.809 1.00 25.54 O ATOM 1409 CB LEU A 184 1.743 13.700 42.577 1.00 26.23 C ATOM 1410 CG LEU A 184 1.616 14.938 41.706 1.00 32.08 C ATOM 1411 CD1 LEU A 184 2.905 15.729 41.600 1.00 28.76 C ATOM 1412 CD2 LEU A 184 0.921 14.616 40.398 1.00 29.50 C ATOM 1413 N GLN A 185 1.690 11.916 44.993 1.00 25.89 N ATOM 1414 CA GLN A 185 1.208 11.523 46.313 1.00 25.07 C ATOM 1415 C GLN A 185 2.302 11.411 47.334 1.00 23.06 C ATOM 1416 O GLN A 185 2.189 11.938 48.435 1.00 23.86 O ATOM 1417 CB GLN A 185 0.436 10.194 46.256 1.00 27.13 C ATOM 1418 CG GLN A 185 -0.938 10.299 45.627 1.00 32.11 C ATOM 1419 CD GLN A 185 -0.963 10.477 44.113 1.00 39.55 C ATOM 1420 OE1 GLN A 185 -1.989 10.950 43.564 1.00 41.17 O ATOM 1421 NE2 GLN A 185 0.119 10.081 43.411 1.00 39.30 N ATOM 1422 N ALA A 186 3.415 10.711 47.000 1.00 20.34 N ATOM 1423 CA ALA A 186 4.471 10.601 47.949 1.00 21.97 C ATOM 1424 C ALA A 186 5.060 11.980 48.297 1.00 22.10 C ATOM 1425 O ALA A 186 5.454 12.271 49.401 1.00 22.13 O ATOM 1426 CB ALA A 186 5.563 9.650 47.372 1.00 19.67 C ATOM 1427 N LEU A 187 5.203 12.799 47.262 1.00 23.57 N ATOM 1428 CA LEU A 187 5.877 14.052 47.443 1.00 22.36 C ATOM 1429 C LEU A 187 5.052 15.089 48.219 1.00 22.51 C ATOM 1430 O LEU A 187 5.627 15.905 48.980 1.00 22.53 O ATOM 1431 CB LEU A 187 6.260 14.585 46.010 1.00 21.32 C ATOM 1432 CG LEU A 187 7.400 13.759 45.344 1.00 18.06 C ATOM 1433 CD1 LEU A 187 7.807 14.404 44.024 1.00 24.64 C ATOM 1434 CD2 LEU A 187 8.520 13.776 46.210 1.00 18.79 C ATOM 1435 N ALA A 188 3.744 14.922 48.045 1.00 23.13 N ATOM 1436 CA ALA A 188 2.701 15.739 48.712 1.00 24.63 C ATOM 1437 C ALA A 188 2.417 15.270 50.117 1.00 26.96 C ATOM 1438 O ALA A 188 1.609 15.920 50.825 1.00 28.80 O ATOM 1439 CB ALA A 188 1.486 15.722 47.946 1.00 22.77 C ATOM 1440 N GLY A 189 3.050 14.181 50.547 1.00 26.69 N ATOM 1441 CA GLY A 189 2.683 13.633 51.896 1.00 28.17 C ATOM 1442 C GLY A 189 3.183 14.389 53.097 1.00 28.38 C ATOM 1443 O GLY A 189 4.028 15.303 53.029 1.00 28.24 O ATOM 1444 N PRO A 190 2.665 14.003 54.269 1.00 27.78 N ATOM 1445 CA PRO A 190 3.107 14.667 55.473 1.00 28.52 C ATOM 1446 C PRO A 190 4.588 14.561 55.784 1.00 28.32 C ATOM 1447 O PRO A 190 5.181 13.499 55.616 1.00 30.22 O ATOM 1448 CB PRO A 190 2.320 13.943 56.608 1.00 28.65 C ATOM 1449 CG PRO A 190 1.458 12.925 55.962 1.00 29.62 C ATOM 1450 CD PRO A 190 1.762 12.849 54.494 1.00 29.94 C ATOM 1451 N GLU A 191 5.146 15.645 56.304 1.00 28.50 N ATOM 1452 CA GLU A 191 6.480 15.747 56.836 1.00 27.59 C ATOM 1453 C GLU A 191 7.584 15.601 55.746 1.00 27.64 C ATOM 1454 O GLU A 191 8.732 15.456 56.097 1.00 28.86 O ATOM 1455 CB GLU A 191 6.681 14.763 57.990 1.00 29.39 C ATOM 1456 CG GLU A 191 5.924 15.235 59.295 1.00 32.56 C ATOM 1457 CD GLU A 191 6.089 14.289 60.450 1.00 40.30 C ATOM 1458 OE1 GLU A 191 7.007 14.528 61.278 1.00 44.73 O ATOM 1459 OE2 GLU A 191 5.315 13.302 60.522 1.00 42.02 O ATOM 1460 N VAL A 192 7.177 15.631 54.489 1.00 26.38 N ATOM 1461 CA VAL A 192 8.127 15.435 53.348 1.00 26.92 C ATOM 1462 C VAL A 192 9.184 16.548 53.359 1.00 26.99 C ATOM 1463 O VAL A 192 10.393 16.268 53.216 1.00 26.02 O ATOM 1464 CB VAL A 192 7.424 15.386 51.994 1.00 25.85 C ATOM 1465 CG1 VAL A 192 8.451 15.458 50.790 1.00 27.26 C ATOM 1466 CG2 VAL A 192 6.642 14.083 51.838 1.00 28.06 C ATOM 1467 N GLU A 193 8.758 17.809 53.532 1.00 26.45 N ATOM 1468 CA GLU A 193 9.734 18.931 53.618 1.00 24.60 C ATOM 1469 C GLU A 193 10.828 18.727 54.649 1.00 25.15 C ATOM 1470 O GLU A 193 12.027 18.842 54.379 1.00 22.83 O ATOM 1471 CB GLU A 193 9.052 20.321 53.836 1.00 23.58 C ATOM 1472 CG GLU A 193 10.050 21.441 54.071 1.00 28.13 C ATOM 1473 CD GLU A 193 9.403 22.817 54.347 1.00 34.36 C ATOM 1474 OE1 GLU A 193 10.166 23.753 54.623 1.00 38.04 O ATOM 1475 OE2 GLU A 193 8.165 22.940 54.261 1.00 36.22 O ATOM 1476 N ALA A 194 10.447 18.354 55.885 1.00 21.90 N ATOM 1477 CA ALA A 194 11.438 18.103 56.865 1.00 23.38 C ATOM 1478 C ALA A 194 12.505 17.020 56.482 1.00 21.47 C ATOM 1479 O ALA A 194 13.663 17.140 56.857 1.00 22.50 O ATOM 1480 CB ALA A 194 10.738 17.660 58.212 1.00 25.19 C ATOM 1481 N HIS A 195 11.990 15.952 55.904 1.00 22.92 N ATOM 1482 CA HIS A 195 12.808 14.789 55.531 1.00 22.47 C ATOM 1483 C HIS A 195 13.742 15.236 54.363 1.00 21.66 C ATOM 1484 O HIS A 195 14.936 15.008 54.406 1.00 21.01 O ATOM 1485 CB HIS A 195 11.930 13.594 55.159 1.00 23.94 C ATOM 1486 CG HIS A 195 12.711 12.303 55.044 1.00 26.87 C ATOM 1487 ND1 HIS A 195 12.103 11.079 54.881 1.00 29.19 N ATOM 1488 CD2 HIS A 195 14.047 12.054 55.090 1.00 25.63 C ATOM 1489 CE1 HIS A 195 13.021 10.141 54.753 1.00 29.11 C ATOM 1490 NE2 HIS A 195 14.207 10.702 54.886 1.00 29.42 N ATOM 1491 N LEU A 196 13.178 16.002 53.464 1.00 22.48 N ATOM 1492 CA LEU A 196 14.031 16.560 52.383 1.00 21.60 C ATOM 1493 C LEU A 196 15.089 17.507 52.877 1.00 23.00 C ATOM 1494 O LEU A 196 16.188 17.528 52.337 1.00 20.22 O ATOM 1495 CB LEU A 196 13.192 17.142 51.259 1.00 21.50 C ATOM 1496 CG LEU A 196 12.338 16.205 50.404 1.00 19.77 C ATOM 1497 CD1 LEU A 196 11.383 16.906 49.393 1.00 23.70 C ATOM 1498 CD2 LEU A 196 13.102 15.014 49.694 1.00 26.82 C ATOM 1499 N ARG A 197 14.816 18.287 53.944 1.00 20.78 N ATOM 1500 CA ARG A 197 15.886 19.071 54.563 1.00 21.64 C ATOM 1501 C ARG A 197 17.000 18.226 55.074 1.00 21.00 C ATOM 1502 O ARG A 197 18.153 18.574 54.910 1.00 21.74 O ATOM 1503 CB ARG A 197 15.408 20.076 55.668 1.00 22.12 C ATOM 1504 CG ARG A 197 14.415 21.071 55.015 1.00 29.55 C ATOM 1505 CD ARG A 197 14.037 22.337 55.864 1.00 37.96 C ATOM 1506 NE ARG A 197 13.163 23.265 55.084 1.00 41.11 N ATOM 1507 CZ ARG A 197 13.587 24.367 54.420 1.00 44.02 C ATOM 1508 NH1 ARG A 197 12.691 25.080 53.739 1.00 47.16 N ATOM 1509 NH2 ARG A 197 14.887 24.780 54.433 1.00 38.68 N ATOM 1510 N LYS A 198 16.646 17.126 55.761 1.00 21.64 N ATOM 1511 CA LYS A 198 17.668 16.256 56.288 1.00 22.82 C ATOM 1512 C LYS A 198 18.424 15.571 55.169 1.00 21.40 C ATOM 1513 O LYS A 198 19.540 15.193 55.369 1.00 25.05 O ATOM 1514 CB LYS A 198 17.092 15.201 57.238 1.00 21.50 C ATOM 1515 CG LYS A 198 16.712 15.766 58.663 1.00 26.70 C ATOM 1516 CD LYS A 198 16.256 14.661 59.615 1.00 30.68 C ATOM 1517 CE LYS A 198 16.458 15.146 61.061 1.00 37.30 C ATOM 1518 NZ LYS A 198 16.304 14.055 62.061 1.00 36.30 N ATOM 1519 N LEU A 199 17.779 15.441 54.002 1.00 21.97 N ATOM 1520 CA LEU A 199 18.527 14.900 52.783 1.00 20.27 C ATOM 1521 C LEU A 199 19.326 15.988 52.029 1.00 22.47 C ATOM 1522 O LEU A 199 20.000 15.686 51.011 1.00 20.85 O ATOM 1523 CB LEU A 199 17.551 14.192 51.895 1.00 19.52 C ATOM 1524 CG LEU A 199 16.833 12.958 52.487 1.00 16.90 C ATOM 1525 CD1 LEU A 199 15.739 12.462 51.599 1.00 21.03 C ATOM 1526 CD2 LEU A 199 17.869 11.904 52.939 1.00 21.05 C ATOM 1527 N GLY A 200 19.297 17.246 52.523 1.00 20.38 N ATOM 1528 CA GLY A 200 20.301 18.244 52.061 1.00 19.49 C ATOM 1529 C GLY A 200 19.745 19.017 50.882 1.00 19.93 C ATOM 1530 O GLY A 200 20.580 19.601 50.139 1.00 19.10 O ATOM 1531 N LEU A 201 18.433 19.035 50.670 1.00 20.80 N ATOM 1532 CA LEU A 201 17.809 19.794 49.564 1.00 20.13 C ATOM 1533 C LEU A 201 17.821 21.305 49.776 1.00 21.38 C ATOM 1534 O LEU A 201 17.546 22.080 48.843 1.00 22.44 O ATOM 1535 CB LEU A 201 16.453 19.229 49.107 1.00 21.37 C ATOM 1536 CG LEU A 201 16.427 17.993 48.156 1.00 19.86 C ATOM 1537 CD1 LEU A 201 16.872 16.703 48.735 1.00 26.42 C ATOM 1538 CD2 LEU A 201 15.025 17.891 47.460 1.00 21.81 C ATOM 1539 N GLY A 202 18.133 21.736 51.006 1.00 21.40 N ATOM 1540 CA GLY A 202 18.200 23.172 51.350 1.00 21.68 C ATOM 1541 C GLY A 202 16.825 23.774 51.239 1.00 20.21 C ATOM 1542 O GLY A 202 15.807 23.087 51.407 1.00 22.50 O ATOM 1543 N TYR A 203 16.722 25.033 50.815 1.00 20.71 N ATOM 1544 CA TYR A 203 15.363 25.652 50.682 1.00 20.10 C ATOM 1545 C TYR A 203 14.458 25.103 49.612 1.00 20.28 C ATOM 1546 O TYR A 203 13.284 25.417 49.556 1.00 22.76 O ATOM 1547 CB TYR A 203 15.420 27.176 50.459 1.00 20.61 C ATOM 1548 CG TYR A 203 16.205 27.553 49.213 1.00 22.01 C ATOM 1549 CD1 TYR A 203 15.608 27.519 47.933 1.00 22.97 C ATOM 1550 CD2 TYR A 203 17.515 27.901 49.344 1.00 23.00 C ATOM 1551 CE1 TYR A 203 16.369 27.869 46.763 1.00 21.05 C ATOM 1552 CE2 TYR A 203 18.254 28.254 48.199 1.00 27.98 C ATOM 1553 CZ TYR A 203 17.668 28.227 46.968 1.00 21.69 C ATOM 1554 OH TYR A 203 18.507 28.582 45.906 1.00 23.75 O ATOM 1555 N ARG A 204 14.966 24.239 48.700 1.00 18.02 N ATOM 1556 CA ARG A 204 14.116 23.722 47.691 1.00 18.63 C ATOM 1557 C ARG A 204 13.209 22.576 48.223 1.00 18.51 C ATOM 1558 O ARG A 204 12.307 22.150 47.503 1.00 21.83 O ATOM 1559 CB ARG A 204 15.000 23.165 46.532 1.00 17.93 C ATOM 1560 CG ARG A 204 15.759 24.325 45.798 1.00 17.00 C ATOM 1561 CD ARG A 204 16.830 23.668 44.896 1.00 16.07 C ATOM 1562 NE ARG A 204 17.982 24.565 44.757 1.00 17.51 N ATOM 1563 CZ ARG A 204 18.893 24.745 45.708 1.00 18.38 C ATOM 1564 NH1 ARG A 204 19.907 25.552 45.504 1.00 20.26 N ATOM 1565 NH2 ARG A 204 18.816 24.088 46.926 1.00 21.58 N ATOM 1566 N ALA A 205 13.540 22.107 49.453 1.00 22.60 N ATOM 1567 CA ALA A 205 12.748 21.058 50.174 1.00 23.41 C ATOM 1568 C ALA A 205 11.286 21.518 50.232 1.00 22.50 C ATOM 1569 O ALA A 205 10.358 20.782 49.868 1.00 23.63 O ATOM 1570 CB ALA A 205 13.284 20.834 51.577 1.00 24.09 C ATOM 1571 N ARG A 206 11.103 22.795 50.621 1.00 23.76 N ATOM 1572 CA ARG A 206 9.747 23.371 50.609 1.00 25.86 C ATOM 1573 C ARG A 206 9.112 23.493 49.250 1.00 23.01 C ATOM 1574 O ARG A 206 7.944 23.184 49.056 1.00 24.28 O ATOM 1575 CB ARG A 206 9.752 24.740 51.312 1.00 28.15 C ATOM 1576 CG ARG A 206 8.368 25.430 51.304 1.00 32.76 C ATOM 1577 CD ARG A 206 7.928 25.914 52.738 1.00 42.83 C ATOM 1578 NE ARG A 206 8.924 26.779 53.392 1.00 48.69 N ATOM 1579 CZ ARG A 206 9.231 26.768 54.701 1.00 50.83 C ATOM 1580 NH1 ARG A 206 8.629 25.931 55.557 1.00 50.75 N ATOM 1581 NH2 ARG A 206 10.176 27.590 55.158 1.00 50.40 N ATOM 1582 N TYR A 207 9.880 23.948 48.225 1.00 22.40 N ATOM 1583 CA TYR A 207 9.306 23.955 46.910 1.00 21.64 C ATOM 1584 C TYR A 207 8.793 22.615 46.385 1.00 18.45 C ATOM 1585 O TYR A 207 7.835 22.576 45.678 1.00 20.16 O ATOM 1586 CB TYR A 207 10.343 24.433 45.834 1.00 21.06 C ATOM 1587 CG TYR A 207 10.958 25.778 46.085 1.00 22.70 C ATOM 1588 CD1 TYR A 207 10.304 26.759 46.866 1.00 24.76 C ATOM 1589 CD2 TYR A 207 12.194 26.105 45.515 1.00 27.79 C ATOM 1590 CE1 TYR A 207 10.914 27.987 47.124 1.00 28.31 C ATOM 1591 CE2 TYR A 207 12.775 27.323 45.709 1.00 25.49 C ATOM 1592 CZ TYR A 207 12.150 28.281 46.498 1.00 28.24 C ATOM 1593 OH TYR A 207 12.786 29.477 46.665 1.00 29.56 O ATOM 1594 N VAL A 208 9.522 21.519 46.701 1.00 19.81 N ATOM 1595 CA VAL A 208 9.124 20.229 46.191 1.00 21.80 C ATOM 1596 C VAL A 208 7.735 19.842 46.832 1.00 19.21 C ATOM 1597 O VAL A 208 6.816 19.425 46.122 1.00 20.61 O ATOM 1598 CB VAL A 208 10.218 19.143 46.522 1.00 21.00 C ATOM 1599 CG1 VAL A 208 9.716 17.771 46.262 1.00 21.50 C ATOM 1600 CG2 VAL A 208 11.426 19.422 45.629 1.00 22.62 C ATOM 1601 N SER A 209 7.695 19.977 48.166 1.00 23.59 N ATOM 1602 CA SER A 209 6.447 19.674 48.886 1.00 25.55 C ATOM 1603 C SER A 209 5.261 20.557 48.439 1.00 22.80 C ATOM 1604 O SER A 209 4.202 20.064 48.086 1.00 23.23 O ATOM 1605 CB SER A 209 6.610 19.775 50.394 1.00 26.05 C ATOM 1606 OG SER A 209 5.269 19.703 50.971 1.00 30.56 O ATOM 1607 N ALA A 210 5.511 21.854 48.364 1.00 25.28 N ATOM 1608 CA ALA A 210 4.491 22.803 47.905 1.00 24.71 C ATOM 1609 C ALA A 210 4.028 22.657 46.493 1.00 23.48 C ATOM 1610 O ALA A 210 2.828 22.763 46.201 1.00 25.01 O ATOM 1611 CB ALA A 210 4.951 24.224 48.200 1.00 23.20 C ATOM 1612 N SER A 211 4.930 22.297 45.515 1.00 19.29 N ATOM 1613 CA SER A 211 4.439 22.070 44.199 1.00 19.91 C ATOM 1614 C SER A 211 3.667 20.783 43.972 1.00 17.42 C ATOM 1615 O SER A 211 2.768 20.669 43.117 1.00 21.81 O ATOM 1616 CB SER A 211 5.641 22.143 43.152 1.00 20.84 C ATOM 1617 OG SER A 211 6.090 23.517 42.995 1.00 23.43 O ATOM 1618 N ALA A 212 4.100 19.730 44.704 1.00 20.65 N ATOM 1619 CA ALA A 212 3.392 18.446 44.659 1.00 19.40 C ATOM 1620 C ALA A 212 1.911 18.642 45.210 1.00 17.49 C ATOM 1621 O ALA A 212 0.985 18.244 44.533 1.00 21.67 O ATOM 1622 CB ALA A 212 4.139 17.397 45.537 1.00 19.25 C ATOM 1623 N ARG A 213 1.816 19.339 46.312 1.00 22.14 N ATOM 1624 CA ARG A 213 0.469 19.722 46.850 1.00 23.46 C ATOM 1625 C ARG A 213 -0.262 20.652 45.944 1.00 25.94 C ATOM 1626 O ARG A 213 -1.418 20.393 45.576 1.00 26.63 O ATOM 1627 CB ARG A 213 0.590 20.328 48.193 1.00 21.86 C ATOM 1628 CG ARG A 213 0.968 19.322 49.198 1.00 25.14 C ATOM 1629 CD ARG A 213 1.214 19.892 50.483 1.00 26.67 C ATOM 1630 NE ARG A 213 1.378 18.786 51.430 1.00 27.39 N ATOM 1631 CZ ARG A 213 1.885 18.853 52.643 1.00 23.16 C ATOM 1632 NH1 ARG A 213 1.978 17.732 53.366 1.00 27.58 N ATOM 1633 NH2 ARG A 213 2.178 19.991 53.236 1.00 28.14 N ATOM 1634 N ALA A 214 0.440 21.711 45.495 1.00 26.95 N ATOM 1635 CA ALA A 214 -0.195 22.670 44.621 1.00 28.10 C ATOM 1636 C ALA A 214 -0.738 21.943 43.449 1.00 26.49 C ATOM 1637 O ALA A 214 -1.846 22.143 43.041 1.00 27.97 O ATOM 1638 CB ALA A 214 0.761 23.873 44.214 1.00 27.69 C ATOM 1639 N ILE A 215 0.041 21.013 42.868 1.00 28.11 N ATOM 1640 CA ILE A 215 -0.453 20.300 41.706 1.00 26.01 C ATOM 1641 C ILE A 215 -1.677 19.357 41.971 1.00 28.36 C ATOM 1642 O ILE A 215 -2.634 19.261 41.144 1.00 27.24 O ATOM 1643 CB ILE A 215 0.699 19.455 41.064 1.00 26.40 C ATOM 1644 CG1 ILE A 215 1.711 20.355 40.337 1.00 26.63 C ATOM 1645 CG2 ILE A 215 0.157 18.511 40.073 1.00 23.51 C ATOM 1646 CD1 ILE A 215 2.913 19.535 39.738 1.00 26.71 C ATOM 1647 N LEU A 216 -1.616 18.624 43.086 1.00 29.45 N ATOM 1648 CA LEU A 216 -2.722 17.668 43.333 1.00 31.87 C ATOM 1649 C LEU A 216 -3.993 18.353 43.824 1.00 31.85 C ATOM 1650 O LEU A 216 -5.095 17.933 43.461 1.00 32.07 O ATOM 1651 CB LEU A 216 -2.309 16.631 44.355 1.00 32.38 C ATOM 1652 CG LEU A 216 -1.725 15.334 43.807 1.00 32.28 C ATOM 1653 CD1 LEU A 216 -1.312 14.491 45.015 1.00 36.49 C ATOM 1654 CD2 LEU A 216 -2.714 14.562 42.867 1.00 35.75 C ATOM 1655 N GLU A 217 -3.794 19.346 44.688 1.00 31.39 N ATOM 1656 CA GLU A 217 -4.877 19.982 45.452 1.00 33.37 C ATOM 1657 C GLU A 217 -5.368 21.299 44.891 1.00 36.13 C ATOM 1658 O GLU A 217 -6.384 21.815 45.387 1.00 36.70 O ATOM 1659 CB GLU A 217 -4.438 20.216 46.884 1.00 32.95 C ATOM 1660 CG GLU A 217 -4.103 18.902 47.598 1.00 32.60 C ATOM 1661 CD GLU A 217 -3.538 19.102 48.961 1.00 32.90 C ATOM 1662 OE1 GLU A 217 -3.132 20.213 49.236 1.00 33.91 O ATOM 1663 OE2 GLU A 217 -3.515 18.155 49.814 1.00 37.56 O ATOM 1664 N GLU A 218 -4.661 21.881 43.908 1.00 36.61 N ATOM 1665 CA GLU A 218 -5.124 23.163 43.316 1.00 37.84 C ATOM 1666 C GLU A 218 -5.210 23.136 41.801 1.00 38.74 C ATOM 1667 O GLU A 218 -6.075 23.801 41.237 1.00 40.12 O ATOM 1668 CB GLU A 218 -4.304 24.382 43.763 1.00 37.51 C ATOM 1669 CG GLU A 218 -4.204 24.638 45.249 1.00 39.70 C ATOM 1670 CD GLU A 218 -3.309 25.857 45.591 1.00 46.18 C ATOM 1671 OE1 GLU A 218 -2.992 26.107 46.790 1.00 44.52 O ATOM 1672 OE2 GLU A 218 -2.914 26.584 44.653 1.00 49.31 O ATOM 1673 N GLN A 219 -4.373 22.338 41.134 1.00 38.74 N ATOM 1674 CA GLN A 219 -4.287 22.399 39.676 1.00 39.21 C ATOM 1675 C GLN A 219 -4.993 21.339 38.858 1.00 39.89 C ATOM 1676 O GLN A 219 -5.168 21.522 37.663 1.00 40.98 O ATOM 1677 CB GLN A 219 -2.818 22.585 39.210 1.00 38.88 C ATOM 1678 CG GLN A 219 -2.076 23.699 39.967 1.00 38.29 C ATOM 1679 CD GLN A 219 -2.721 25.071 39.780 1.00 39.41 C ATOM 1680 OE1 GLN A 219 -3.456 25.283 38.819 1.00 40.33 O ATOM 1681 NE2 GLN A 219 -2.400 26.018 40.670 1.00 37.77 N ATOM 1682 N GLY A 220 -5.444 20.236 39.457 1.00 40.82 N ATOM 1683 CA GLY A 220 -6.089 19.188 38.648 1.00 41.01 C ATOM 1684 C GLY A 220 -5.294 17.886 38.531 1.00 40.97 C ATOM 1685 O GLY A 220 -5.608 16.994 37.729 1.00 42.62 O ATOM 1686 N GLY A 221 -4.260 17.764 39.345 1.00 40.57 N ATOM 1687 CA GLY A 221 -3.476 16.546 39.381 1.00 38.50 C ATOM 1688 C GLY A 221 -2.520 16.375 38.232 1.00 36.43 C ATOM 1689 O GLY A 221 -2.108 17.339 37.557 1.00 35.97 O ATOM 1690 N LEU A 222 -2.170 15.127 38.004 1.00 34.32 N ATOM 1691 CA LEU A 222 -1.231 14.733 36.995 1.00 33.01 C ATOM 1692 C LEU A 222 -1.728 15.107 35.614 1.00 32.31 C ATOM 1693 O LEU A 222 -0.938 15.413 34.727 1.00 31.32 O ATOM 1694 CB LEU A 222 -1.012 13.202 37.104 1.00 32.01 C ATOM 1695 CG LEU A 222 -0.086 12.435 36.177 1.00 33.96 C ATOM 1696 CD1 LEU A 222 1.380 13.014 36.205 1.00 29.48 C ATOM 1697 CD2 LEU A 222 -0.124 10.969 36.536 1.00 35.84 C ATOM 1698 N ALA A 223 -3.042 15.087 35.413 1.00 31.40 N ATOM 1699 CA ALA A 223 -3.632 15.409 34.102 1.00 29.83 C ATOM 1700 C ALA A 223 -3.297 16.849 33.698 1.00 27.41 C ATOM 1701 O ALA A 223 -3.129 17.105 32.525 1.00 30.03 O ATOM 1702 CB ALA A 223 -5.168 15.284 34.179 1.00 30.82 C ATOM 1703 N TRP A 224 -3.297 17.774 34.660 1.00 26.79 N ATOM 1704 CA TRP A 224 -2.961 19.190 34.383 1.00 27.16 C ATOM 1705 C TRP A 224 -1.585 19.278 33.756 1.00 27.23 C ATOM 1706 O TRP A 224 -1.395 19.970 32.781 1.00 24.66 O ATOM 1707 CB TRP A 224 -3.003 20.045 35.632 1.00 28.51 C ATOM 1708 CG TRP A 224 -2.425 21.458 35.495 1.00 29.05 C ATOM 1709 CD1 TRP A 224 -3.029 22.554 34.924 1.00 31.03 C ATOM 1710 CD2 TRP A 224 -1.140 21.914 35.970 1.00 31.27 C ATOM 1711 NE1 TRP A 224 -2.202 23.672 35.038 1.00 31.46 N ATOM 1712 CE2 TRP A 224 -1.034 23.300 35.657 1.00 28.35 C ATOM 1713 CE3 TRP A 224 -0.069 21.293 36.619 1.00 28.59 C ATOM 1714 CZ2 TRP A 224 0.100 24.068 35.994 1.00 31.87 C ATOM 1715 CZ3 TRP A 224 1.053 22.057 36.943 1.00 30.31 C ATOM 1716 CH2 TRP A 224 1.125 23.439 36.630 1.00 33.68 C ATOM 1717 N LEU A 225 -0.640 18.549 34.309 1.00 27.08 N ATOM 1718 CA LEU A 225 0.740 18.611 33.776 1.00 26.73 C ATOM 1719 C LEU A 225 0.849 17.892 32.441 1.00 27.37 C ATOM 1720 O LEU A 225 1.409 18.410 31.485 1.00 28.28 O ATOM 1721 CB LEU A 225 1.696 17.986 34.776 1.00 26.76 C ATOM 1722 CG LEU A 225 3.178 18.072 34.477 1.00 25.69 C ATOM 1723 CD1 LEU A 225 3.673 19.571 34.182 1.00 24.80 C ATOM 1724 CD2 LEU A 225 3.890 17.599 35.697 1.00 25.22 C ATOM 1725 N GLN A 226 0.289 16.695 32.349 1.00 27.97 N ATOM 1726 CA GLN A 226 0.461 15.843 31.189 1.00 29.63 C ATOM 1727 C GLN A 226 -0.124 16.515 29.964 1.00 28.41 C ATOM 1728 O GLN A 226 0.438 16.390 28.896 1.00 28.84 O ATOM 1729 CB GLN A 226 -0.196 14.433 31.372 1.00 29.87 C ATOM 1730 CG GLN A 226 0.418 13.522 32.464 1.00 35.29 C ATOM 1731 CD GLN A 226 -0.227 12.083 32.503 1.00 40.66 C ATOM 1732 OE1 GLN A 226 0.485 11.073 32.588 1.00 46.19 O ATOM 1733 NE2 GLN A 226 -1.556 12.010 32.435 1.00 41.14 N ATOM 1734 N GLN A 227 -1.257 17.199 30.136 1.00 28.73 N ATOM 1735 CA GLN A 227 -1.969 17.853 29.000 1.00 29.13 C ATOM 1736 C GLN A 227 -1.239 19.104 28.448 1.00 28.55 C ATOM 1737 O GLN A 227 -1.523 19.571 27.356 1.00 27.71 O ATOM 1738 CB GLN A 227 -3.416 18.222 29.398 1.00 29.88 C ATOM 1739 CG GLN A 227 -3.468 19.062 30.710 1.00 37.12 C ATOM 1740 CD GLN A 227 -3.760 20.564 30.584 1.00 42.39 C ATOM 1741 OE1 GLN A 227 -3.372 21.377 31.474 1.00 37.16 O ATOM 1742 NE2 GLN A 227 -4.507 20.944 29.522 1.00 45.50 N ATOM 1743 N LEU A 228 -0.311 19.647 29.209 1.00 27.00 N ATOM 1744 CA LEU A 228 0.582 20.700 28.659 1.00 25.77 C ATOM 1745 C LEU A 228 1.412 20.236 27.451 1.00 25.08 C ATOM 1746 O LEU A 228 1.812 21.099 26.620 1.00 23.21 O ATOM 1747 CB LEU A 228 1.472 21.161 29.741 1.00 24.78 C ATOM 1748 CG LEU A 228 0.999 22.313 30.594 1.00 27.22 C ATOM 1749 CD1 LEU A 228 -0.467 22.857 30.417 1.00 27.00 C ATOM 1750 CD2 LEU A 228 1.546 22.519 32.041 1.00 22.93 C ATOM 1751 N ARG A 229 1.665 18.940 27.298 1.00 24.52 N ATOM 1752 CA ARG A 229 2.308 18.432 26.099 1.00 25.99 C ATOM 1753 C ARG A 229 1.591 18.890 24.811 1.00 26.45 C ATOM 1754 O ARG A 229 2.213 18.956 23.709 1.00 26.32 O ATOM 1755 CB ARG A 229 2.388 16.908 26.120 1.00 24.70 C ATOM 1756 CG ARG A 229 3.754 16.386 26.396 1.00 27.13 C ATOM 1757 CD ARG A 229 3.824 14.890 26.770 1.00 28.13 C ATOM 1758 NE ARG A 229 5.195 14.709 27.291 1.00 29.78 N ATOM 1759 CZ ARG A 229 5.745 13.550 27.661 1.00 35.93 C ATOM 1760 NH1 ARG A 229 5.017 12.417 27.595 1.00 32.49 N ATOM 1761 NH2 ARG A 229 7.036 13.523 28.117 1.00 25.86 N ATOM 1762 N GLU A 230 0.275 19.124 24.895 1.00 28.05 N ATOM 1763 CA GLU A 230 -0.510 19.378 23.651 1.00 27.91 C ATOM 1764 C GLU A 230 -0.842 20.849 23.616 1.00 28.06 C ATOM 1765 O GLU A 230 -1.210 21.359 22.567 1.00 28.50 O ATOM 1766 CB GLU A 230 -1.820 18.560 23.579 1.00 28.41 C ATOM 1767 CG GLU A 230 -1.626 17.103 23.190 1.00 32.77 C ATOM 1768 CD GLU A 230 -1.507 16.166 24.401 1.00 40.29 C ATOM 1769 OE1 GLU A 230 -0.603 15.284 24.407 1.00 43.57 O ATOM 1770 OE2 GLU A 230 -2.350 16.272 25.328 1.00 45.39 O ATOM 1771 N SER A 231 -0.746 21.529 24.753 1.00 27.13 N ATOM 1772 CA SER A 231 -0.761 23.002 24.757 1.00 27.14 C ATOM 1773 C SER A 231 0.445 23.701 24.082 1.00 28.14 C ATOM 1774 O SER A 231 1.508 23.101 23.873 1.00 26.79 O ATOM 1775 CB SER A 231 -0.853 23.540 26.141 1.00 26.99 C ATOM 1776 OG SER A 231 -1.930 22.945 26.848 1.00 27.40 O ATOM 1777 N SER A 232 0.232 24.967 23.680 1.00 27.89 N ATOM 1778 CA SER A 232 1.311 25.775 23.117 1.00 26.73 C ATOM 1779 C SER A 232 2.432 26.040 24.116 1.00 24.64 C ATOM 1780 O SER A 232 2.224 26.142 25.325 1.00 23.24 O ATOM 1781 CB SER A 232 0.725 27.124 22.624 1.00 25.65 C ATOM 1782 OG SER A 232 0.534 28.026 23.659 1.00 27.90 O ATOM 1783 N TYR A 233 3.657 26.250 23.601 1.00 24.33 N ATOM 1784 CA TYR A 233 4.723 26.714 24.475 1.00 24.31 C ATOM 1785 C TYR A 233 4.371 27.848 25.435 1.00 23.07 C ATOM 1786 O TYR A 233 4.655 27.891 26.639 1.00 22.17 O ATOM 1787 CB TYR A 233 5.891 27.128 23.559 1.00 22.94 C ATOM 1788 CG TYR A 233 7.051 27.829 24.244 1.00 21.22 C ATOM 1789 CD1 TYR A 233 7.567 27.399 25.493 1.00 23.11 C ATOM 1790 CD2 TYR A 233 7.737 28.908 23.561 1.00 20.26 C ATOM 1791 CE1 TYR A 233 8.656 28.011 26.085 1.00 19.54 C ATOM 1792 CE2 TYR A 233 8.817 29.526 24.122 1.00 19.75 C ATOM 1793 CZ TYR A 233 9.314 29.074 25.367 1.00 20.81 C ATOM 1794 OH TYR A 233 10.406 29.616 25.939 1.00 20.60 O ATOM 1795 N GLU A 234 3.765 28.885 24.845 1.00 25.26 N ATOM 1796 CA GLU A 234 3.379 30.033 25.578 1.00 26.64 C ATOM 1797 C GLU A 234 2.468 29.690 26.773 1.00 25.88 C ATOM 1798 O GLU A 234 2.695 30.161 27.877 1.00 25.56 O ATOM 1799 CB GLU A 234 2.713 30.997 24.558 1.00 28.56 C ATOM 1800 CG GLU A 234 3.759 31.577 23.571 1.00 31.56 C ATOM 1801 CD GLU A 234 4.198 30.704 22.348 1.00 37.41 C ATOM 1802 OE1 GLU A 234 3.625 29.626 21.981 1.00 32.16 O ATOM 1803 OE2 GLU A 234 5.177 31.171 21.700 1.00 39.84 O ATOM 1804 N GLU A 235 1.485 28.836 26.512 1.00 28.32 N ATOM 1805 CA GLU A 235 0.469 28.430 27.514 1.00 28.55 C ATOM 1806 C GLU A 235 1.134 27.508 28.566 1.00 27.26 C ATOM 1807 O GLU A 235 0.967 27.729 29.781 1.00 25.70 O ATOM 1808 CB GLU A 235 -0.648 27.636 26.843 1.00 29.05 C ATOM 1809 CG GLU A 235 -1.520 28.378 25.825 1.00 36.48 C ATOM 1810 CD GLU A 235 -2.600 29.165 26.511 1.00 47.23 C ATOM 1811 OE1 GLU A 235 -2.279 29.927 27.470 1.00 48.74 O ATOM 1812 OE2 GLU A 235 -3.776 29.001 26.089 1.00 52.93 O ATOM 1813 N ALA A 236 1.874 26.504 28.058 1.00 25.71 N ATOM 1814 CA ALA A 236 2.666 25.602 28.972 1.00 24.78 C ATOM 1815 C ALA A 236 3.615 26.356 29.925 1.00 24.71 C ATOM 1816 O ALA A 236 3.617 26.146 31.143 1.00 24.51 O ATOM 1817 CB ALA A 236 3.375 24.532 28.190 1.00 24.56 C ATOM 1818 N HIS A 237 4.426 27.308 29.398 1.00 22.19 N ATOM 1819 CA HIS A 237 5.334 28.064 30.224 1.00 23.19 C ATOM 1820 C HIS A 237 4.670 28.883 31.303 1.00 23.10 C ATOM 1821 O HIS A 237 5.090 28.916 32.446 1.00 23.46 O ATOM 1822 CB HIS A 237 6.224 28.964 29.307 1.00 21.03 C ATOM 1823 CG HIS A 237 7.358 29.630 30.015 1.00 23.10 C ATOM 1824 ND1 HIS A 237 7.220 30.767 30.783 1.00 24.57 N ATOM 1825 CD2 HIS A 237 8.676 29.283 30.095 1.00 20.90 C ATOM 1826 CE1 HIS A 237 8.399 31.101 31.293 1.00 22.97 C ATOM 1827 NE2 HIS A 237 9.287 30.181 30.926 1.00 20.66 N ATOM 1828 N LYS A 238 3.631 29.648 30.897 1.00 25.62 N ATOM 1829 CA LYS A 238 2.847 30.399 31.828 1.00 27.04 C ATOM 1830 C LYS A 238 2.190 29.463 32.907 1.00 26.62 C ATOM 1831 O LYS A 238 2.306 29.786 34.067 1.00 25.86 O ATOM 1832 CB LYS A 238 1.809 31.209 31.018 1.00 28.90 C ATOM 1833 CG LYS A 238 0.715 31.848 31.834 1.00 32.83 C ATOM 1834 CD LYS A 238 -0.515 32.038 30.923 1.00 41.50 C ATOM 1835 CE LYS A 238 -0.308 33.174 29.902 1.00 47.43 C ATOM 1836 NZ LYS A 238 -0.771 34.483 30.486 1.00 50.19 N ATOM 1837 N ALA A 239 1.651 28.319 32.485 1.00 26.22 N ATOM 1838 CA ALA A 239 0.980 27.344 33.448 1.00 26.06 C ATOM 1839 C ALA A 239 2.016 26.926 34.507 1.00 26.56 C ATOM 1840 O ALA A 239 1.817 27.037 35.729 1.00 27.08 O ATOM 1841 CB ALA A 239 0.412 26.144 32.708 1.00 25.39 C ATOM 1842 N LEU A 240 3.199 26.535 34.022 1.00 24.63 N ATOM 1843 CA LEU A 240 4.207 26.058 34.949 1.00 24.19 C ATOM 1844 C LEU A 240 4.727 27.102 35.926 1.00 24.58 C ATOM 1845 O LEU A 240 5.075 26.804 37.035 1.00 23.49 O ATOM 1846 CB LEU A 240 5.394 25.481 34.180 1.00 23.43 C ATOM 1847 CG LEU A 240 5.174 24.226 33.377 1.00 24.97 C ATOM 1848 CD1 LEU A 240 6.344 23.984 32.457 1.00 27.61 C ATOM 1849 CD2 LEU A 240 4.970 23.073 34.386 1.00 24.71 C ATOM 1850 N CYS A 241 4.782 28.388 35.537 1.00 24.36 N ATOM 1851 CA CYS A 241 5.326 29.372 36.487 1.00 25.97 C ATOM 1852 C CYS A 241 4.459 29.634 37.739 1.00 26.36 C ATOM 1853 O CYS A 241 4.923 30.325 38.651 1.00 26.91 O ATOM 1854 CB CYS A 241 5.545 30.733 35.803 1.00 26.86 C ATOM 1855 SG CYS A 241 7.018 30.723 34.678 1.00 30.49 S ATOM 1856 N ILE A 242 3.250 29.064 37.795 1.00 27.86 N ATOM 1857 CA ILE A 242 2.364 29.119 39.014 1.00 29.93 C ATOM 1858 C ILE A 242 3.028 28.442 40.241 1.00 28.18 C ATOM 1859 O ILE A 242 2.925 28.903 41.416 1.00 28.30 O ATOM 1860 CB ILE A 242 1.008 28.411 38.740 1.00 31.11 C ATOM 1861 CG1 ILE A 242 0.240 29.074 37.567 1.00 34.55 C ATOM 1862 CG2 ILE A 242 0.130 28.443 39.964 1.00 36.56 C ATOM 1863 CD1 ILE A 242 -0.826 28.103 36.849 1.00 35.49 C ATOM 1864 N LEU A 243 3.827 27.412 39.914 1.00 26.46 N ATOM 1865 CA LEU A 243 4.390 26.498 40.927 1.00 24.41 C ATOM 1866 C LEU A 243 5.544 27.035 41.713 1.00 24.93 C ATOM 1867 O LEU A 243 6.484 27.649 41.192 1.00 23.75 O ATOM 1868 CB LEU A 243 4.753 25.158 40.246 1.00 22.22 C ATOM 1869 CG LEU A 243 3.728 24.423 39.416 1.00 23.04 C ATOM 1870 CD1 LEU A 243 4.286 23.197 38.579 1.00 19.79 C ATOM 1871 CD2 LEU A 243 2.608 23.924 40.383 1.00 21.40 C ATOM 1872 N PRO A 244 5.580 26.769 42.986 1.00 23.16 N ATOM 1873 CA PRO A 244 6.641 27.086 43.911 1.00 22.30 C ATOM 1874 C PRO A 244 8.003 26.469 43.416 1.00 25.44 C ATOM 1875 O PRO A 244 8.074 25.271 43.160 1.00 25.95 O ATOM 1876 CB PRO A 244 6.170 26.406 45.213 1.00 26.12 C ATOM 1877 CG PRO A 244 4.737 26.407 45.067 1.00 23.27 C ATOM 1878 CD PRO A 244 4.405 26.156 43.669 1.00 24.65 C ATOM 1879 N GLY A 245 9.022 27.334 43.245 1.00 23.73 N ATOM 1880 CA GLY A 245 10.396 26.928 42.868 1.00 23.82 C ATOM 1881 C GLY A 245 10.539 26.994 41.364 1.00 22.37 C ATOM 1882 O GLY A 245 11.678 26.732 40.864 1.00 22.74 O ATOM 1883 N VAL A 246 9.436 27.153 40.637 1.00 21.60 N ATOM 1884 CA VAL A 246 9.441 27.248 39.184 1.00 19.78 C ATOM 1885 C VAL A 246 9.371 28.707 38.732 1.00 22.42 C ATOM 1886 O VAL A 246 8.329 29.323 38.833 1.00 22.84 O ATOM 1887 CB VAL A 246 8.336 26.440 38.458 1.00 21.60 C ATOM 1888 CG1 VAL A 246 8.453 26.544 36.936 1.00 20.52 C ATOM 1889 CG2 VAL A 246 8.317 24.959 38.903 1.00 19.49 C ATOM 1890 N GLY A 247 10.481 29.247 38.223 1.00 21.74 N ATOM 1891 CA GLY A 247 10.488 30.557 37.555 1.00 22.58 C ATOM 1892 C GLY A 247 10.670 30.357 36.079 1.00 20.45 C ATOM 1893 O GLY A 247 10.494 29.256 35.545 1.00 20.39 O ATOM 1894 N THR A 248 11.011 31.435 35.343 1.00 21.00 N ATOM 1895 CA THR A 248 11.079 31.330 33.903 1.00 20.91 C ATOM 1896 C THR A 248 12.082 30.310 33.342 1.00 16.98 C ATOM 1897 O THR A 248 11.780 29.605 32.389 1.00 17.53 O ATOM 1898 CB THR A 248 11.508 32.714 33.296 1.00 21.77 C ATOM 1899 OG1 THR A 248 10.617 33.717 33.816 1.00 28.80 O ATOM 1900 CG2 THR A 248 11.409 32.645 31.840 1.00 25.03 C ATOM 1901 N CYS A 249 13.216 30.247 33.999 1.00 18.05 N ATOM 1902 CA CYS A 249 14.264 29.342 33.460 1.00 15.27 C ATOM 1903 C CYS A 249 13.866 27.836 33.734 1.00 14.53 C ATOM 1904 O CYS A 249 13.947 26.974 32.819 1.00 15.63 O ATOM 1905 CB CYS A 249 15.546 29.640 34.159 1.00 13.78 C ATOM 1906 SG CYS A 249 17.010 28.719 33.527 1.00 16.39 S ATOM 1907 N VAL A 250 13.476 27.541 34.968 1.00 15.96 N ATOM 1908 CA VAL A 250 13.011 26.130 35.283 1.00 16.14 C ATOM 1909 C VAL A 250 11.860 25.740 34.417 1.00 15.45 C ATOM 1910 O VAL A 250 11.816 24.618 33.781 1.00 15.79 O ATOM 1911 CB VAL A 250 12.672 26.001 36.793 1.00 16.70 C ATOM 1912 CG1 VAL A 250 11.957 24.654 37.037 1.00 16.16 C ATOM 1913 CG2 VAL A 250 13.910 26.046 37.585 1.00 15.93 C ATOM 1914 N ALA A 251 10.917 26.687 34.228 1.00 15.25 N ATOM 1915 CA ALA A 251 9.803 26.393 33.307 1.00 15.20 C ATOM 1916 C ALA A 251 10.175 26.076 31.878 1.00 13.88 C ATOM 1917 O ALA A 251 9.680 25.184 31.179 1.00 15.57 O ATOM 1918 CB ALA A 251 8.769 27.581 33.347 1.00 15.54 C ATOM 1919 N ASP A 252 11.142 26.892 31.356 1.00 16.35 N ATOM 1920 CA ASP A 252 11.709 26.620 30.060 1.00 16.61 C ATOM 1921 C ASP A 252 12.380 25.218 29.942 1.00 11.82 C ATOM 1922 O ASP A 252 12.254 24.540 28.929 1.00 14.35 O ATOM 1923 CB ASP A 252 12.710 27.769 29.693 1.00 17.14 C ATOM 1924 CG ASP A 252 11.995 28.962 29.013 1.00 17.55 C ATOM 1925 OD1 ASP A 252 11.099 28.660 28.176 1.00 19.33 O ATOM 1926 OD2 ASP A 252 12.355 30.081 29.411 1.00 20.33 O ATOM 1927 N LYS A 253 13.142 24.864 30.975 1.00 14.11 N ATOM 1928 CA LYS A 253 13.749 23.511 30.996 1.00 14.38 C ATOM 1929 C LYS A 253 12.729 22.411 30.945 1.00 13.31 C ATOM 1930 O LYS A 253 12.915 21.470 30.189 1.00 12.74 O ATOM 1931 CB LYS A 253 14.669 23.366 32.251 1.00 13.90 C ATOM 1932 CG LYS A 253 15.916 24.299 32.301 1.00 14.04 C ATOM 1933 CD LYS A 253 16.657 24.009 33.560 1.00 15.79 C ATOM 1934 CE LYS A 253 17.475 25.268 33.984 1.00 15.87 C ATOM 1935 NZ LYS A 253 16.694 26.390 34.709 1.00 18.19 N ATOM 1936 N ILE A 254 11.623 22.583 31.690 1.00 14.18 N ATOM 1937 CA ILE A 254 10.556 21.565 31.595 1.00 15.57 C ATOM 1938 C ILE A 254 9.823 21.544 30.295 1.00 14.36 C ATOM 1939 O ILE A 254 9.583 20.490 29.670 1.00 14.98 O ATOM 1940 CB ILE A 254 9.581 21.801 32.728 1.00 12.78 C ATOM 1941 CG1 ILE A 254 10.275 21.638 34.038 1.00 14.96 C ATOM 1942 CG2 ILE A 254 8.409 20.769 32.682 1.00 19.06 C ATOM 1943 CD1 ILE A 254 9.553 22.291 35.238 1.00 16.25 C ATOM 1944 N CYS A 255 9.550 22.765 29.751 1.00 16.24 N ATOM 1945 CA CYS A 255 8.978 22.853 28.401 1.00 15.38 C ATOM 1946 C CYS A 255 9.771 22.139 27.339 1.00 14.33 C ATOM 1947 O CYS A 255 9.294 21.361 26.548 1.00 14.91 O ATOM 1948 CB CYS A 255 8.747 24.324 27.905 1.00 16.64 C ATOM 1949 SG CYS A 255 7.385 25.109 28.782 1.00 20.34 S ATOM 1950 N LEU A 256 11.114 22.423 27.329 1.00 13.07 N ATOM 1951 CA LEU A 256 11.998 21.846 26.369 1.00 14.00 C ATOM 1952 C LEU A 256 12.173 20.320 26.464 1.00 11.82 C ATOM 1953 O LEU A 256 12.216 19.608 25.476 1.00 14.84 O ATOM 1954 CB LEU A 256 13.383 22.579 26.545 1.00 12.35 C ATOM 1955 CG LEU A 256 14.431 22.034 25.629 1.00 14.19 C ATOM 1956 CD1 LEU A 256 14.097 22.267 24.152 1.00 13.59 C ATOM 1957 CD2 LEU A 256 15.708 22.818 26.025 1.00 14.57 C ATOM 1958 N MET A 257 12.317 19.892 27.733 1.00 14.77 N ATOM 1959 CA MET A 257 12.864 18.557 28.018 1.00 15.10 C ATOM 1960 C MET A 257 11.773 17.518 28.338 1.00 15.52 C ATOM 1961 O MET A 257 12.046 16.340 28.231 1.00 16.73 O ATOM 1962 CB MET A 257 13.931 18.691 29.099 1.00 12.39 C ATOM 1963 CG MET A 257 15.107 19.488 28.488 1.00 14.92 C ATOM 1964 SD MET A 257 16.635 19.406 29.431 1.00 14.53 S ATOM 1965 CE MET A 257 16.563 20.933 30.337 1.00 14.31 C ATOM 1966 N ALA A 258 10.574 17.995 28.679 1.00 17.41 N ATOM 1967 CA ALA A 258 9.491 17.028 28.914 1.00 18.32 C ATOM 1968 C ALA A 258 8.196 17.338 28.184 1.00 18.52 C ATOM 1969 O ALA A 258 7.343 16.428 28.030 1.00 19.38 O ATOM 1970 CB ALA A 258 9.207 16.932 30.392 1.00 16.68 C ATOM 1971 N LEU A 259 8.013 18.577 27.714 1.00 16.86 N ATOM 1972 CA LEU A 259 6.664 18.953 27.171 1.00 17.31 C ATOM 1973 C LEU A 259 6.704 19.298 25.696 1.00 18.42 C ATOM 1974 O LEU A 259 5.723 19.914 25.176 1.00 18.92 O ATOM 1975 CB LEU A 259 6.034 20.087 27.941 1.00 15.56 C ATOM 1976 CG LEU A 259 5.983 20.100 29.466 1.00 16.64 C ATOM 1977 CD1 LEU A 259 5.472 21.320 30.080 1.00 18.67 C ATOM 1978 CD2 LEU A 259 5.087 18.866 29.912 1.00 19.53 C ATOM 1979 N ASP A 260 7.714 18.815 24.982 1.00 18.25 N ATOM 1980 CA ASP A 260 7.824 18.813 23.534 1.00 18.82 C ATOM 1981 C ASP A 260 7.748 20.213 22.971 1.00 19.62 C ATOM 1982 O ASP A 260 7.049 20.448 21.974 1.00 21.43 O ATOM 1983 CB ASP A 260 6.730 17.911 22.853 1.00 18.59 C ATOM 1984 CG ASP A 260 6.843 16.424 23.310 1.00 21.86 C ATOM 1985 OD1 ASP A 260 7.978 15.937 23.506 1.00 19.98 O ATOM 1986 OD2 ASP A 260 5.776 15.779 23.483 1.00 26.75 O ATOM 1987 N LYS A 261 8.437 21.141 23.635 1.00 17.63 N ATOM 1988 CA LYS A 261 8.490 22.541 23.074 1.00 16.89 C ATOM 1989 C LYS A 261 9.948 22.783 22.611 1.00 15.81 C ATOM 1990 O LYS A 261 10.724 23.334 23.484 1.00 17.06 O ATOM 1991 CB LYS A 261 8.124 23.552 24.112 1.00 16.14 C ATOM 1992 CG LYS A 261 6.818 23.333 24.919 1.00 19.77 C ATOM 1993 CD LYS A 261 5.638 23.022 23.994 1.00 23.80 C ATOM 1994 CE LYS A 261 4.450 22.797 24.976 1.00 22.78 C ATOM 1995 NZ LYS A 261 3.638 21.684 24.504 1.00 21.84 N ATOM 1996 N PRO A 262 10.298 22.327 21.363 1.00 17.66 N ATOM 1997 CA PRO A 262 11.717 22.440 20.995 1.00 16.53 C ATOM 1998 C PRO A 262 12.263 23.911 20.962 1.00 17.08 C ATOM 1999 O PRO A 262 13.506 24.056 20.873 1.00 17.66 O ATOM 2000 CB PRO A 262 11.822 21.776 19.665 1.00 18.52 C ATOM 2001 CG PRO A 262 10.537 21.026 19.422 1.00 21.04 C ATOM 2002 CD PRO A 262 9.513 21.632 20.308 1.00 17.53 C ATOM 2003 N GLN A 263 11.377 24.898 20.984 1.00 17.73 N ATOM 2004 CA GLN A 263 11.840 26.271 20.815 1.00 17.03 C ATOM 2005 C GLN A 263 12.130 26.901 22.148 1.00 17.96 C ATOM 2006 O GLN A 263 12.611 28.026 22.207 1.00 17.84 O ATOM 2007 CB GLN A 263 10.792 27.073 19.999 1.00 17.08 C ATOM 2008 CG GLN A 263 9.550 27.464 20.846 1.00 20.20 C ATOM 2009 CD GLN A 263 8.359 26.467 20.634 1.00 27.28 C ATOM 2010 OE1 GLN A 263 7.207 26.905 20.396 1.00 29.83 O ATOM 2011 NE2 GLN A 263 8.615 25.162 20.669 1.00 19.71 N ATOM 2012 N ALA A 264 11.861 26.210 23.297 1.00 17.02 N ATOM 2013 CA ALA A 264 12.044 26.785 24.549 1.00 15.55 C ATOM 2014 C ALA A 264 13.560 26.907 24.854 1.00 14.28 C ATOM 2015 O ALA A 264 14.280 25.920 24.702 1.00 16.17 O ATOM 2016 CB ALA A 264 11.344 25.904 25.699 1.00 16.22 C ATOM 2017 N VAL A 265 13.983 28.112 25.310 1.00 14.87 N ATOM 2018 CA VAL A 265 15.404 28.305 25.608 1.00 14.79 C ATOM 2019 C VAL A 265 15.599 28.731 27.052 1.00 15.07 C ATOM 2020 O VAL A 265 15.338 29.862 27.423 1.00 15.69 O ATOM 2021 CB VAL A 265 16.044 29.349 24.564 1.00 15.10 C ATOM 2022 CG1 VAL A 265 17.497 29.548 24.928 1.00 15.47 C ATOM 2023 CG2 VAL A 265 15.908 28.911 23.127 1.00 14.88 C ATOM 2024 N PRO A 266 16.104 27.832 27.914 1.00 14.46 N ATOM 2025 CA PRO A 266 16.324 28.233 29.332 1.00 13.44 C ATOM 2026 C PRO A 266 17.506 29.217 29.370 1.00 14.56 C ATOM 2027 O PRO A 266 18.547 28.884 28.800 1.00 16.71 O ATOM 2028 CB PRO A 266 16.712 26.914 30.042 1.00 14.80 C ATOM 2029 CG PRO A 266 16.317 25.805 29.053 1.00 14.79 C ATOM 2030 CD PRO A 266 16.400 26.410 27.660 1.00 14.46 C ATOM 2031 N VAL A 267 17.272 30.365 29.985 1.00 14.41 N ATOM 2032 CA VAL A 267 18.267 31.416 30.059 1.00 14.90 C ATOM 2033 C VAL A 267 18.680 31.607 31.510 1.00 14.65 C ATOM 2034 O VAL A 267 17.880 32.043 32.377 1.00 15.80 O ATOM 2035 CB VAL A 267 17.758 32.737 29.412 1.00 16.15 C ATOM 2036 CG1 VAL A 267 18.753 33.888 29.784 1.00 15.75 C ATOM 2037 CG2 VAL A 267 17.654 32.497 27.957 1.00 18.64 C ATOM 2038 N ASN A 268 19.959 31.351 31.762 1.00 13.79 N ATOM 2039 CA ASN A 268 20.655 31.511 33.026 1.00 14.72 C ATOM 2040 C ASN A 268 22.104 31.969 32.784 1.00 15.87 C ATOM 2041 O ASN A 268 22.355 32.403 31.653 1.00 14.03 O ATOM 2042 CB ASN A 268 20.648 30.208 33.873 1.00 14.76 C ATOM 2043 CG ASN A 268 21.317 29.005 33.176 1.00 16.07 C ATOM 2044 OD1 ASN A 268 21.605 29.036 31.978 1.00 13.94 O ATOM 2045 ND2 ASN A 268 21.508 27.910 33.907 1.00 16.05 N ATOM 2046 N VAL A 269 22.946 31.982 33.815 1.00 16.79 N ATOM 2047 CA VAL A 269 24.231 32.677 33.661 1.00 15.83 C ATOM 2048 C VAL A 269 25.098 31.897 32.634 1.00 16.25 C ATOM 2049 O VAL A 269 25.778 32.556 31.843 1.00 16.75 O ATOM 2050 CB VAL A 269 24.947 32.869 34.961 1.00 17.21 C ATOM 2051 CG1 VAL A 269 26.455 33.077 34.793 1.00 20.34 C ATOM 2052 CG2 VAL A 269 24.328 34.032 35.716 1.00 17.66 C ATOM 2053 N HIS A 270 24.978 30.574 32.529 1.00 13.72 N ATOM 2054 CA HIS A 270 25.701 29.854 31.487 1.00 14.74 C ATOM 2055 C HIS A 270 25.355 30.449 30.098 1.00 14.71 C ATOM 2056 O HIS A 270 26.262 30.539 29.234 1.00 14.54 O ATOM 2057 CB HIS A 270 25.290 28.426 31.442 1.00 15.40 C ATOM 2058 CG HIS A 270 26.148 27.517 32.284 1.00 11.44 C ATOM 2059 ND1 HIS A 270 27.461 27.167 31.914 1.00 16.06 N ATOM 2060 CD2 HIS A 270 25.875 26.798 33.419 1.00 14.12 C ATOM 2061 CE1 HIS A 270 27.932 26.299 32.796 1.00 17.67 C ATOM 2062 NE2 HIS A 270 26.995 26.080 33.716 1.00 15.56 N ATOM 2063 N MET A 271 24.094 30.714 29.849 1.00 12.50 N ATOM 2064 CA MET A 271 23.664 31.200 28.521 1.00 13.75 C ATOM 2065 C MET A 271 24.080 32.647 28.282 1.00 15.16 C ATOM 2066 O MET A 271 24.350 33.048 27.107 1.00 16.35 O ATOM 2067 CB MET A 271 22.153 30.995 28.326 1.00 14.12 C ATOM 2068 CG MET A 271 21.760 29.450 28.315 1.00 15.03 C ATOM 2069 SD MET A 271 22.744 28.351 27.407 1.00 14.64 S ATOM 2070 CE MET A 271 22.643 29.023 25.699 1.00 15.79 C ATOM 2071 N TRP A 272 24.184 33.410 29.348 1.00 14.54 N ATOM 2072 CA TRP A 272 24.684 34.810 29.242 1.00 15.63 C ATOM 2073 C TRP A 272 26.146 34.738 28.872 1.00 16.22 C ATOM 2074 O TRP A 272 26.603 35.526 27.978 1.00 16.50 O ATOM 2075 CB TRP A 272 24.527 35.587 30.584 1.00 18.00 C ATOM 2076 CG TRP A 272 23.249 36.225 30.650 1.00 19.88 C ATOM 2077 CD1 TRP A 272 22.006 35.665 30.947 1.00 20.41 C ATOM 2078 CD2 TRP A 272 23.026 37.613 30.469 1.00 17.60 C ATOM 2079 NE1 TRP A 272 21.017 36.649 30.955 1.00 17.92 N ATOM 2080 CE2 TRP A 272 21.632 37.848 30.622 1.00 19.07 C ATOM 2081 CE3 TRP A 272 23.888 38.705 30.165 1.00 19.70 C ATOM 2082 CZ2 TRP A 272 21.086 39.104 30.494 1.00 22.15 C ATOM 2083 CZ3 TRP A 272 23.315 39.953 30.052 1.00 19.27 C ATOM 2084 CH2 TRP A 272 21.952 40.153 30.210 1.00 19.52 C ATOM 2085 N HIS A 273 26.887 33.834 29.512 1.00 15.61 N ATOM 2086 CA HIS A 273 28.326 33.710 29.210 1.00 16.21 C ATOM 2087 C HIS A 273 28.513 33.360 27.731 1.00 16.75 C ATOM 2088 O HIS A 273 29.349 34.001 27.019 1.00 16.84 O ATOM 2089 CB HIS A 273 29.033 32.719 30.097 1.00 17.65 C ATOM 2090 CG HIS A 273 29.245 33.232 31.488 1.00 22.23 C ATOM 2091 ND1 HIS A 273 29.625 32.396 32.520 1.00 26.22 N ATOM 2092 CD2 HIS A 273 29.082 34.464 32.032 1.00 26.20 C ATOM 2093 CE1 HIS A 273 29.725 33.109 33.635 1.00 21.58 C ATOM 2094 NE2 HIS A 273 29.387 34.357 33.374 1.00 30.14 N ATOM 2095 N ILE A 274 27.786 32.367 27.244 1.00 15.40 N ATOM 2096 CA ILE A 274 27.841 32.040 25.836 1.00 13.79 C ATOM 2097 C ILE A 274 27.449 33.227 24.931 1.00 14.10 C ATOM 2098 O ILE A 274 28.153 33.525 23.963 1.00 14.92 O ATOM 2099 CB ILE A 274 26.919 30.831 25.563 1.00 14.55 C ATOM 2100 CG1 ILE A 274 27.542 29.581 26.169 1.00 14.48 C ATOM 2101 CG2 ILE A 274 26.646 30.630 24.025 1.00 14.71 C ATOM 2102 CD1 ILE A 274 26.490 28.444 26.304 1.00 15.43 C ATOM 2103 N ALA A 275 26.313 33.852 25.207 1.00 14.04 N ATOM 2104 CA ALA A 275 25.834 34.967 24.439 1.00 12.77 C ATOM 2105 C ALA A 275 26.942 36.055 24.371 1.00 15.67 C ATOM 2106 O ALA A 275 27.184 36.622 23.284 1.00 15.37 O ATOM 2107 CB ALA A 275 24.560 35.554 25.055 1.00 14.56 C ATOM 2108 N GLN A 276 27.521 36.446 25.513 1.00 14.39 N ATOM 2109 CA GLN A 276 28.519 37.564 25.475 1.00 16.02 C ATOM 2110 C GLN A 276 29.839 37.147 24.876 1.00 15.65 C ATOM 2111 O GLN A 276 30.427 37.924 23.986 1.00 16.18 O ATOM 2112 CB GLN A 276 28.734 38.020 26.903 1.00 16.87 C ATOM 2113 CG GLN A 276 27.470 38.679 27.452 1.00 18.32 C ATOM 2114 CD GLN A 276 27.637 39.116 28.922 1.00 23.78 C ATOM 2115 OE1 GLN A 276 27.134 40.138 29.292 1.00 30.77 O ATOM 2116 NE2 GLN A 276 28.279 38.285 29.748 1.00 25.97 N ATOM 2117 N ARG A 277 30.321 35.965 25.210 1.00 15.90 N ATOM 2118 CA ARG A 277 31.609 35.535 24.724 1.00 15.75 C ATOM 2119 C ARG A 277 31.547 35.238 23.214 1.00 16.44 C ATOM 2120 O ARG A 277 32.458 35.619 22.442 1.00 18.09 O ATOM 2121 CB ARG A 277 32.126 34.319 25.533 1.00 17.90 C ATOM 2122 CG ARG A 277 33.476 33.824 25.072 1.00 23.93 C ATOM 2123 CD ARG A 277 33.898 32.525 25.839 1.00 30.08 C ATOM 2124 NE ARG A 277 33.174 31.370 25.314 1.00 37.40 N ATOM 2125 CZ ARG A 277 32.225 30.662 25.948 1.00 35.80 C ATOM 2126 NH1 ARG A 277 31.675 29.683 25.306 1.00 36.88 N ATOM 2127 NH2 ARG A 277 31.843 30.904 27.214 1.00 42.88 N ATOM 2128 N ASP A 278 30.513 34.552 22.747 1.00 13.34 N ATOM 2129 CA ASP A 278 30.602 33.981 21.399 1.00 12.80 C ATOM 2130 C ASP A 278 29.724 34.715 20.401 1.00 13.68 C ATOM 2131 O ASP A 278 29.844 34.403 19.193 1.00 15.46 O ATOM 2132 CB ASP A 278 30.159 32.482 21.483 1.00 15.38 C ATOM 2133 CG ASP A 278 31.070 31.699 22.441 1.00 19.04 C ATOM 2134 OD1 ASP A 278 30.578 30.866 23.248 1.00 21.94 O ATOM 2135 OD2 ASP A 278 32.299 31.892 22.345 1.00 21.77 O ATOM 2136 N TYR A 279 28.914 35.679 20.858 1.00 12.56 N ATOM 2137 CA TYR A 279 28.022 36.474 19.952 1.00 14.27 C ATOM 2138 C TYR A 279 28.107 37.972 20.189 1.00 14.84 C ATOM 2139 O TYR A 279 27.421 38.742 19.509 1.00 15.87 O ATOM 2140 CB TYR A 279 26.560 35.991 19.982 1.00 14.52 C ATOM 2141 CG TYR A 279 26.446 34.541 19.602 1.00 14.17 C ATOM 2142 CD1 TYR A 279 26.587 33.571 20.620 1.00 14.58 C ATOM 2143 CD2 TYR A 279 26.140 34.086 18.315 1.00 15.00 C ATOM 2144 CE1 TYR A 279 26.443 32.221 20.297 1.00 13.91 C ATOM 2145 CE2 TYR A 279 26.072 32.738 18.026 1.00 12.29 C ATOM 2146 CZ TYR A 279 26.220 31.818 19.013 1.00 13.95 C ATOM 2147 OH TYR A 279 26.088 30.506 18.697 1.00 13.11 O ATOM 2148 N SER A 280 28.874 38.373 21.212 1.00 13.82 N ATOM 2149 CA SER A 280 28.988 39.776 21.622 1.00 15.34 C ATOM 2150 C SER A 280 27.610 40.380 21.846 1.00 17.63 C ATOM 2151 O SER A 280 27.321 41.579 21.593 1.00 16.71 O ATOM 2152 CB SER A 280 29.804 40.567 20.549 1.00 15.39 C ATOM 2153 OG SER A 280 31.048 39.997 20.394 1.00 14.53 O ATOM 2154 N TRP A 281 26.661 39.550 22.358 1.00 16.35 N ATOM 2155 CA TRP A 281 25.321 40.023 22.598 1.00 15.32 C ATOM 2156 C TRP A 281 25.203 40.979 23.799 1.00 15.66 C ATOM 2157 O TRP A 281 25.921 40.830 24.828 1.00 17.98 O ATOM 2158 CB TRP A 281 24.456 38.758 22.908 1.00 14.25 C ATOM 2159 CG TRP A 281 22.994 39.105 23.054 1.00 16.41 C ATOM 2160 CD1 TRP A 281 22.090 39.234 22.068 1.00 16.09 C ATOM 2161 CD2 TRP A 281 22.286 39.345 24.285 1.00 14.12 C ATOM 2162 NE1 TRP A 281 20.884 39.584 22.580 1.00 17.96 N ATOM 2163 CE2 TRP A 281 20.983 39.636 23.947 1.00 15.43 C ATOM 2164 CE3 TRP A 281 22.662 39.348 25.640 1.00 15.52 C ATOM 2165 CZ2 TRP A 281 20.013 39.943 24.934 1.00 16.99 C ATOM 2166 CZ3 TRP A 281 21.712 39.603 26.621 1.00 16.44 C ATOM 2167 CH2 TRP A 281 20.408 39.899 26.253 1.00 16.28 C ATOM 2168 N HIS A 282 24.277 41.915 23.625 1.00 17.05 N ATOM 2169 CA HIS A 282 23.828 42.760 24.730 1.00 19.20 C ATOM 2170 C HIS A 282 22.384 43.030 24.551 1.00 18.96 C ATOM 2171 O HIS A 282 21.883 43.029 23.435 1.00 20.53 O ATOM 2172 CB AHIS A 282 24.467 44.153 24.638 0.50 19.81 C ATOM 2173 CG AHIS A 282 25.930 44.117 24.443 0.50 22.82 C ATOM 2174 ND1AHIS A 282 26.824 44.334 25.466 0.50 28.67 N ATOM 2175 CD2AHIS A 282 26.667 43.871 23.333 0.50 24.85 C ATOM 2176 CE1AHIS A 282 28.053 44.225 24.991 0.50 26.24 C ATOM 2177 NE2AHIS A 282 27.983 43.920 23.706 0.50 23.78 N ATOM 2178 CB BHIS A 282 24.743 44.000 24.883 0.50 19.07 C ATOM 2179 CG BHIS A 282 24.554 45.018 23.811 0.50 21.41 C ATOM 2180 ND1BHIS A 282 24.226 46.335 24.077 0.50 26.43 N ATOM 2181 CD2BHIS A 282 24.708 44.931 22.473 0.50 20.45 C ATOM 2182 CE1BHIS A 282 24.164 47.005 22.936 0.50 22.10 C ATOM 2183 NE2BHIS A 282 24.437 46.170 21.949 0.50 22.88 N ATOM 2184 N PRO A 283 21.663 43.321 25.674 1.00 20.12 N ATOM 2185 CA PRO A 283 20.246 43.670 25.573 1.00 23.48 C ATOM 2186 C PRO A 283 20.048 45.003 24.809 1.00 26.48 C ATOM 2187 O PRO A 283 20.917 45.898 24.972 1.00 26.97 O ATOM 2188 CB PRO A 283 19.783 43.788 27.041 1.00 22.41 C ATOM 2189 CG PRO A 283 20.883 43.395 27.821 1.00 20.45 C ATOM 2190 CD PRO A 283 22.165 43.279 27.051 1.00 19.36 C ATOM 2191 N THR A 284 19.010 45.041 23.982 1.00 30.50 N ATOM 2192 CA THR A 284 18.552 46.217 23.178 1.00 34.92 C ATOM 2193 C THR A 284 17.329 46.868 23.823 1.00 37.33 C ATOM 2194 O THR A 284 17.193 48.096 23.786 1.00 38.51 O ATOM 2195 CB THR A 284 17.944 45.832 21.757 1.00 34.87 C ATOM 2196 OG1 THR A 284 18.728 44.877 21.069 1.00 38.02 O ATOM 2197 CG2 THR A 284 17.749 47.056 20.843 1.00 39.24 C ATOM 2198 N THR A 285 16.389 46.054 24.313 1.00 38.90 N ATOM 2199 CA THR A 285 15.033 46.548 24.540 1.00 41.35 C ATOM 2200 C THR A 285 14.837 46.743 26.028 1.00 42.74 C ATOM 2201 O THR A 285 13.766 47.119 26.488 1.00 43.67 O ATOM 2202 CB THR A 285 13.901 45.697 23.823 1.00 41.92 C ATOM 2203 OG1 THR A 285 13.923 44.330 24.262 1.00 40.03 O ATOM 2204 CG2 THR A 285 14.074 45.723 22.312 1.00 43.30 C ATOM 2205 N SER A 286 15.918 46.532 26.765 1.00 43.64 N ATOM 2206 CA SER A 286 15.994 46.921 28.162 1.00 45.11 C ATOM 2207 C SER A 286 17.237 47.769 28.454 1.00 45.74 C ATOM 2208 O SER A 286 18.279 47.679 27.767 1.00 46.20 O ATOM 2209 CB SER A 286 15.992 45.678 29.055 1.00 45.20 C ATOM 2210 OG SER A 286 16.509 45.980 30.343 1.00 47.31 O ATOM 2211 N GLN A 287 17.102 48.560 29.511 1.00 46.45 N ATOM 2212 CA GLN A 287 18.152 49.394 30.093 1.00 46.99 C ATOM 2213 C GLN A 287 19.212 48.563 30.857 1.00 45.91 C ATOM 2214 O GLN A 287 20.411 48.933 30.879 1.00 45.74 O ATOM 2215 CB GLN A 287 17.528 50.412 31.085 1.00 48.15 C ATOM 2216 CG GLN A 287 15.956 50.485 31.142 1.00 52.69 C ATOM 2217 CD GLN A 287 15.266 49.192 31.647 1.00 55.36 C ATOM 2218 OE1 GLN A 287 14.601 48.494 30.875 1.00 58.39 O ATOM 2219 NE2 GLN A 287 15.407 48.894 32.931 1.00 55.98 N ATOM 2220 N ALA A 288 18.762 47.459 31.485 1.00 44.03 N ATOM 2221 CA ALA A 288 19.626 46.611 32.335 1.00 41.14 C ATOM 2222 C ALA A 288 20.794 45.998 31.555 1.00 39.87 C ATOM 2223 O ALA A 288 20.666 45.624 30.394 1.00 38.33 O ATOM 2224 CB ALA A 288 18.817 45.519 33.061 1.00 40.89 C ATOM 2225 N LYS A 289 21.939 45.913 32.211 1.00 38.95 N ATOM 2226 CA LYS A 289 23.148 45.417 31.564 1.00 37.88 C ATOM 2227 C LYS A 289 23.367 43.945 31.826 1.00 36.66 C ATOM 2228 O LYS A 289 24.244 43.310 31.229 1.00 36.01 O ATOM 2229 CB LYS A 289 24.356 46.153 32.116 1.00 39.06 C ATOM 2230 CG LYS A 289 24.277 47.638 31.951 1.00 41.41 C ATOM 2231 CD LYS A 289 24.663 48.057 30.573 1.00 41.39 C ATOM 2232 CE LYS A 289 24.885 49.566 30.537 1.00 43.50 C ATOM 2233 NZ LYS A 289 25.389 49.939 29.183 1.00 42.38 N ATOM 2234 N GLY A 290 22.600 43.423 32.774 1.00 34.24 N ATOM 2235 CA GLY A 290 22.804 42.081 33.259 1.00 31.15 C ATOM 2236 C GLY A 290 21.492 41.361 33.372 1.00 30.55 C ATOM 2237 O GLY A 290 20.424 41.912 32.997 1.00 30.73 O ATOM 2238 N PRO A 291 21.565 40.107 33.851 1.00 29.71 N ATOM 2239 CA PRO A 291 20.372 39.283 33.930 1.00 29.48 C ATOM 2240 C PRO A 291 19.295 39.962 34.800 1.00 28.24 C ATOM 2241 O PRO A 291 19.616 40.459 35.879 1.00 29.40 O ATOM 2242 CB PRO A 291 20.862 37.958 34.550 1.00 29.20 C ATOM 2243 CG PRO A 291 22.395 37.934 34.406 1.00 30.23 C ATOM 2244 CD PRO A 291 22.822 39.400 34.204 1.00 28.76 C ATOM 2245 N SER A 292 18.062 39.968 34.278 1.00 26.75 N ATOM 2246 CA SER A 292 16.887 40.529 34.872 1.00 26.65 C ATOM 2247 C SER A 292 15.722 39.817 34.161 1.00 26.77 C ATOM 2248 O SER A 292 15.950 39.128 33.143 1.00 25.56 O ATOM 2249 CB SER A 292 16.917 42.057 34.586 1.00 25.25 C ATOM 2250 OG SER A 292 16.419 42.310 33.269 1.00 25.12 O ATOM 2251 N PRO A 293 14.463 39.955 34.626 1.00 26.01 N ATOM 2252 CA PRO A 293 13.414 39.277 33.868 1.00 26.94 C ATOM 2253 C PRO A 293 13.278 39.739 32.429 1.00 26.28 C ATOM 2254 O PRO A 293 13.085 38.925 31.539 1.00 27.21 O ATOM 2255 CB PRO A 293 12.127 39.557 34.692 1.00 27.54 C ATOM 2256 CG PRO A 293 12.719 39.642 36.116 1.00 27.00 C ATOM 2257 CD PRO A 293 14.031 40.308 35.989 1.00 28.02 C ATOM 2258 N GLN A 294 13.400 41.042 32.198 1.00 27.35 N ATOM 2259 CA GLN A 294 13.324 41.570 30.845 1.00 26.79 C ATOM 2260 C GLN A 294 14.526 41.130 29.973 1.00 23.70 C ATOM 2261 O GLN A 294 14.332 40.730 28.856 1.00 23.38 O ATOM 2262 CB GLN A 294 13.378 43.084 30.914 1.00 29.12 C ATOM 2263 CG GLN A 294 12.125 43.848 31.156 1.00 36.41 C ATOM 2264 CD GLN A 294 12.397 45.308 30.791 1.00 46.23 C ATOM 2265 OE1 GLN A 294 13.172 46.010 31.484 1.00 50.04 O ATOM 2266 NE2 GLN A 294 11.860 45.740 29.646 1.00 47.73 N ATOM 2267 N THR A 295 15.752 41.189 30.501 1.00 22.63 N ATOM 2268 CA THR A 295 16.939 40.900 29.667 1.00 21.44 C ATOM 2269 C THR A 295 17.001 39.388 29.379 1.00 20.12 C ATOM 2270 O THR A 295 17.368 38.940 28.257 1.00 18.89 O ATOM 2271 CB THR A 295 18.276 41.432 30.273 1.00 21.99 C ATOM 2272 OG1 THR A 295 18.485 40.922 31.590 1.00 21.64 O ATOM 2273 CG2 THR A 295 18.313 43.042 30.311 1.00 21.48 C ATOM 2274 N ASN A 296 16.656 38.587 30.372 1.00 19.88 N ATOM 2275 CA ASN A 296 16.596 37.126 30.120 1.00 20.16 C ATOM 2276 C ASN A 296 15.604 36.764 29.064 1.00 20.16 C ATOM 2277 O ASN A 296 15.858 35.868 28.223 1.00 18.71 O ATOM 2278 CB ASN A 296 16.237 36.398 31.415 1.00 19.56 C ATOM 2279 CG ASN A 296 17.326 36.528 32.468 1.00 20.51 C ATOM 2280 OD1 ASN A 296 18.494 36.820 32.207 1.00 23.20 O ATOM 2281 ND2 ASN A 296 16.954 36.249 33.707 1.00 21.40 N ATOM 2282 N LYS A 297 14.445 37.464 29.091 1.00 21.77 N ATOM 2283 CA LYS A 297 13.410 37.219 28.084 1.00 21.32 C ATOM 2284 C LYS A 297 13.938 37.617 26.691 1.00 22.93 C ATOM 2285 O LYS A 297 13.781 36.867 25.720 1.00 21.69 O ATOM 2286 CB LYS A 297 12.070 37.921 28.435 1.00 23.82 C ATOM 2287 CG LYS A 297 11.040 37.745 27.362 1.00 24.44 C ATOM 2288 CD LYS A 297 9.758 38.528 27.756 1.00 28.90 C ATOM 2289 CE LYS A 297 8.534 37.958 26.977 1.00 34.02 C ATOM 2290 NZ LYS A 297 7.892 36.697 27.590 1.00 42.20 N ATOM 2291 N GLU A 298 14.610 38.772 26.637 1.00 21.19 N ATOM 2292 CA GLU A 298 15.189 39.214 25.350 1.00 21.97 C ATOM 2293 C GLU A 298 16.221 38.183 24.843 1.00 19.71 C ATOM 2294 O GLU A 298 16.290 37.836 23.656 1.00 19.92 O ATOM 2295 CB GLU A 298 15.836 40.620 25.507 1.00 22.41 C ATOM 2296 CG GLU A 298 16.452 41.075 24.206 1.00 24.98 C ATOM 2297 CD GLU A 298 16.954 42.514 24.245 1.00 32.02 C ATOM 2298 OE1 GLU A 298 17.636 42.853 23.248 1.00 34.11 O ATOM 2299 OE2 GLU A 298 16.736 43.223 25.279 1.00 28.79 O ATOM 2300 N LEU A 299 17.013 37.639 25.762 1.00 18.49 N ATOM 2301 CA LEU A 299 18.072 36.700 25.330 1.00 16.76 C ATOM 2302 C LEU A 299 17.459 35.418 24.778 1.00 16.17 C ATOM 2303 O LEU A 299 17.916 34.844 23.804 1.00 16.16 O ATOM 2304 CB LEU A 299 19.042 36.383 26.484 1.00 16.38 C ATOM 2305 CG LEU A 299 20.218 35.438 26.129 1.00 14.53 C ATOM 2306 CD1 LEU A 299 20.914 35.946 24.800 1.00 15.81 C ATOM 2307 CD2 LEU A 299 21.294 35.393 27.280 1.00 15.49 C ATOM 2308 N GLY A 300 16.424 34.899 25.475 1.00 16.16 N ATOM 2309 CA GLY A 300 15.765 33.735 24.905 1.00 14.65 C ATOM 2310 C GLY A 300 15.208 33.968 23.488 1.00 15.58 C ATOM 2311 O GLY A 300 15.315 33.180 22.558 1.00 16.26 O ATOM 2312 N ASN A 301 14.600 35.155 23.287 1.00 17.72 N ATOM 2313 CA ASN A 301 14.158 35.498 21.951 1.00 18.28 C ATOM 2314 C ASN A 301 15.283 35.645 20.914 1.00 14.83 C ATOM 2315 O ASN A 301 15.110 35.220 19.786 1.00 19.02 O ATOM 2316 CB ASN A 301 13.439 36.848 21.961 1.00 19.92 C ATOM 2317 CG ASN A 301 12.089 36.816 22.652 1.00 23.75 C ATOM 2318 OD1 ASN A 301 11.460 35.759 22.805 1.00 23.73 O ATOM 2319 ND2 ASN A 301 11.654 37.990 23.082 1.00 26.74 N ATOM 2320 N PHE A 302 16.443 36.151 21.338 1.00 16.25 N ATOM 2321 CA PHE A 302 17.602 36.224 20.470 1.00 16.23 C ATOM 2322 C PHE A 302 18.010 34.835 20.020 1.00 17.18 C ATOM 2323 O PHE A 302 18.237 34.609 18.853 1.00 16.72 O ATOM 2324 CB PHE A 302 18.779 36.927 21.203 1.00 16.74 C ATOM 2325 CG PHE A 302 20.066 36.766 20.492 1.00 15.66 C ATOM 2326 CD1 PHE A 302 20.339 37.630 19.423 1.00 20.06 C ATOM 2327 CD2 PHE A 302 21.019 35.796 20.863 1.00 16.88 C ATOM 2328 CE1 PHE A 302 21.496 37.509 18.726 1.00 19.31 C ATOM 2329 CE2 PHE A 302 22.252 35.679 20.143 1.00 19.77 C ATOM 2330 CZ PHE A 302 22.506 36.582 19.076 1.00 18.42 C ATOM 2331 N PHE A 303 18.092 33.840 20.961 1.00 15.27 N ATOM 2332 CA PHE A 303 18.428 32.475 20.496 1.00 15.57 C ATOM 2333 C PHE A 303 17.382 31.842 19.571 1.00 13.55 C ATOM 2334 O PHE A 303 17.751 31.125 18.688 1.00 13.93 O ATOM 2335 CB PHE A 303 18.736 31.552 21.693 1.00 14.41 C ATOM 2336 CG PHE A 303 20.070 31.871 22.379 1.00 16.50 C ATOM 2337 CD1 PHE A 303 20.142 32.260 23.699 1.00 16.76 C ATOM 2338 CD2 PHE A 303 21.246 31.810 21.655 1.00 16.05 C ATOM 2339 CE1 PHE A 303 21.371 32.507 24.329 1.00 15.56 C ATOM 2340 CE2 PHE A 303 22.516 32.124 22.268 1.00 16.84 C ATOM 2341 CZ PHE A 303 22.548 32.424 23.626 1.00 15.59 C ATOM 2342 N ARG A 304 16.069 32.138 19.771 1.00 15.53 N ATOM 2343 CA ARG A 304 15.087 31.609 18.828 1.00 18.21 C ATOM 2344 C ARG A 304 15.242 32.240 17.443 1.00 18.79 C ATOM 2345 O ARG A 304 15.066 31.553 16.456 1.00 18.80 O ATOM 2346 CB ARG A 304 13.637 31.774 19.331 1.00 19.03 C ATOM 2347 CG ARG A 304 13.181 30.632 20.335 1.00 19.07 C ATOM 2348 CD ARG A 304 11.709 30.836 20.678 1.00 18.91 C ATOM 2349 NE ARG A 304 11.598 31.895 21.632 1.00 17.99 N ATOM 2350 CZ ARG A 304 12.001 31.880 22.911 1.00 18.12 C ATOM 2351 NH1 ARG A 304 12.444 30.717 23.448 1.00 18.18 N ATOM 2352 NH2 ARG A 304 11.874 32.943 23.691 1.00 19.57 N ATOM 2353 N SER A 305 15.538 33.551 17.451 1.00 18.54 N ATOM 2354 CA SER A 305 15.664 34.258 16.161 1.00 22.15 C ATOM 2355 C SER A 305 16.897 33.700 15.418 1.00 20.97 C ATOM 2356 O SER A 305 16.887 33.561 14.170 1.00 23.41 O ATOM 2357 CB SER A 305 15.741 35.757 16.402 1.00 22.82 C ATOM 2358 OG SER A 305 16.981 36.073 17.000 1.00 31.48 O ATOM 2359 N LEU A 306 17.943 33.303 16.152 1.00 18.34 N ATOM 2360 CA LEU A 306 19.179 32.800 15.578 1.00 18.63 C ATOM 2361 C LEU A 306 18.997 31.381 15.038 1.00 18.66 C ATOM 2362 O LEU A 306 19.377 31.075 13.894 1.00 20.07 O ATOM 2363 CB LEU A 306 20.287 32.807 16.629 1.00 18.28 C ATOM 2364 CG LEU A 306 21.652 32.277 16.302 1.00 22.88 C ATOM 2365 CD1 LEU A 306 22.324 33.196 15.263 1.00 29.23 C ATOM 2366 CD2 LEU A 306 22.456 32.245 17.579 1.00 26.99 C ATOM 2367 N TRP A 307 18.402 30.509 15.869 1.00 16.92 N ATOM 2368 CA TRP A 307 18.377 29.100 15.519 1.00 17.78 C ATOM 2369 C TRP A 307 17.073 28.502 14.978 1.00 16.89 C ATOM 2370 O TRP A 307 17.135 27.450 14.375 1.00 18.97 O ATOM 2371 CB TRP A 307 18.855 28.275 16.757 1.00 18.20 C ATOM 2372 CG TRP A 307 20.259 28.510 17.156 1.00 15.13 C ATOM 2373 CD1 TRP A 307 21.355 28.675 16.328 1.00 15.90 C ATOM 2374 CD2 TRP A 307 20.763 28.572 18.504 1.00 15.49 C ATOM 2375 NE1 TRP A 307 22.498 28.814 17.074 1.00 15.94 N ATOM 2376 CE2 TRP A 307 22.170 28.738 18.411 1.00 14.58 C ATOM 2377 CE3 TRP A 307 20.173 28.447 19.766 1.00 12.51 C ATOM 2378 CZ2 TRP A 307 22.992 28.836 19.560 1.00 14.73 C ATOM 2379 CZ3 TRP A 307 20.916 28.515 20.870 1.00 14.68 C ATOM 2380 CH2 TRP A 307 22.344 28.717 20.816 1.00 15.64 C ATOM 2381 N GLY A 308 15.955 29.147 15.251 1.00 17.06 N ATOM 2382 CA GLY A 308 14.664 28.708 14.743 1.00 17.58 C ATOM 2383 C GLY A 308 13.953 27.768 15.698 1.00 17.29 C ATOM 2384 O GLY A 308 14.108 27.868 16.914 1.00 17.20 O ATOM 2385 N PRO A 309 13.090 26.923 15.105 1.00 17.62 N ATOM 2386 CA PRO A 309 12.079 26.375 16.013 1.00 16.63 C ATOM 2387 C PRO A 309 12.625 25.273 16.904 1.00 15.63 C ATOM 2388 O PRO A 309 11.914 24.887 17.822 1.00 16.64 O ATOM 2389 CB PRO A 309 11.010 25.809 15.058 1.00 18.12 C ATOM 2390 CG PRO A 309 11.470 26.073 13.666 1.00 22.71 C ATOM 2391 CD PRO A 309 12.647 26.971 13.696 1.00 17.37 C ATOM 2392 N TYR A 310 13.868 24.826 16.650 1.00 15.11 N ATOM 2393 CA TYR A 310 14.501 23.838 17.584 1.00 15.75 C ATOM 2394 C TYR A 310 15.634 24.563 18.324 1.00 14.17 C ATOM 2395 O TYR A 310 16.634 23.921 18.688 1.00 13.60 O ATOM 2396 CB TYR A 310 15.027 22.599 16.876 1.00 13.95 C ATOM 2397 CG TYR A 310 13.953 21.590 16.485 1.00 16.28 C ATOM 2398 CD1 TYR A 310 12.975 21.931 15.538 1.00 19.06 C ATOM 2399 CD2 TYR A 310 13.872 20.346 17.116 1.00 19.91 C ATOM 2400 CE1 TYR A 310 11.982 21.070 15.249 1.00 20.91 C ATOM 2401 CE2 TYR A 310 12.878 19.442 16.793 1.00 19.81 C ATOM 2402 CZ TYR A 310 11.953 19.837 15.850 1.00 21.68 C ATOM 2403 OH TYR A 310 10.925 18.934 15.553 1.00 22.66 O ATOM 2404 N ALA A 311 15.457 25.840 18.641 1.00 14.59 N ATOM 2405 CA ALA A 311 16.499 26.601 19.327 1.00 14.52 C ATOM 2406 C ALA A 311 16.866 25.977 20.687 1.00 16.13 C ATOM 2407 O ALA A 311 18.009 26.137 21.149 1.00 14.96 O ATOM 2408 CB ALA A 311 16.076 28.101 19.543 1.00 15.77 C ATOM 2409 N GLY A 312 15.890 25.323 21.346 1.00 14.53 N ATOM 2410 CA GLY A 312 16.265 24.846 22.676 1.00 14.16 C ATOM 2411 C GLY A 312 17.180 23.651 22.462 1.00 13.00 C ATOM 2412 O GLY A 312 18.040 23.379 23.347 1.00 13.09 O ATOM 2413 N TRP A 313 17.040 22.869 21.394 1.00 12.97 N ATOM 2414 CA TRP A 313 17.985 21.809 21.132 1.00 13.23 C ATOM 2415 C TRP A 313 19.395 22.348 20.903 1.00 13.42 C ATOM 2416 O TRP A 313 20.385 21.760 21.324 1.00 13.93 O ATOM 2417 CB TRP A 313 17.520 20.937 19.982 1.00 13.80 C ATOM 2418 CG TRP A 313 16.271 20.142 20.226 1.00 13.28 C ATOM 2419 CD1 TRP A 313 15.082 20.547 20.675 1.00 16.93 C ATOM 2420 CD2 TRP A 313 16.205 18.708 20.000 1.00 14.31 C ATOM 2421 NE1 TRP A 313 14.180 19.423 20.746 1.00 15.64 N ATOM 2422 CE2 TRP A 313 14.880 18.313 20.313 1.00 14.59 C ATOM 2423 CE3 TRP A 313 17.138 17.754 19.542 1.00 12.06 C ATOM 2424 CZ2 TRP A 313 14.464 16.950 20.204 1.00 14.10 C ATOM 2425 CZ3 TRP A 313 16.726 16.352 19.414 1.00 16.15 C ATOM 2426 CH2 TRP A 313 15.377 16.024 19.777 1.00 16.50 C ATOM 2427 N ALA A 314 19.517 23.440 20.136 1.00 11.24 N ATOM 2428 CA ALA A 314 20.839 23.978 19.879 1.00 11.47 C ATOM 2429 C ALA A 314 21.428 24.526 21.170 1.00 12.67 C ATOM 2430 O ALA A 314 22.624 24.370 21.338 1.00 13.71 O ATOM 2431 CB ALA A 314 20.662 25.103 18.809 1.00 11.81 C ATOM 2432 N GLN A 315 20.599 25.186 22.003 1.00 13.32 N ATOM 2433 CA GLN A 315 21.060 25.593 23.331 1.00 13.16 C ATOM 2434 C GLN A 315 21.651 24.400 24.114 1.00 13.37 C ATOM 2435 O GLN A 315 22.693 24.573 24.794 1.00 12.99 O ATOM 2436 CB GLN A 315 19.888 26.110 24.125 1.00 13.58 C ATOM 2437 CG GLN A 315 20.081 26.377 25.640 1.00 13.24 C ATOM 2438 CD GLN A 315 19.762 25.182 26.577 1.00 13.66 C ATOM 2439 OE1 GLN A 315 20.188 25.242 27.693 1.00 14.40 O ATOM 2440 NE2 GLN A 315 18.967 24.171 26.121 1.00 13.95 N ATOM 2441 N ALA A 316 21.042 23.213 23.975 1.00 13.16 N ATOM 2442 CA ALA A 316 21.602 22.060 24.717 1.00 13.28 C ATOM 2443 C ALA A 316 22.974 21.652 24.230 1.00 12.91 C ATOM 2444 O ALA A 316 23.814 21.235 25.052 1.00 13.78 O ATOM 2445 CB ALA A 316 20.611 20.872 24.656 1.00 13.10 C ATOM 2446 N VAL A 317 23.283 21.807 22.923 1.00 13.60 N ATOM 2447 CA VAL A 317 24.632 21.540 22.408 1.00 13.25 C ATOM 2448 C VAL A 317 25.597 22.563 23.036 1.00 13.08 C ATOM 2449 O VAL A 317 26.617 22.137 23.599 1.00 13.66 O ATOM 2450 CB VAL A 317 24.657 21.672 20.859 1.00 13.85 C ATOM 2451 CG1 VAL A 317 26.042 21.380 20.410 1.00 14.18 C ATOM 2452 CG2 VAL A 317 23.677 20.715 20.218 1.00 16.22 C ATOM 2453 N LEU A 318 25.281 23.873 23.011 1.00 12.52 N ATOM 2454 CA LEU A 318 26.277 24.826 23.503 1.00 13.68 C ATOM 2455 C LEU A 318 26.387 24.735 24.991 1.00 13.68 C ATOM 2456 O LEU A 318 27.436 24.909 25.546 1.00 14.73 O ATOM 2457 CB LEU A 318 26.003 26.280 23.011 1.00 14.03 C ATOM 2458 CG LEU A 318 26.024 26.426 21.474 1.00 15.59 C ATOM 2459 CD1 LEU A 318 26.133 27.948 21.223 1.00 17.02 C ATOM 2460 CD2 LEU A 318 27.228 25.698 20.898 1.00 18.62 C ATOM 2461 N PHE A 319 25.286 24.390 25.682 1.00 13.53 N ATOM 2462 CA PHE A 319 25.371 24.265 27.162 1.00 15.77 C ATOM 2463 C PHE A 319 26.269 23.069 27.513 1.00 13.68 C ATOM 2464 O PHE A 319 27.190 23.201 28.368 1.00 15.42 O ATOM 2465 CB PHE A 319 23.947 24.088 27.727 1.00 14.33 C ATOM 2466 CG PHE A 319 23.901 23.953 29.241 1.00 13.18 C ATOM 2467 CD1 PHE A 319 23.775 25.117 30.040 1.00 13.57 C ATOM 2468 CD2 PHE A 319 24.000 22.713 29.839 1.00 12.97 C ATOM 2469 CE1 PHE A 319 23.756 24.997 31.452 1.00 15.44 C ATOM 2470 CE2 PHE A 319 24.011 22.633 31.229 1.00 15.05 C ATOM 2471 CZ PHE A 319 23.873 23.743 32.044 1.00 14.16 C ATOM 2472 N SER A 320 26.066 21.915 26.862 1.00 15.49 N ATOM 2473 CA SER A 320 26.943 20.704 27.068 1.00 16.73 C ATOM 2474 C SER A 320 28.404 21.035 26.778 1.00 20.20 C ATOM 2475 O SER A 320 29.302 20.700 27.580 1.00 19.97 O ATOM 2476 CB SER A 320 26.469 19.569 26.170 1.00 18.55 C ATOM 2477 OG SER A 320 27.285 18.391 26.376 1.00 23.05 O ATOM 2478 N ALA A 321 28.644 21.756 25.681 1.00 19.19 N ATOM 2479 CA ALA A 321 29.996 22.263 25.440 1.00 21.55 C ATOM 2480 C ALA A 321 30.567 23.228 26.506 1.00 22.04 C ATOM 2481 O ALA A 321 31.799 23.167 26.759 1.00 26.16 O ATOM 2482 CB ALA A 321 30.021 22.950 24.060 1.00 20.24 C ATOM 2483 N ASP A 322 29.742 24.050 27.157 1.00 23.53 N ATOM 2484 CA ASP A 322 30.162 25.071 28.137 1.00 25.05 C ATOM 2485 C ASP A 322 30.630 24.368 29.420 1.00 27.88 C ATOM 2486 O ASP A 322 31.605 24.799 30.061 1.00 30.60 O ATOM 2487 CB ASP A 322 29.095 26.176 28.389 1.00 25.01 C ATOM 2488 CG ASP A 322 29.668 27.492 29.059 1.00 27.38 C ATOM 2489 OD1 ASP A 322 30.784 27.936 28.652 1.00 23.25 O ATOM 2490 OD2 ASP A 322 28.985 28.201 29.915 1.00 25.89 O ATOM 2491 N LEU A 323 29.995 23.252 29.747 1.00 28.33 N ATOM 2492 CA LEU A 323 30.374 22.466 30.910 1.00 30.17 C ATOM 2493 C LEU A 323 31.774 21.837 30.754 1.00 35.40 C ATOM 2494 O LEU A 323 32.480 21.690 31.747 1.00 35.55 O ATOM 2495 CB LEU A 323 29.357 21.351 31.121 1.00 27.48 C ATOM 2496 CG LEU A 323 27.924 21.750 31.455 1.00 21.67 C ATOM 2497 CD1 LEU A 323 27.193 20.417 31.536 1.00 20.87 C ATOM 2498 CD2 LEU A 323 27.717 22.460 32.759 1.00 23.82 C ATOM 2499 N ARG A 324 32.167 21.462 29.529 1.00 39.33 N ATOM 2500 CA ARG A 324 33.509 20.868 29.286 1.00 43.83 C ATOM 2501 C ARG A 324 34.614 21.932 29.228 1.00 46.62 C ATOM 2502 O ARG A 324 35.128 22.229 28.152 1.00 47.27 O ATOM 2503 CB ARG A 324 33.531 20.028 28.001 1.00 43.40 C ATOM 2504 CG ARG A 324 33.095 18.598 28.165 1.00 44.40 C ATOM 2505 CD ARG A 324 31.616 18.476 27.970 1.00 40.46 C ATOM 2506 NE ARG A 324 31.090 17.186 28.408 1.00 41.16 N ATOM 2507 CZ ARG A 324 29.839 16.994 28.829 1.00 40.96 C ATOM 2508 NH1 ARG A 324 29.450 15.778 29.207 1.00 40.54 N ATOM 2509 NH2 ARG A 324 28.966 18.002 28.861 1.00 26.61 N ATOM 2510 N GLN A 325 34.960 22.491 30.393 1.00 49.76 N ATOM 2511 CA GLN A 325 35.955 23.557 30.508 1.00 51.99 C ATOM 2512 C GLN A 325 37.329 23.067 30.980 1.00 52.60 C ATOM 2513 O GLN A 325 37.658 23.149 32.172 1.00 53.67 O ATOM 2514 CB GLN A 325 35.415 24.667 31.423 1.00 53.08 C ATOM 2515 CG GLN A 325 35.190 26.039 30.746 1.00 55.54 C ATOM 2516 CD GLN A 325 35.115 25.995 29.215 1.00 58.56 C ATOM 2517 OE1 GLN A 325 35.946 26.599 28.530 1.00 59.92 O ATOM 2518 NE2 GLN A 325 34.121 25.298 28.680 1.00 59.58 N TER 2519 GLN A 325 ATOM 2520 P DG B 2 9.689 46.755 33.034 1.00 92.51 P ATOM 2521 OP1 DG B 2 9.495 47.852 32.056 1.00 92.98 O ATOM 2522 OP2 DG B 2 9.672 45.369 32.517 1.00 92.60 O ATOM 2523 O5' DG B 2 11.093 46.986 33.786 1.00 89.73 O ATOM 2524 C5' DG B 2 11.510 48.303 34.169 1.00 86.50 C ATOM 2525 C4' DG B 2 11.907 48.388 35.640 1.00 84.03 C ATOM 2526 O4' DG B 2 10.817 48.048 36.524 1.00 82.75 O ATOM 2527 C3' DG B 2 13.007 47.435 36.069 1.00 82.41 C ATOM 2528 O3' DG B 2 14.238 48.033 35.708 1.00 80.47 O ATOM 2529 C2' DG B 2 12.825 47.350 37.584 1.00 81.94 C ATOM 2530 C1' DG B 2 11.384 47.788 37.788 1.00 81.54 C ATOM 2531 N9 DG B 2 10.552 46.801 38.464 1.00 80.76 N ATOM 2532 C8 DG B 2 9.677 45.886 37.919 1.00 80.67 C ATOM 2533 N7 DG B 2 9.071 45.148 38.814 1.00 80.03 N ATOM 2534 C5 DG B 2 9.574 45.616 40.023 1.00 79.32 C ATOM 2535 C6 DG B 2 9.299 45.219 41.352 1.00 79.02 C ATOM 2536 O6 DG B 2 8.523 44.339 41.741 1.00 79.47 O ATOM 2537 N1 DG B 2 10.027 45.950 42.287 1.00 78.49 N ATOM 2538 C2 DG B 2 10.919 46.949 41.969 1.00 79.11 C ATOM 2539 N2 DG B 2 11.539 47.548 42.991 1.00 79.73 N ATOM 2540 N3 DG B 2 11.193 47.335 40.732 1.00 79.34 N ATOM 2541 C4 DG B 2 10.482 46.630 39.820 1.00 79.82 C ATOM 2542 P DT B 3 15.612 47.232 35.858 1.00 78.37 P ATOM 2543 OP1 DT B 3 16.623 47.950 35.037 1.00 78.10 O ATOM 2544 OP2 DT B 3 15.275 45.800 35.641 1.00 78.56 O ATOM 2545 O5' DT B 3 16.029 47.399 37.395 1.00 75.65 O ATOM 2546 C5' DT B 3 16.572 48.611 37.897 1.00 72.06 C ATOM 2547 C4' DT B 3 16.848 48.423 39.370 1.00 69.79 C ATOM 2548 O4' DT B 3 15.700 47.817 40.025 1.00 67.76 O ATOM 2549 C3' DT B 3 18.015 47.482 39.611 1.00 68.81 C ATOM 2550 O3' DT B 3 18.876 48.111 40.497 1.00 68.61 O ATOM 2551 C2' DT B 3 17.394 46.218 40.210 1.00 66.89 C ATOM 2552 C1' DT B 3 16.147 46.765 40.864 1.00 66.33 C ATOM 2553 N1 DT B 3 15.047 45.768 41.043 1.00 65.00 N ATOM 2554 C2 DT B 3 14.680 45.425 42.336 1.00 65.24 C ATOM 2555 O2 DT B 3 15.212 45.875 43.340 1.00 65.27 O ATOM 2556 N3 DT B 3 13.653 44.506 42.421 1.00 63.92 N ATOM 2557 C4 DT B 3 12.963 43.908 41.374 1.00 63.44 C ATOM 2558 O4 DT B 3 12.058 43.106 41.587 1.00 61.27 O ATOM 2559 C5 DT B 3 13.385 44.304 40.041 1.00 63.63 C ATOM 2560 C7 DT B 3 12.710 43.720 38.824 1.00 63.83 C ATOM 2561 C6 DT B 3 14.395 45.200 39.946 1.00 64.83 C ATOM 2562 P DA B 4 20.247 47.395 40.900 1.00 72.22 P ATOM 2563 OP1 DA B 4 21.293 48.140 40.163 1.00 72.62 O ATOM 2564 OP2 DA B 4 20.137 45.920 40.731 1.00 72.57 O ATOM 2565 O5' DA B 4 20.423 47.657 42.488 1.00 69.73 O ATOM 2566 C5' DA B 4 19.315 47.656 43.411 1.00 66.20 C ATOM 2567 C4' DA B 4 19.399 46.547 44.456 1.00 63.65 C ATOM 2568 O4' DA B 4 18.274 45.650 44.294 1.00 62.52 O ATOM 2569 C3' DA B 4 20.630 45.637 44.466 1.00 63.86 C ATOM 2570 O3' DA B 4 21.035 45.500 45.826 1.00 66.09 O ATOM 2571 C2' DA B 4 20.139 44.301 43.886 1.00 61.32 C ATOM 2572 C1' DA B 4 18.699 44.297 44.380 1.00 58.44 C ATOM 2573 N9 DA B 4 17.746 43.477 43.630 1.00 54.23 N ATOM 2574 C8 DA B 4 17.723 43.217 42.287 1.00 51.63 C ATOM 2575 N7 DA B 4 16.721 42.440 41.932 1.00 51.73 N ATOM 2576 C5 DA B 4 16.032 42.161 43.109 1.00 49.67 C ATOM 2577 C6 DA B 4 14.869 41.403 43.424 1.00 49.11 C ATOM 2578 N6 DA B 4 14.106 40.712 42.561 1.00 47.47 N ATOM 2579 N1 DA B 4 14.487 41.375 44.711 1.00 49.65 N ATOM 2580 C2 DA B 4 15.195 42.032 45.636 1.00 50.92 C ATOM 2581 N3 DA B 4 16.281 42.779 45.460 1.00 51.27 N ATOM 2582 C4 DA B 4 16.656 42.804 44.165 1.00 51.95 C ATOM 2583 P DG B 5 22.555 45.233 46.276 1.00 67.33 P ATOM 2584 OP1 DG B 5 23.044 46.488 46.899 1.00 66.76 O ATOM 2585 OP2 DG B 5 23.271 44.547 45.165 1.00 66.12 O ATOM 2586 O5' DG B 5 22.417 44.154 47.473 1.00 65.22 O ATOM 2587 C5' DG B 5 21.320 44.268 48.389 1.00 59.59 C ATOM 2588 C4' DG B 5 20.784 42.901 48.765 1.00 55.14 C ATOM 2589 O4' DG B 5 19.860 42.399 47.769 1.00 51.87 O ATOM 2590 C3' DG B 5 21.839 41.817 48.949 1.00 54.13 C ATOM 2591 O3' DG B 5 21.485 41.232 50.194 1.00 55.64 O ATOM 2592 C2' DG B 5 21.646 40.873 47.754 1.00 51.98 C ATOM 2593 C1' DG B 5 20.143 41.024 47.557 1.00 48.37 C ATOM 2594 N9 DG B 5 19.588 40.611 46.263 1.00 45.06 N ATOM 2595 C8 DG B 5 20.042 40.838 44.979 1.00 42.76 C ATOM 2596 N7 DG B 5 19.244 40.336 44.061 1.00 42.39 N ATOM 2597 C5 DG B 5 18.199 39.746 44.775 1.00 39.35 C ATOM 2598 C6 DG B 5 17.056 39.027 44.360 1.00 37.91 C ATOM 2599 O6 DG B 5 16.676 38.760 43.225 1.00 38.25 O ATOM 2600 N1 DG B 5 16.244 38.599 45.406 1.00 37.68 N ATOM 2601 C2 DG B 5 16.524 38.847 46.721 1.00 39.26 C ATOM 2602 N2 DG B 5 15.652 38.339 47.606 1.00 37.43 N ATOM 2603 N3 DG B 5 17.610 39.499 47.141 1.00 39.89 N ATOM 2604 C4 DG B 5 18.397 39.922 46.125 1.00 41.87 C ATOM 2605 P DA B 6 22.425 40.328 51.127 1.00 57.05 P ATOM 2606 OP1 DA B 6 22.590 41.051 52.411 1.00 56.30 O ATOM 2607 OP2 DA B 6 23.559 39.791 50.344 1.00 54.39 O ATOM 2608 O5' DA B 6 21.430 39.152 51.542 1.00 52.59 O ATOM 2609 C5' DA B 6 20.133 39.520 52.018 1.00 45.83 C ATOM 2610 C4' DA B 6 19.314 38.264 52.123 1.00 40.67 C ATOM 2611 O4' DA B 6 18.784 37.858 50.837 1.00 39.74 O ATOM 2612 C3' DA B 6 20.038 37.028 52.628 1.00 38.82 C ATOM 2613 O3' DA B 6 19.024 36.375 53.374 1.00 36.67 O ATOM 2614 C2' DA B 6 20.387 36.232 51.348 1.00 33.53 C ATOM 2615 C1' DA B 6 19.201 36.538 50.452 1.00 34.10 C ATOM 2616 N9 DA B 6 19.430 36.632 48.995 1.00 31.07 N ATOM 2617 C8 DA B 6 20.524 37.237 48.405 1.00 33.63 C ATOM 2618 N7 DA B 6 20.465 37.234 47.094 1.00 29.97 N ATOM 2619 C5 DA B 6 19.289 36.566 46.790 1.00 31.04 C ATOM 2620 C6 DA B 6 18.692 36.223 45.562 1.00 28.93 C ATOM 2621 N6 DA B 6 19.349 36.567 44.391 1.00 26.11 N ATOM 2622 N1 DA B 6 17.476 35.575 45.540 1.00 26.47 N ATOM 2623 C2 DA B 6 16.943 35.219 46.719 1.00 30.69 C ATOM 2624 N3 DA B 6 17.437 35.501 47.945 1.00 29.77 N ATOM 2625 C4 DA B 6 18.632 36.157 47.953 1.00 30.15 C ATOM 2626 P DC B 7 19.471 35.182 54.326 1.00 38.40 P ATOM 2627 OP1 DC B 7 18.479 35.175 55.430 1.00 37.30 O ATOM 2628 OP2 DC B 7 20.905 35.167 54.569 1.00 30.55 O ATOM 2629 O5' DC B 7 19.232 33.831 53.422 1.00 35.59 O ATOM 2630 C5' DC B 7 17.991 33.393 53.106 1.00 30.96 C ATOM 2631 C4' DC B 7 18.173 32.301 52.050 1.00 29.48 C ATOM 2632 O4' DC B 7 18.661 32.954 50.854 1.00 29.89 O ATOM 2633 C3' DC B 7 19.221 31.240 52.373 1.00 32.33 C ATOM 2634 O3' DC B 7 18.648 29.938 52.273 1.00 32.06 O ATOM 2635 C2' DC B 7 20.307 31.430 51.316 1.00 30.37 C ATOM 2636 C1' DC B 7 19.447 31.976 50.207 1.00 28.77 C ATOM 2637 N1 DC B 7 20.203 32.672 49.108 1.00 27.04 N ATOM 2638 C2 DC B 7 19.722 32.567 47.793 1.00 27.03 C ATOM 2639 O2 DC B 7 18.696 31.975 47.498 1.00 26.54 O ATOM 2640 N3 DC B 7 20.429 33.221 46.809 1.00 26.78 N ATOM 2641 C4 DC B 7 21.535 33.882 47.081 1.00 26.23 C ATOM 2642 N4 DC B 7 22.177 34.511 46.084 1.00 30.31 N ATOM 2643 C5 DC B 7 22.028 34.013 48.414 1.00 28.71 C ATOM 2644 C6 DC B 7 21.318 33.361 49.392 1.00 24.39 C ATOM 2645 P DC B 8 17.607 29.392 53.410 1.00 33.62 P ATOM 2646 OP1 DC B 8 16.292 29.678 52.978 1.00 27.07 O ATOM 2647 OP2 DC B 8 18.140 29.964 54.679 1.00 32.54 O ATOM 2648 O5' DC B 8 17.984 27.848 53.462 1.00 28.61 O ATOM 2649 C5' DC B 8 19.303 27.508 53.772 1.00 26.55 C ATOM 2650 C4' DC B 8 19.462 26.076 53.317 1.00 26.54 C ATOM 2651 O4' DC B 8 19.482 26.097 51.845 1.00 22.78 O ATOM 2652 C3' DC B 8 20.733 25.394 53.781 1.00 24.34 C ATOM 2653 O3' DC B 8 20.535 23.978 53.949 1.00 24.67 O ATOM 2654 C2' DC B 8 21.729 25.675 52.647 1.00 25.84 C ATOM 2655 C1' DC B 8 20.754 25.605 51.497 1.00 22.86 C ATOM 2656 N1 DC B 8 21.234 26.335 50.252 1.00 23.66 N ATOM 2657 C2 DC B 8 21.057 25.622 49.035 1.00 25.71 C ATOM 2658 O2 DC B 8 20.515 24.503 49.021 1.00 22.36 O ATOM 2659 N3 DC B 8 21.564 26.210 47.887 1.00 21.38 N ATOM 2660 C4 DC B 8 22.098 27.444 47.959 1.00 24.58 C ATOM 2661 N4 DC B 8 22.552 27.998 46.800 1.00 23.64 N ATOM 2662 C5 DC B 8 22.274 28.187 49.187 1.00 25.05 C ATOM 2663 C6 DC B 8 21.841 27.584 50.343 1.00 26.09 C ATOM 2664 P DT B 9 21.644 22.964 54.487 1.00 29.27 P ATOM 2665 OP1 DT B 9 21.074 21.642 54.783 1.00 31.02 O ATOM 2666 OP2 DT B 9 22.484 23.672 55.463 1.00 28.10 O ATOM 2667 O5' DT B 9 22.714 22.843 53.261 1.00 28.58 O ATOM 2668 C5' DT B 9 22.339 21.888 52.260 1.00 29.48 C ATOM 2669 C4' DT B 9 23.455 21.819 51.233 1.00 26.64 C ATOM 2670 O4' DT B 9 23.577 23.134 50.649 1.00 25.82 O ATOM 2671 C3' DT B 9 24.855 21.497 51.805 1.00 28.72 C ATOM 2672 O3' DT B 9 25.216 20.168 51.461 1.00 34.86 O ATOM 2673 C2' DT B 9 25.798 22.547 51.243 1.00 29.26 C ATOM 2674 C1' DT B 9 24.932 23.215 50.181 1.00 26.75 C ATOM 2675 N1 DT B 9 25.172 24.639 49.803 1.00 25.99 N ATOM 2676 C2 DT B 9 25.394 24.933 48.457 1.00 26.13 C ATOM 2677 O2 DT B 9 25.467 24.023 47.653 1.00 23.19 O ATOM 2678 N3 DT B 9 25.525 26.291 48.187 1.00 26.05 N ATOM 2679 C4 DT B 9 25.441 27.324 49.084 1.00 28.09 C ATOM 2680 O4 DT B 9 25.547 28.507 48.777 1.00 25.15 O ATOM 2681 C5 DT B 9 25.206 26.960 50.471 1.00 30.75 C ATOM 2682 C7 DT B 9 25.161 28.074 51.487 1.00 29.49 C ATOM 2683 C6 DT B 9 25.082 25.671 50.759 1.00 25.22 C ATOM 2684 P DG B 10 26.450 19.455 52.229 1.00 36.98 P ATOM 2685 OP1 DG B 10 26.211 17.997 52.223 1.00 41.23 O ATOM 2686 OP2 DG B 10 26.663 20.123 53.519 1.00 36.78 O ATOM 2687 O5' DG B 10 27.693 19.742 51.255 1.00 39.24 O ATOM 2688 C5' DG B 10 27.673 19.194 49.912 1.00 38.49 C ATOM 2689 C4' DG B 10 28.802 19.760 49.090 1.00 40.54 C ATOM 2690 O4' DG B 10 28.483 21.162 48.835 1.00 37.55 O ATOM 2691 C3' DG B 10 30.159 19.780 49.805 1.00 40.88 C ATOM 2692 O3' DG B 10 31.103 19.737 48.800 1.00 48.08 O ATOM 2693 C2' DG B 10 30.218 21.173 50.401 1.00 42.12 C ATOM 2694 C1' DG B 10 29.605 21.934 49.221 1.00 39.76 C ATOM 2695 N9 DG B 10 29.257 23.301 49.564 1.00 37.80 N ATOM 2696 C8 DG B 10 28.966 23.854 50.795 1.00 37.93 C ATOM 2697 N7 DG B 10 28.738 25.136 50.738 1.00 38.34 N ATOM 2698 C5 DG B 10 28.897 25.463 49.396 1.00 35.02 C ATOM 2699 C6 DG B 10 28.782 26.688 48.718 1.00 34.88 C ATOM 2700 O6 DG B 10 28.504 27.807 49.169 1.00 34.87 O ATOM 2701 N1 DG B 10 29.054 26.562 47.354 1.00 34.16 N ATOM 2702 C2 DG B 10 29.356 25.402 46.717 1.00 34.57 C ATOM 2703 N2 DG B 10 29.559 25.482 45.387 1.00 32.64 N ATOM 2704 N3 DG B 10 29.463 24.228 47.348 1.00 35.27 N ATOM 2705 C4 DG B 10 29.219 24.346 48.674 1.00 38.75 C ATOM 2706 P DG B 11 32.289 18.696 48.860 1.00 50.71 P ATOM 2707 OP1 DG B 11 31.697 17.351 48.800 1.00 48.75 O ATOM 2708 OP2 DG B 11 33.196 19.137 49.968 1.00 51.39 O ATOM 2709 O5' DG B 11 33.072 19.019 47.502 1.00 50.80 O ATOM 2710 C5' DG B 11 32.490 18.872 46.202 1.00 49.34 C ATOM 2711 C4' DG B 11 33.249 19.836 45.326 1.00 49.94 C ATOM 2712 O4' DG B 11 32.829 21.170 45.668 1.00 46.62 O ATOM 2713 C3' DG B 11 34.765 19.796 45.541 1.00 51.80 C ATOM 2714 O3' DG B 11 35.356 19.778 44.243 1.00 56.83 O ATOM 2715 C2' DG B 11 35.073 21.027 46.410 1.00 49.21 C ATOM 2716 C1' DG B 11 33.943 21.976 46.012 1.00 46.36 C ATOM 2717 N9 DG B 11 33.482 22.894 47.041 1.00 42.34 N ATOM 2718 C8 DG B 11 33.152 22.590 48.344 1.00 41.73 C ATOM 2719 N7 DG B 11 32.745 23.626 49.018 1.00 42.50 N ATOM 2720 C5 DG B 11 32.795 24.668 48.093 1.00 40.99 C ATOM 2721 C6 DG B 11 32.480 26.038 48.225 1.00 40.19 C ATOM 2722 O6 DG B 11 32.059 26.627 49.219 1.00 42.36 O ATOM 2723 N1 DG B 11 32.679 26.763 47.059 1.00 40.65 N ATOM 2724 C2 DG B 11 33.116 26.226 45.884 1.00 39.93 C ATOM 2725 N2 DG B 11 33.234 27.067 44.850 1.00 42.49 N ATOM 2726 N3 DG B 11 33.420 24.957 45.733 1.00 39.70 N ATOM 2727 C4 DG B 11 33.251 24.234 46.874 1.00 40.92 C ATOM 2728 P DA B 12 36.858 20.224 43.875 1.00 60.83 P ATOM 2729 OP1 DA B 12 37.111 19.596 42.550 1.00 61.76 O ATOM 2730 OP2 DA B 12 37.743 20.000 45.048 1.00 60.51 O ATOM 2731 O5' DA B 12 36.774 21.816 43.664 1.00 60.59 O ATOM 2732 C5' DA B 12 36.380 22.350 42.424 1.00 61.10 C ATOM 2733 C4' DA B 12 36.924 23.749 42.290 1.00 62.42 C ATOM 2734 O4' DA B 12 36.447 24.596 43.367 1.00 61.07 O ATOM 2735 C3' DA B 12 38.441 23.843 42.330 1.00 63.92 C ATOM 2736 O3' DA B 12 38.792 24.719 41.269 1.00 67.79 O ATOM 2737 C2' DA B 12 38.778 24.403 43.722 1.00 61.13 C ATOM 2738 C1' DA B 12 37.525 25.212 44.048 1.00 58.43 C ATOM 2739 N9 DA B 12 37.101 25.200 45.443 1.00 54.34 N ATOM 2740 C8 DA B 12 37.064 24.114 46.277 1.00 51.10 C ATOM 2741 N7 DA B 12 36.614 24.412 47.474 1.00 51.49 N ATOM 2742 C5 DA B 12 36.330 25.782 47.416 1.00 49.95 C ATOM 2743 C6 DA B 12 35.822 26.728 48.353 1.00 49.45 C ATOM 2744 N6 DA B 12 35.480 26.420 49.608 1.00 50.11 N ATOM 2745 N1 DA B 12 35.665 28.024 47.962 1.00 49.36 N ATOM 2746 C2 DA B 12 36.004 28.357 46.702 1.00 48.37 C ATOM 2747 N3 DA B 12 36.494 27.563 45.733 1.00 50.15 N ATOM 2748 C4 DA B 12 36.622 26.280 46.154 1.00 51.36 C ATOM 2749 P DC B 13 40.317 25.115 41.024 1.00 71.85 P ATOM 2750 OP1 DC B 13 40.404 25.549 39.607 1.00 71.92 O ATOM 2751 OP2 DC B 13 41.137 24.000 41.571 1.00 70.41 O ATOM 2752 O5' DC B 13 40.536 26.407 41.949 1.00 70.76 O ATOM 2753 C5' DC B 13 39.862 27.623 41.637 1.00 71.51 C ATOM 2754 C4' DC B 13 40.143 28.642 42.723 1.00 71.91 C ATOM 2755 O4' DC B 13 39.501 28.253 43.963 1.00 71.43 O ATOM 2756 C3' DC B 13 41.622 28.756 43.086 1.00 73.18 C ATOM 2757 O3' DC B 13 41.917 30.088 43.356 1.00 76.28 O ATOM 2758 C2' DC B 13 41.779 27.973 44.375 1.00 71.01 C ATOM 2759 C1' DC B 13 40.466 28.447 44.977 1.00 68.61 C ATOM 2760 N1 DC B 13 40.100 27.784 46.235 1.00 64.71 N ATOM 2761 C2 DC B 13 39.552 28.589 47.242 1.00 62.43 C ATOM 2762 O2 DC B 13 39.384 29.803 47.027 1.00 61.46 O ATOM 2763 N3 DC B 13 39.221 28.000 48.419 1.00 60.25 N ATOM 2764 C4 DC B 13 39.427 26.690 48.599 1.00 61.11 C ATOM 2765 N4 DC B 13 39.076 26.176 49.786 1.00 60.04 N ATOM 2766 C5 DC B 13 39.990 25.849 47.579 1.00 61.82 C ATOM 2767 C6 DC B 13 40.311 26.437 46.418 1.00 63.58 C ATOM 2768 P DG B 14 43.245 30.625 42.675 1.00 79.03 P ATOM 2769 OP1 DG B 14 42.845 31.042 41.303 1.00 78.36 O ATOM 2770 OP2 DG B 14 44.289 29.587 42.873 1.00 77.77 O ATOM 2771 O5' DG B 14 43.629 31.902 43.577 1.00 79.44 O ATOM 2772 C5' DG B 14 42.812 33.076 43.657 1.00 79.93 C ATOM 2773 C4' DG B 14 42.955 33.661 45.050 1.00 80.65 C ATOM 2774 O4' DG B 14 42.138 32.847 45.932 1.00 79.52 O ATOM 2775 C3' DG B 14 44.363 33.617 45.662 1.00 81.84 C ATOM 2776 O3' DG B 14 45.186 34.780 45.375 1.00 85.90 O ATOM 2777 C2' DG B 14 44.096 33.464 47.155 1.00 79.66 C ATOM 2778 C1' DG B 14 42.746 32.757 47.211 1.00 77.39 C ATOM 2779 N9 DG B 14 42.805 31.351 47.626 1.00 72.54 N ATOM 2780 C8 DG B 14 43.250 30.268 46.900 1.00 71.26 C ATOM 2781 N7 DG B 14 43.165 29.137 47.555 1.00 69.29 N ATOM 2782 C5 DG B 14 42.628 29.495 48.795 1.00 68.05 C ATOM 2783 C6 DG B 14 42.304 28.702 49.935 1.00 66.94 C ATOM 2784 O6 DG B 14 42.423 27.471 50.084 1.00 66.01 O ATOM 2785 N1 DG B 14 41.786 29.471 50.985 1.00 65.03 N ATOM 2786 C2 DG B 14 41.605 30.833 50.939 1.00 65.82 C ATOM 2787 N2 DG B 14 41.095 31.389 52.049 1.00 66.31 N ATOM 2788 N3 DG B 14 41.903 31.592 49.886 1.00 66.75 N ATOM 2789 C4 DG B 14 42.406 30.860 48.852 1.00 69.25 C ATOM 2790 P DC B 15 44.937 36.278 45.938 1.00 89.45 P ATOM 2791 OP1 DC B 15 43.489 36.610 45.864 1.00 89.25 O ATOM 2792 OP2 DC B 15 45.905 37.156 45.235 1.00 89.58 O ATOM 2793 O5' DC B 15 45.384 36.221 47.474 1.00 89.40 O ATOM 2794 C5' DC B 15 44.854 37.133 48.444 1.00 90.14 C ATOM 2795 C4' DC B 15 45.242 36.623 49.820 1.00 90.91 C ATOM 2796 O4' DC B 15 44.796 35.250 49.924 1.00 90.17 O ATOM 2797 C3' DC B 15 46.748 36.576 50.088 1.00 90.94 C ATOM 2798 O3' DC B 15 47.156 37.756 50.760 1.00 92.01 O ATOM 2799 C2' DC B 15 46.945 35.359 50.985 1.00 90.30 C ATOM 2800 C1' DC B 15 45.649 34.557 50.814 1.00 89.96 C ATOM 2801 N1 DC B 15 45.840 33.149 50.313 1.00 88.82 N ATOM 2802 C2 DC B 15 45.276 32.070 51.034 1.00 88.40 C ATOM 2803 O2 DC B 15 44.624 32.272 52.073 1.00 88.31 O ATOM 2804 N3 DC B 15 45.462 30.803 50.572 1.00 87.72 N ATOM 2805 C4 DC B 15 46.163 30.586 49.449 1.00 87.95 C ATOM 2806 N4 DC B 15 46.307 29.313 49.050 1.00 87.30 N ATOM 2807 C5 DC B 15 46.745 31.670 48.699 1.00 88.23 C ATOM 2808 C6 DC B 15 46.563 32.917 49.166 1.00 88.62 C TER 2809 DC B 15 ATOM 2810 P DG C 16 42.442 24.972 60.459 1.00119.89 P ATOM 2811 OP1 DG C 16 42.168 24.841 61.913 1.00119.87 O ATOM 2812 OP2 DG C 16 41.315 25.142 59.514 1.00119.47 O ATOM 2813 O5' DG C 16 43.464 26.198 60.228 1.00118.47 O ATOM 2814 C5' DG C 16 43.340 27.489 60.868 1.00115.59 C ATOM 2815 C4' DG C 16 42.870 28.580 59.906 1.00113.51 C ATOM 2816 O4' DG C 16 43.753 28.729 58.753 1.00112.06 O ATOM 2817 C3' DG C 16 41.502 28.341 59.278 1.00112.60 C ATOM 2818 O3' DG C 16 40.441 28.644 60.197 1.00112.49 O ATOM 2819 C2' DG C 16 41.579 29.219 58.029 1.00111.20 C ATOM 2820 C1' DG C 16 42.996 28.901 57.556 1.00109.73 C ATOM 2821 N9 DG C 16 43.179 27.709 56.701 1.00106.98 N ATOM 2822 C8 DG C 16 42.969 26.383 57.031 1.00105.81 C ATOM 2823 N7 DG C 16 43.236 25.535 56.074 1.00104.54 N ATOM 2824 C5 DG C 16 43.663 26.345 55.034 1.00104.09 C ATOM 2825 C6 DG C 16 44.090 25.989 53.731 1.00103.33 C ATOM 2826 O6 DG C 16 44.170 24.851 53.249 1.00102.99 O ATOM 2827 N1 DG C 16 44.442 27.109 52.970 1.00102.60 N ATOM 2828 C2 DG C 16 44.385 28.412 53.428 1.00102.36 C ATOM 2829 N2 DG C 16 44.761 29.366 52.571 1.00101.32 N ATOM 2830 N3 DG C 16 43.985 28.760 54.647 1.00103.10 N ATOM 2831 C4 DG C 16 43.638 27.681 55.398 1.00104.83 C ATOM 2832 P DC C 17 39.511 27.445 60.743 1.00112.28 P ATOM 2833 OP1 DC C 17 40.247 26.788 61.850 1.00111.57 O ATOM 2834 OP2 DC C 17 39.080 26.660 59.554 1.00111.81 O ATOM 2835 O5' DC C 17 38.222 28.179 61.389 1.00110.41 O ATOM 2836 C5' DC C 17 37.067 28.540 60.620 1.00106.69 C ATOM 2837 C4' DC C 17 37.389 29.746 59.750 1.00103.81 C ATOM 2838 O4' DC C 17 38.446 29.455 58.786 1.00102.86 O ATOM 2839 C3' DC C 17 36.234 30.301 58.939 1.00101.93 C ATOM 2840 O3' DC C 17 36.337 31.719 59.131 1.00 99.82 O ATOM 2841 C2' DC C 17 36.542 29.772 57.531 1.00101.77 C ATOM 2842 C1' DC C 17 38.068 29.869 57.491 1.00101.28 C ATOM 2843 N1 DC C 17 38.800 29.083 56.396 1.00 99.62 N ATOM 2844 C2 DC C 17 39.523 29.767 55.388 1.00 98.52 C ATOM 2845 O2 DC C 17 39.577 31.006 55.384 1.00 98.10 O ATOM 2846 N3 DC C 17 40.163 29.050 54.423 1.00 97.29 N ATOM 2847 C4 DC C 17 40.112 27.713 54.426 1.00 97.21 C ATOM 2848 N4 DC C 17 40.760 27.056 53.454 1.00 96.37 N ATOM 2849 C5 DC C 17 39.389 26.996 55.433 1.00 97.58 C ATOM 2850 C6 DC C 17 38.759 27.709 56.383 1.00 98.72 C ATOM 2851 P DG C 18 36.043 32.845 58.026 1.00 98.48 P ATOM 2852 OP1 DG C 18 35.920 34.144 58.737 1.00 98.68 O ATOM 2853 OP2 DG C 18 34.904 32.358 57.200 1.00 98.95 O ATOM 2854 O5' DG C 18 37.387 32.878 57.127 1.00 95.44 O ATOM 2855 C5' DG C 18 38.032 34.086 56.648 1.00 89.16 C ATOM 2856 C4' DG C 18 37.472 34.590 55.316 1.00 84.59 C ATOM 2857 O4' DG C 18 37.772 33.691 54.208 1.00 81.73 O ATOM 2858 C3' DG C 18 35.963 34.830 55.271 1.00 82.64 C ATOM 2859 O3' DG C 18 35.738 36.108 54.681 1.00 82.56 O ATOM 2860 C2' DG C 18 35.404 33.639 54.473 1.00 80.34 C ATOM 2861 C1' DG C 18 36.578 33.214 53.593 1.00 78.24 C ATOM 2862 N9 DG C 18 36.736 31.768 53.387 1.00 73.37 N ATOM 2863 C8 DG C 18 36.387 30.722 54.224 1.00 72.26 C ATOM 2864 N7 DG C 18 36.676 29.534 53.754 1.00 70.25 N ATOM 2865 C5 DG C 18 37.267 29.812 52.519 1.00 69.15 C ATOM 2866 C6 DG C 18 37.799 28.946 51.528 1.00 67.26 C ATOM 2867 O6 DG C 18 37.862 27.713 51.546 1.00 66.96 O ATOM 2868 N1 DG C 18 38.308 29.636 50.425 1.00 66.81 N ATOM 2869 C2 DG C 18 38.304 31.006 50.277 1.00 67.43 C ATOM 2870 N2 DG C 18 38.838 31.497 49.143 1.00 66.69 N ATOM 2871 N3 DG C 18 37.815 31.834 51.197 1.00 68.58 N ATOM 2872 C4 DG C 18 37.313 31.177 52.282 1.00 70.47 C ATOM 2873 P DT C 19 34.350 36.465 53.970 1.00 83.06 P ATOM 2874 OP1 DT C 19 34.287 37.937 53.770 1.00 83.10 O ATOM 2875 OP2 DT C 19 33.281 35.759 54.729 1.00 82.83 O ATOM 2876 O5' DT C 19 34.524 35.817 52.508 1.00 80.26 O ATOM 2877 C5' DT C 19 35.607 36.264 51.670 1.00 75.51 C ATOM 2878 C4' DT C 19 35.447 35.804 50.232 1.00 71.20 C ATOM 2879 O4' DT C 19 35.654 34.377 50.163 1.00 69.27 O ATOM 2880 C3' DT C 19 34.097 36.093 49.585 1.00 69.86 C ATOM 2881 O3' DT C 19 34.404 36.691 48.330 1.00 69.51 O ATOM 2882 C2' DT C 19 33.438 34.716 49.472 1.00 68.49 C ATOM 2883 C1' DT C 19 34.636 33.766 49.399 1.00 66.81 C ATOM 2884 N1 DT C 19 34.464 32.382 49.981 1.00 63.32 N ATOM 2885 C2 DT C 19 34.940 31.260 49.300 1.00 61.28 C ATOM 2886 O2 DT C 19 35.487 31.291 48.213 1.00 61.42 O ATOM 2887 N3 DT C 19 34.742 30.055 49.938 1.00 60.93 N ATOM 2888 C4 DT C 19 34.133 29.864 51.169 1.00 60.48 C ATOM 2889 O4 DT C 19 34.010 28.741 51.651 1.00 61.02 O ATOM 2890 C5 DT C 19 33.667 31.068 51.836 1.00 61.59 C ATOM 2891 C7 DT C 19 32.998 30.998 53.184 1.00 61.07 C ATOM 2892 C6 DT C 19 33.854 32.249 51.218 1.00 62.05 C ATOM 2893 P DC C 20 33.345 37.318 47.293 1.00 69.62 P ATOM 2894 OP1 DC C 20 34.038 38.396 46.548 1.00 70.78 O ATOM 2895 OP2 DC C 20 32.039 37.581 47.943 1.00 68.68 O ATOM 2896 O5' DC C 20 33.229 36.126 46.247 1.00 65.93 O ATOM 2897 C5' DC C 20 34.387 35.827 45.456 1.00 61.21 C ATOM 2898 C4' DC C 20 34.105 34.649 44.543 1.00 56.98 C ATOM 2899 O4' DC C 20 33.993 33.430 45.322 1.00 53.76 O ATOM 2900 C3' DC C 20 32.805 34.763 43.757 1.00 54.78 C ATOM 2901 O3' DC C 20 33.104 34.378 42.434 1.00 53.41 O ATOM 2902 C2' DC C 20 31.822 33.843 44.486 1.00 51.15 C ATOM 2903 C1' DC C 20 32.787 32.769 44.968 1.00 51.66 C ATOM 2904 N1 DC C 20 32.373 31.943 46.150 1.00 47.39 N ATOM 2905 C2 DC C 20 32.665 30.576 46.097 1.00 46.22 C ATOM 2906 O2 DC C 20 33.225 30.086 45.089 1.00 48.56 O ATOM 2907 N3 DC C 20 32.325 29.812 47.153 1.00 45.59 N ATOM 2908 C4 DC C 20 31.715 30.342 48.230 1.00 43.06 C ATOM 2909 N4 DC C 20 31.426 29.480 49.207 1.00 42.20 N ATOM 2910 C5 DC C 20 31.403 31.730 48.325 1.00 43.56 C ATOM 2911 C6 DC C 20 31.756 32.494 47.261 1.00 45.50 C ATOM 2912 P DC C 21 32.074 34.828 41.299 1.00 56.80 P ATOM 2913 OP1 DC C 21 32.807 35.149 40.025 1.00 54.74 O ATOM 2914 OP2 DC C 21 31.072 35.719 41.927 1.00 51.59 O ATOM 2915 O5' DC C 21 31.393 33.411 41.019 1.00 52.63 O ATOM 2916 C5' DC C 21 32.270 32.389 40.577 1.00 46.68 C ATOM 2917 C4' DC C 21 31.532 31.110 40.875 1.00 44.37 C ATOM 2918 O4' DC C 21 31.157 31.092 42.259 1.00 42.24 O ATOM 2919 C3' DC C 21 30.192 31.039 40.142 1.00 43.07 C ATOM 2920 O3' DC C 21 30.373 30.086 39.087 1.00 42.30 O ATOM 2921 C2' DC C 21 29.182 30.660 41.226 1.00 41.96 C ATOM 2922 C1' DC C 21 30.119 30.158 42.338 1.00 40.83 C ATOM 2923 N1 DC C 21 29.636 30.179 43.760 1.00 36.77 N ATOM 2924 C2 DC C 21 29.535 28.984 44.522 1.00 36.43 C ATOM 2925 O2 DC C 21 29.846 27.877 44.083 1.00 34.96 O ATOM 2926 N3 DC C 21 29.107 29.078 45.806 1.00 36.09 N ATOM 2927 C4 DC C 21 28.784 30.261 46.339 1.00 34.98 C ATOM 2928 N4 DC C 21 28.368 30.282 47.612 1.00 37.76 N ATOM 2929 C5 DC C 21 28.846 31.475 45.593 1.00 36.04 C ATOM 2930 C6 DC C 21 29.286 31.372 44.330 1.00 36.44 C ATOM 2931 P DA C 22 29.305 30.036 37.869 1.00 41.31 P ATOM 2932 OP1 DA C 22 30.140 29.779 36.649 1.00 42.16 O ATOM 2933 OP2 DA C 22 28.293 31.124 37.939 1.00 36.36 O ATOM 2934 O5' DA C 22 28.496 28.670 38.213 1.00 31.49 O ATOM 2935 C5' DA C 22 29.215 27.504 38.185 1.00 25.62 C ATOM 2936 C4' DA C 22 28.291 26.430 38.773 1.00 24.63 C ATOM 2937 O4' DA C 22 28.054 26.680 40.193 1.00 23.26 O ATOM 2938 C3' DA C 22 26.884 26.423 38.147 1.00 16.68 C ATOM 2939 O3' DA C 22 26.605 25.016 38.078 1.00 15.48 O ATOM 2940 C2' DA C 22 25.961 27.092 39.140 1.00 22.63 C ATOM 2941 C1' DA C 22 26.659 26.626 40.429 1.00 20.16 C ATOM 2942 N9 DA C 22 26.399 27.511 41.546 1.00 21.62 N ATOM 2943 C8 DA C 22 26.287 28.862 41.509 1.00 22.42 C ATOM 2944 N7 DA C 22 26.090 29.398 42.713 1.00 27.52 N ATOM 2945 C5 DA C 22 26.061 28.291 43.568 1.00 23.57 C ATOM 2946 C6 DA C 22 25.874 28.163 44.964 1.00 22.82 C ATOM 2947 N6 DA C 22 25.699 29.223 45.774 1.00 26.96 N ATOM 2948 N1 DA C 22 25.943 26.911 45.473 1.00 23.62 N ATOM 2949 C2 DA C 22 26.152 25.819 44.706 1.00 23.83 C ATOM 2950 N3 DA C 22 26.284 25.823 43.369 1.00 18.83 N ATOM 2951 C4 DA C 22 26.255 27.116 42.877 1.00 22.00 C HETATM 2952 P 8OG C 23 26.536 24.036 36.792 1.00 15.99 P HETATM 2953 OP1 8OG C 23 26.494 22.586 37.088 1.00 16.76 O HETATM 2954 OP2 8OG C 23 27.703 24.480 35.842 1.00 17.08 O HETATM 2955 O5' 8OG C 23 25.156 24.521 36.075 1.00 16.43 O HETATM 2956 C5' 8OG C 23 23.900 24.285 36.735 1.00 14.72 C HETATM 2957 C4' 8OG C 23 22.954 25.451 36.410 1.00 13.42 C HETATM 2958 O4' 8OG C 23 22.468 25.208 35.077 1.00 13.23 O HETATM 2959 C3' 8OG C 23 21.693 25.401 37.303 1.00 13.25 C HETATM 2960 O3' 8OG C 23 21.030 26.668 37.139 1.00 14.29 O HETATM 2961 C2' 8OG C 23 20.845 24.376 36.582 1.00 13.35 C HETATM 2962 C1' 8OG C 23 21.092 24.784 35.111 1.00 14.64 C HETATM 2963 N9 8OG C 23 20.923 23.726 34.131 1.00 14.10 N HETATM 2964 C8 8OG C 23 20.853 22.376 34.150 1.00 15.05 C HETATM 2965 N7 8OG C 23 20.596 21.779 32.972 1.00 12.73 N HETATM 2966 C5 8OG C 23 20.533 22.900 32.084 1.00 10.57 C HETATM 2967 C6 8OG C 23 20.316 22.966 30.702 1.00 13.93 C HETATM 2968 O6 8OG C 23 20.160 21.984 29.999 1.00 13.62 O HETATM 2969 N1 8OG C 23 20.246 24.234 30.166 1.00 11.31 N HETATM 2970 C2 8OG C 23 20.439 25.312 30.965 1.00 10.84 C HETATM 2971 N2 8OG C 23 20.506 26.570 30.319 1.00 12.54 N HETATM 2972 N3 8OG C 23 20.691 25.302 32.304 1.00 13.72 N HETATM 2973 C4 8OG C 23 20.736 24.032 32.826 1.00 11.46 C HETATM 2974 O8 8OG C 23 21.045 21.698 35.264 1.00 15.88 O ATOM 2975 P DG C 24 21.540 28.006 37.865 1.00 15.93 P ATOM 2976 OP1 DG C 24 22.013 28.940 36.716 1.00 17.43 O ATOM 2977 OP2 DG C 24 22.469 27.757 38.944 1.00 16.74 O ATOM 2978 O5' DG C 24 20.234 28.696 38.432 1.00 16.03 O ATOM 2979 C5' DG C 24 19.273 29.320 37.570 1.00 15.24 C ATOM 2980 C4' DG C 24 17.900 29.282 38.250 1.00 14.85 C ATOM 2981 O4' DG C 24 18.030 29.667 39.654 1.00 19.55 O ATOM 2982 C3' DG C 24 16.854 30.179 37.657 1.00 17.11 C ATOM 2983 O3' DG C 24 15.593 29.550 37.861 1.00 19.10 O ATOM 2984 C2' DG C 24 16.996 31.469 38.494 1.00 16.93 C ATOM 2985 C1' DG C 24 17.450 30.993 39.854 1.00 19.78 C ATOM 2986 N9 DG C 24 18.516 31.762 40.447 1.00 23.58 N ATOM 2987 C8 DG C 24 19.613 32.362 39.792 1.00 19.48 C ATOM 2988 N7 DG C 24 20.460 32.944 40.560 1.00 21.45 N ATOM 2989 C5 DG C 24 19.902 32.757 41.853 1.00 25.23 C ATOM 2990 C6 DG C 24 20.383 33.188 43.109 1.00 24.53 C ATOM 2991 O6 DG C 24 21.374 33.870 43.392 1.00 24.67 O ATOM 2992 N1 DG C 24 19.514 32.751 44.151 1.00 23.35 N ATOM 2993 C2 DG C 24 18.361 32.051 43.911 1.00 20.26 C ATOM 2994 N2 DG C 24 17.649 31.736 45.034 1.00 21.70 N ATOM 2995 N3 DG C 24 17.851 31.597 42.764 1.00 21.96 N ATOM 2996 C4 DG C 24 18.718 32.044 41.774 1.00 22.40 C ATOM 2997 P DT C 25 14.127 30.164 37.704 1.00 19.73 P ATOM 2998 OP1 DT C 25 13.193 29.214 37.179 1.00 18.29 O ATOM 2999 OP2 DT C 25 14.251 31.501 36.947 1.00 21.53 O ATOM 3000 O5' DT C 25 13.750 30.560 39.175 1.00 21.51 O ATOM 3001 C5' DT C 25 13.693 29.416 40.139 1.00 20.25 C ATOM 3002 C4' DT C 25 13.182 30.007 41.469 1.00 21.06 C ATOM 3003 O4' DT C 25 14.151 30.871 42.125 1.00 23.73 O ATOM 3004 C3' DT C 25 11.882 30.801 41.277 1.00 27.22 C ATOM 3005 O3' DT C 25 11.045 30.346 42.374 1.00 26.81 O ATOM 3006 C2' DT C 25 12.338 32.267 41.422 1.00 27.49 C ATOM 3007 C1' DT C 25 13.475 32.173 42.405 1.00 23.27 C ATOM 3008 N1 DT C 25 14.628 33.141 42.341 1.00 26.26 N ATOM 3009 C2 DT C 25 15.213 33.644 43.504 1.00 24.45 C ATOM 3010 O2 DT C 25 14.776 33.306 44.611 1.00 27.13 O ATOM 3011 N3 DT C 25 16.347 34.486 43.438 1.00 23.96 N ATOM 3012 C4 DT C 25 16.878 34.883 42.187 1.00 25.27 C ATOM 3013 O4 DT C 25 17.871 35.599 42.179 1.00 26.63 O ATOM 3014 C5 DT C 25 16.200 34.360 41.016 1.00 23.36 C ATOM 3015 C7 DT C 25 16.733 34.768 39.628 1.00 23.50 C ATOM 3016 C6 DT C 25 15.150 33.527 41.089 1.00 24.78 C ATOM 3017 P DC C 26 9.594 31.035 42.689 1.00 26.67 P ATOM 3018 OP1 DC C 26 8.750 29.939 43.280 1.00 28.52 O ATOM 3019 OP2 DC C 26 9.084 31.730 41.514 1.00 26.32 O ATOM 3020 O5' DC C 26 10.091 31.999 43.804 1.00 28.20 O ATOM 3021 C5' DC C 26 10.676 31.497 45.002 1.00 35.97 C ATOM 3022 C4' DC C 26 10.771 32.565 46.058 1.00 40.73 C ATOM 3023 O4' DC C 26 11.872 33.459 45.747 1.00 41.89 O ATOM 3024 C3' DC C 26 9.532 33.443 46.271 1.00 43.40 C ATOM 3025 O3' DC C 26 9.360 33.504 47.702 1.00 49.72 O ATOM 3026 C2' DC C 26 9.891 34.788 45.655 1.00 39.86 C ATOM 3027 C1' DC C 26 11.403 34.802 45.838 1.00 40.77 C ATOM 3028 N1 DC C 26 12.220 35.520 44.808 1.00 38.05 N ATOM 3029 C2 DC C 26 13.327 36.268 45.233 1.00 36.39 C ATOM 3030 O2 DC C 26 13.676 36.383 46.423 1.00 32.65 O ATOM 3031 N3 DC C 26 14.063 36.875 44.290 1.00 36.13 N ATOM 3032 C4 DC C 26 13.780 36.774 42.999 1.00 35.46 C ATOM 3033 N4 DC C 26 14.624 37.465 42.225 1.00 34.19 N ATOM 3034 C5 DC C 26 12.650 36.042 42.524 1.00 31.77 C ATOM 3035 C6 DC C 26 11.916 35.410 43.463 1.00 38.60 C ATOM 3036 P DT C 27 8.068 34.111 48.499 1.00 50.80 P ATOM 3037 OP1 DT C 27 7.892 33.238 49.697 1.00 47.88 O ATOM 3038 OP2 DT C 27 6.984 34.498 47.539 1.00 47.26 O ATOM 3039 O5' DT C 27 8.678 35.510 48.999 1.00 50.11 O ATOM 3040 C5' DT C 27 9.817 35.563 49.856 1.00 49.33 C ATOM 3041 C4' DT C 27 10.267 37.017 49.960 1.00 50.21 C ATOM 3042 O4' DT C 27 11.043 37.411 48.805 1.00 49.86 O ATOM 3043 C3' DT C 27 9.141 38.049 50.048 1.00 51.22 C ATOM 3044 O3' DT C 27 9.460 38.824 51.175 1.00 54.15 O ATOM 3045 C2' DT C 27 9.243 38.872 48.763 1.00 49.19 C ATOM 3046 C1' DT C 27 10.728 38.733 48.439 1.00 48.84 C ATOM 3047 N1 DT C 27 11.027 38.978 46.998 1.00 45.48 N ATOM 3048 C2 DT C 27 12.138 39.722 46.636 1.00 44.00 C ATOM 3049 O2 DT C 27 12.950 40.186 47.419 1.00 43.18 O ATOM 3050 N3 DT C 27 12.293 39.882 45.281 1.00 43.42 N ATOM 3051 C4 DT C 27 11.461 39.418 44.272 1.00 43.01 C ATOM 3052 O4 DT C 27 11.711 39.618 43.083 1.00 43.90 O ATOM 3053 C5 DT C 27 10.309 38.660 44.719 1.00 43.90 C ATOM 3054 C7 DT C 27 9.347 38.083 43.715 1.00 44.16 C ATOM 3055 C6 DT C 27 10.146 38.487 46.041 1.00 44.74 C ATOM 3056 P DA C 28 8.515 39.951 51.843 1.00 55.33 P ATOM 3057 OP1 DA C 28 8.509 39.601 53.292 1.00 56.05 O ATOM 3058 OP2 DA C 28 7.275 40.154 51.037 1.00 52.98 O ATOM 3059 O5' DA C 28 9.404 41.263 51.642 1.00 56.06 O ATOM 3060 C5' DA C 28 10.730 41.334 52.186 1.00 58.52 C ATOM 3061 C4' DA C 28 11.370 42.583 51.612 1.00 61.52 C ATOM 3062 O4' DA C 28 11.552 42.411 50.178 1.00 59.10 O ATOM 3063 C3' DA C 28 10.498 43.833 51.770 1.00 63.99 C ATOM 3064 O3' DA C 28 11.313 44.948 52.121 1.00 70.05 O ATOM 3065 C2' DA C 28 9.857 44.027 50.394 1.00 62.04 C ATOM 3066 C1' DA C 28 10.993 43.512 49.500 1.00 59.30 C ATOM 3067 N9 DA C 28 10.625 43.161 48.122 1.00 55.55 N ATOM 3068 C8 DA C 28 9.521 42.478 47.679 1.00 55.47 C ATOM 3069 N7 DA C 28 9.462 42.342 46.375 1.00 53.29 N ATOM 3070 C5 DA C 28 10.609 42.979 45.944 1.00 51.75 C ATOM 3071 C6 DA C 28 11.132 43.187 44.662 1.00 50.53 C ATOM 3072 N6 DA C 28 10.518 42.725 43.572 1.00 49.52 N ATOM 3073 N1 DA C 28 12.305 43.873 44.552 1.00 50.80 N ATOM 3074 C2 DA C 28 12.914 44.334 45.659 1.00 49.46 C ATOM 3075 N3 DA C 28 12.509 44.192 46.919 1.00 51.91 N ATOM 3076 C4 DA C 28 11.338 43.503 46.992 1.00 52.59 C ATOM 3077 P DC C 29 10.720 46.262 52.842 1.00 72.96 P ATOM 3078 OP1 DC C 29 11.691 46.546 53.938 1.00 70.58 O ATOM 3079 OP2 DC C 29 9.281 45.992 53.154 1.00 71.75 O ATOM 3080 O5' DC C 29 10.811 47.394 51.679 1.00 73.15 O ATOM 3081 C5' DC C 29 10.820 48.824 51.952 1.00 76.26 C ATOM 3082 C4' DC C 29 11.742 49.630 51.024 1.00 77.20 C ATOM 3083 O4' DC C 29 12.157 48.759 49.935 1.00 77.39 O ATOM 3084 C3' DC C 29 11.159 50.918 50.401 1.00 77.41 C ATOM 3085 O3' DC C 29 12.105 51.994 50.336 1.00 75.69 O ATOM 3086 C2' DC C 29 10.770 50.494 48.988 1.00 77.42 C ATOM 3087 C1' DC C 29 11.645 49.252 48.708 1.00 77.31 C ATOM 3088 N1 DC C 29 10.926 48.190 47.848 1.00 75.83 N ATOM 3089 C2 DC C 29 11.395 47.958 46.524 1.00 74.78 C ATOM 3090 O2 DC C 29 12.393 48.576 46.096 1.00 73.62 O ATOM 3091 N3 DC C 29 10.743 47.053 45.736 1.00 72.09 N ATOM 3092 C4 DC C 29 9.679 46.391 46.204 1.00 72.63 C ATOM 3093 N4 DC C 29 9.092 45.513 45.373 1.00 70.81 N ATOM 3094 C5 DC C 29 9.183 46.611 47.541 1.00 73.55 C ATOM 3095 C6 DC C 29 9.821 47.513 48.320 1.00 74.83 C TER 3096 DC C 29 HETATM 3097 CA CA A1327 6.697 30.214 40.532 1.00 58.01 CA2+ HETATM 3098 CA CA C1030 23.624 29.963 40.236 1.00 48.34 CA2+ HETATM 3099 O HOH A2001 23.283 -8.477 38.321 1.00 19.79 O HETATM 3100 O HOH A2002 23.181 -13.115 33.975 1.00 36.65 O HETATM 3101 O HOH A2003 27.801 -13.504 39.589 1.00 37.78 O HETATM 3102 O HOH A2004 25.660 -8.967 35.389 1.00 31.69 O HETATM 3103 O HOH A2005 20.712 -8.640 37.672 1.00 32.67 O HETATM 3104 O HOH A2006 24.435 -14.082 31.896 1.00 47.09 O HETATM 3105 O HOH A2007 25.259 -13.725 29.085 1.00 36.53 O HETATM 3106 O HOH A2008 28.190 -1.436 33.695 1.00 22.24 O HETATM 3107 O HOH A2009 23.161 -10.175 34.601 1.00 27.19 O HETATM 3108 O HOH A2010 25.778 12.911 7.499 1.00 37.73 O HETATM 3109 O HOH A2011 33.747 -9.226 32.382 1.00 51.67 O HETATM 3110 O HOH A2012 29.613 -8.760 23.596 1.00 41.90 O HETATM 3111 O HOH A2013 32.209 -4.688 27.525 1.00 38.90 O HETATM 3112 O HOH A2014 18.062 -2.798 13.967 1.00 52.74 O HETATM 3113 O HOH A2015 14.488 -0.627 17.888 1.00 45.59 O HETATM 3114 O HOH A2016 14.235 -3.988 17.360 1.00 34.83 O HETATM 3115 O HOH A2017 26.249 16.003 12.694 1.00 41.42 O HETATM 3116 O HOH A2018 27.976 15.481 13.731 1.00 36.22 O HETATM 3117 O HOH A2019 7.728 2.199 28.165 1.00 49.79 O HETATM 3118 O HOH A2020 25.962 -8.256 22.164 1.00 46.83 O HETATM 3119 O HOH A2021 21.842 8.420 10.879 1.00 41.36 O HETATM 3120 O HOH A2022 22.775 11.682 8.567 1.00 43.80 O HETATM 3121 O HOH A2023 20.334 2.146 9.938 1.00 44.45 O HETATM 3122 O HOH A2024 30.861 12.178 33.112 1.00 29.31 O HETATM 3123 O HOH A2025 29.283 13.118 35.509 1.00 39.20 O HETATM 3124 O HOH A2026 29.355 19.024 34.967 1.00 39.88 O HETATM 3125 O HOH A2027 19.466 -6.647 18.482 1.00 39.11 O HETATM 3126 O HOH A2028 16.761 -2.418 17.018 1.00 28.80 O HETATM 3127 O HOH A2029 19.872 6.161 40.483 1.00 30.86 O HETATM 3128 O HOH A2030 19.811 6.990 14.861 1.00 36.17 O HETATM 3129 O HOH A2031 34.798 2.984 36.836 1.00 47.15 O HETATM 3130 O HOH A2032 26.589 4.708 18.603 1.00 18.15 O HETATM 3131 O HOH A2033 25.627 15.552 15.649 1.00 21.97 O HETATM 3132 O HOH A2034 9.674 -0.247 28.666 1.00 33.73 O HETATM 3133 O HOH A2035 10.408 7.378 29.205 1.00 28.11 O HETATM 3134 O HOH A2036 9.333 7.313 33.139 1.00 46.91 O HETATM 3135 O HOH A2037 9.657 -3.056 39.689 1.00 40.52 O HETATM 3136 O HOH A2038 7.371 1.129 39.808 1.00 32.51 O HETATM 3137 O HOH A2039 23.022 10.794 11.278 1.00 35.13 O HETATM 3138 O HOH A2040 34.867 15.103 22.508 1.00 43.01 O HETATM 3139 O HOH A2041 21.773 4.041 11.499 1.00 32.57 O HETATM 3140 O HOH A2042 31.103 11.900 30.280 1.00 30.44 O HETATM 3141 O HOH A2043 21.765 14.540 31.213 1.00 12.47 O HETATM 3142 O HOH A2044 22.860 11.735 34.910 1.00 14.09 O HETATM 3143 O HOH A2045 27.406 14.894 35.789 1.00 27.99 O HETATM 3144 O HOH A2046 28.796 17.357 33.542 1.00 40.87 O HETATM 3145 O HOH A2047 21.947 19.915 29.329 1.00 13.74 O HETATM 3146 O HOH A2048 9.695 -2.982 17.289 1.00 45.71 O HETATM 3147 O HOH A2049 7.170 3.098 24.141 1.00 41.75 O HETATM 3148 O HOH A2050 8.006 4.411 26.579 1.00 35.32 O HETATM 3149 O HOH A2051 23.184 15.278 34.318 1.00 12.65 O HETATM 3150 O HOH A2052 16.489 13.724 36.191 1.00 16.71 O HETATM 3151 O HOH A2053 21.976 6.084 38.106 1.00 23.28 O HETATM 3152 O HOH A2054 18.530 6.051 37.908 1.00 23.12 O HETATM 3153 O HOH A2055 18.864 8.869 40.510 1.00 26.05 O HETATM 3154 O HOH A2056 8.885 17.525 19.486 1.00 32.43 O HETATM 3155 O HOH A2057 10.659 11.866 17.430 1.00 40.01 O HETATM 3156 O HOH A2058 24.792 37.287 37.049 1.00 39.27 O HETATM 3157 O HOH A2059 26.809 10.937 35.585 1.00 25.69 O HETATM 3158 O HOH A2060 26.927 19.599 10.624 1.00 45.49 O HETATM 3159 O HOH A2061 28.230 13.727 39.749 1.00 35.97 O HETATM 3160 O HOH A2062 29.206 9.215 38.574 1.00 33.32 O HETATM 3161 O HOH A2063 32.502 9.833 30.321 1.00 33.46 O HETATM 3162 O HOH A2064 31.069 9.676 34.272 1.00 21.79 O HETATM 3163 O HOH A2065 34.330 9.309 31.927 1.00 38.90 O HETATM 3164 O HOH A2066 31.058 5.412 38.703 1.00 44.55 O HETATM 3165 O HOH A2067 33.205 4.087 35.204 1.00 31.88 O HETATM 3166 O HOH A2068 28.855 9.052 35.888 1.00 19.54 O HETATM 3167 O HOH A2069 32.553 7.393 28.374 1.00 34.03 O HETATM 3168 O HOH A2070 27.050 31.792 8.474 1.00 31.46 O HETATM 3169 O HOH A2071 28.756 -0.363 40.868 1.00 32.45 O HETATM 3170 O HOH A2072 31.523 2.513 39.530 1.00 43.01 O HETATM 3171 O HOH A2073 26.586 5.137 42.490 1.00 38.80 O HETATM 3172 O HOH A2074 23.763 4.518 39.256 1.00 28.37 O HETATM 3173 O HOH A2075 35.143 33.485 17.962 0.50 15.28 O HETATM 3174 O HOH A2076 33.084 -1.325 31.177 1.00 38.00 O HETATM 3175 O HOH A2077 29.401 4.195 25.348 1.00 21.18 O HETATM 3176 O HOH A2078 30.355 6.789 27.233 1.00 21.94 O HETATM 3177 O HOH A2079 26.977 1.018 34.109 1.00 15.75 O HETATM 3178 O HOH A2080 8.293 6.975 30.602 1.00 41.24 O HETATM 3179 O HOH A2081 14.711 8.508 33.396 1.00 33.11 O HETATM 3180 O HOH A2082 11.663 0.226 30.529 1.00 29.21 O HETATM 3181 O HOH A2083 11.849 7.625 31.681 1.00 35.36 O HETATM 3182 O HOH A2084 8.855 3.352 39.286 1.00 28.94 O HETATM 3183 O HOH A2085 5.955 5.968 38.297 1.00 42.27 O HETATM 3184 O HOH A2086 11.168 5.994 34.574 1.00 32.99 O HETATM 3185 O HOH A2087 11.740 -2.721 37.799 1.00 45.31 O HETATM 3186 O HOH A2088 10.606 -4.526 35.748 1.00 33.66 O HETATM 3187 O HOH A2089 28.395 17.768 45.695 1.00 43.27 O HETATM 3188 O HOH A2090 29.548 17.278 37.807 1.00 38.53 O HETATM 3189 O HOH A2091 26.212 17.221 47.518 1.00 35.48 O HETATM 3190 O HOH A2092 20.331 9.724 51.902 1.00 42.14 O HETATM 3191 O HOH A2093 31.304 -0.418 25.004 1.00 41.49 O HETATM 3192 O HOH A2094 5.893 8.022 51.293 1.00 32.65 O HETATM 3193 O HOH A2095 5.743 5.702 42.521 1.00 42.31 O HETATM 3194 O HOH A2096 11.609 1.978 49.531 1.00 33.01 O HETATM 3195 O HOH A2097 29.519 7.127 24.568 1.00 29.73 O HETATM 3196 O HOH A2098 31.690 4.613 20.662 1.00 46.16 O HETATM 3197 O HOH A2099 7.105 1.684 47.170 1.00 45.86 O HETATM 3198 O HOH A2100 6.514 -0.763 44.181 1.00 46.14 O HETATM 3199 O HOH A2101 7.812 -0.616 41.401 1.00 45.94 O HETATM 3200 O HOH A2102 29.242 -0.474 15.623 1.00 49.39 O HETATM 3201 O HOH A2103 30.455 4.280 45.821 1.00 46.47 O HETATM 3202 O HOH A2104 17.290 -0.928 49.877 1.00 45.28 O HETATM 3203 O HOH A2105 23.880 2.938 12.437 1.00 31.37 O HETATM 3204 O HOH A2106 21.063 -2.984 15.256 1.00 40.20 O HETATM 3205 O HOH A2107 2.336 7.523 48.830 1.00 48.98 O HETATM 3206 O HOH A2108 23.656 -5.888 21.243 1.00 28.20 O HETATM 3207 O HOH A2109 9.419 11.745 57.440 1.00 46.73 O HETATM 3208 O HOH A2110 17.144 -9.232 31.959 1.00 28.01 O HETATM 3209 O HOH A2111 14.174 -2.544 36.929 1.00 26.21 O HETATM 3210 O HOH A2112 10.592 -8.208 38.653 1.00 61.66 O HETATM 3211 O HOH A2113 16.150 -9.344 34.441 1.00 30.51 O HETATM 3212 O HOH A2114 11.382 31.913 50.572 1.00 47.05 O HETATM 3213 O HOH A2115 16.440 -8.022 37.317 1.00 38.48 O HETATM 3214 O HOH A2116 17.213 -10.582 36.458 1.00 49.45 O HETATM 3215 O HOH A2117 13.671 -10.515 33.190 1.00 33.30 O HETATM 3216 O HOH A2118 13.048 -13.467 30.438 1.00 45.51 O HETATM 3217 O HOH A2119 18.556 -15.143 34.855 1.00 43.19 O HETATM 3218 O HOH A2120 18.424 -7.264 28.866 1.00 21.92 O HETATM 3219 O HOH A2121 13.618 -10.940 25.140 1.00 40.78 O HETATM 3220 O HOH A2122 17.417 -13.217 25.656 1.00 43.26 O HETATM 3221 O HOH A2123 11.405 34.535 29.510 1.00 46.83 O HETATM 3222 O HOH A2124 7.399 33.027 26.758 1.00 43.39 O HETATM 3223 O HOH A2125 15.369 -7.924 21.151 1.00 40.59 O HETATM 3224 O HOH A2126 -1.729 30.150 33.645 1.00 44.27 O HETATM 3225 O HOH A2127 7.818 -6.131 26.286 1.00 39.46 O HETATM 3226 O HOH A2128 4.134 33.741 32.935 1.00 44.88 O HETATM 3227 O HOH A2129 11.931 -2.018 18.568 1.00 36.13 O HETATM 3228 O HOH A2130 7.893 -2.515 18.885 1.00 56.65 O HETATM 3229 O HOH A2131 7.462 0.468 23.474 1.00 34.76 O HETATM 3230 O HOH A2132 7.993 -6.611 21.898 1.00 39.98 O HETATM 3231 O HOH A2133 1.493 27.705 46.023 1.00 42.02 O HETATM 3232 O HOH A2134 9.069 -4.578 30.156 1.00 40.13 O HETATM 3233 O HOH A2135 10.339 5.888 26.850 1.00 25.25 O HETATM 3234 O HOH A2136 9.903 10.312 21.531 1.00 33.57 O HETATM 3235 O HOH A2137 9.759 8.927 26.077 1.00 41.11 O HETATM 3236 O HOH A2138 15.166 11.166 32.689 1.00 25.67 O HETATM 3237 O HOH A2139 19.979 33.045 36.637 1.00 22.65 O HETATM 3238 O HOH A2140 10.249 16.979 22.039 1.00 20.81 O HETATM 3239 O HOH A2141 26.660 36.782 35.298 1.00 40.17 O HETATM 3240 O HOH A2142 26.795 35.550 38.864 1.00 48.29 O HETATM 3241 O HOH A2143 18.384 9.553 14.814 1.00 28.96 O HETATM 3242 O HOH A2144 26.008 39.735 33.714 1.00 42.15 O HETATM 3243 O HOH A2145 8.488 10.600 16.133 1.00 44.02 O HETATM 3244 O HOH A2146 11.541 9.780 18.278 1.00 26.36 O HETATM 3245 O HOH A2147 15.831 10.445 12.930 1.00 39.84 O HETATM 3246 O HOH A2148 29.727 42.801 27.208 1.00 56.41 O HETATM 3247 O HOH A2149 17.493 9.718 11.848 1.00 35.16 O HETATM 3248 O HOH A2150 25.391 17.383 10.048 1.00 25.27 O HETATM 3249 O HOH A2151 18.816 12.555 6.717 1.00 26.85 O HETATM 3250 O HOH A2152 10.112 42.084 29.347 1.00 45.42 O HETATM 3251 O HOH A2153 20.048 35.620 37.638 1.00 37.83 O HETATM 3252 O HOH A2154 27.063 22.312 12.043 1.00 33.36 O HETATM 3253 O HOH A2155 21.067 23.291 3.263 1.00 44.18 O HETATM 3254 O HOH A2156 26.176 23.565 8.278 1.00 28.26 O HETATM 3255 O HOH A2157 12.106 34.316 16.051 1.00 35.73 O HETATM 3256 O HOH A2158 17.180 29.787 11.630 1.00 36.74 O HETATM 3257 O HOH A2159 19.591 25.404 6.744 1.00 40.13 O HETATM 3258 O HOH A2160 10.216 29.552 17.574 1.00 33.48 O HETATM 3259 O HOH A2161 8.733 22.858 14.799 1.00 35.48 O HETATM 3260 O HOH A2162 8.196 27.079 16.625 1.00 36.10 O HETATM 3261 O HOH A2163 27.916 29.150 8.414 1.00 30.72 O HETATM 3262 O HOH A2164 22.138 25.390 4.344 1.00 43.89 O HETATM 3263 O HOH A2165 25.223 24.859 3.980 1.00 49.88 O HETATM 3264 O HOH A2166 23.001 29.820 5.261 1.00 42.33 O HETATM 3265 O HOH A2167 31.626 31.463 8.279 1.00 34.46 O HETATM 3266 O HOH A2168 29.375 28.563 22.585 1.00 19.63 O HETATM 3267 O HOH A2169 33.255 28.014 22.117 1.00 40.60 O HETATM 3268 O HOH A2170 32.398 28.169 11.030 1.00 29.73 O HETATM 3269 O HOH A2171 33.275 31.409 16.346 1.00 27.23 O HETATM 3270 O HOH A2172 35.470 28.652 16.392 1.00 40.01 O HETATM 3271 O HOH A2173 29.604 13.956 13.712 1.00 43.66 O HETATM 3272 O HOH A2174 20.250 18.939 20.636 1.00 23.79 O HETATM 3273 O HOH A2175 15.996 16.333 28.045 1.00 14.81 O HETATM 3274 O HOH A2176 12.444 16.811 24.907 1.00 16.38 O HETATM 3275 O HOH A2177 7.650 8.669 24.624 1.00 51.06 O HETATM 3276 O HOH A2178 9.923 9.825 28.083 1.00 28.96 O HETATM 3277 O HOH A2179 15.505 15.982 34.598 1.00 23.16 O HETATM 3278 O HOH A2180 14.946 12.631 33.994 1.00 29.02 O HETATM 3279 O HOH A2181 12.151 10.638 32.443 1.00 20.82 O HETATM 3280 O HOH A2182 4.671 12.061 34.409 1.00 40.98 O HETATM 3281 O HOH A2183 8.181 10.653 37.226 1.00 42.64 O HETATM 3282 O HOH A2184 6.086 9.794 30.900 1.00 38.19 O HETATM 3283 O HOH A2185 13.125 7.450 36.197 1.00 24.29 O HETATM 3284 O HOH A2186 9.750 9.165 35.970 1.00 31.92 O HETATM 3285 O HOH A2187 14.776 17.108 43.293 1.00 22.16 O HETATM 3286 O HOH A2188 17.425 25.816 37.454 1.00 18.10 O HETATM 3287 O HOH A2189 16.908 28.870 43.690 1.00 22.10 O HETATM 3288 O HOH A2190 24.365 32.328 42.878 1.00 39.09 O HETATM 3289 O HOH A2191 29.064 19.952 44.322 1.00 26.30 O HETATM 3290 O HOH A2192 27.079 13.663 42.468 1.00 31.75 O HETATM 3291 O HOH A2193 28.129 15.578 38.115 1.00 32.85 O HETATM 3292 O HOH A2194 28.947 19.872 39.116 1.00 23.68 O HETATM 3293 O HOH A2195 24.058 16.070 46.713 1.00 23.63 O HETATM 3294 O HOH A2196 20.469 11.426 40.635 1.00 27.88 O HETATM 3295 O HOH A2197 24.265 13.904 36.534 1.00 15.93 O HETATM 3296 O HOH A2198 22.906 5.786 41.448 1.00 35.49 O HETATM 3297 O HOH A2199 23.402 9.899 38.697 1.00 36.20 O HETATM 3298 O HOH A2200 17.800 6.373 44.396 1.00 26.87 O HETATM 3299 O HOH A2201 21.786 8.842 38.982 1.00 31.71 O HETATM 3300 O HOH A2202 17.328 8.924 50.783 1.00 23.89 O HETATM 3301 O HOH A2203 23.900 10.906 47.898 1.00 28.31 O HETATM 3302 O HOH A2204 20.660 3.166 48.408 1.00 42.14 O HETATM 3303 O HOH A2205 19.070 8.287 50.740 1.00 51.54 O HETATM 3304 O HOH A2206 20.327 7.617 47.952 1.00 42.28 O HETATM 3305 O HOH A2207 21.244 4.186 52.929 1.00 59.69 O HETATM 3306 O HOH A2208 9.072 4.892 50.104 1.00 43.62 O HETATM 3307 O HOH A2209 9.676 8.139 52.932 1.00 48.85 O HETATM 3308 O HOH A2210 11.691 6.946 53.524 1.00 51.18 O HETATM 3309 O HOH A2211 6.476 7.073 45.012 1.00 22.93 O HETATM 3310 O HOH A2212 7.029 6.958 49.333 1.00 37.45 O HETATM 3311 O HOH A2213 11.571 4.559 48.921 1.00 31.10 O HETATM 3312 O HOH A2214 7.224 3.988 46.963 1.00 48.14 O HETATM 3313 O HOH A2215 9.869 0.434 47.658 1.00 30.92 O HETATM 3314 O HOH A2216 8.868 -1.483 43.283 1.00 36.32 O HETATM 3315 O HOH A2217 11.785 -3.945 44.958 1.00 35.36 O HETATM 3316 O HOH A2218 13.780 -6.496 42.368 1.00 36.79 O HETATM 3317 O HOH A2219 17.001 -6.595 43.029 1.00 37.78 O HETATM 3318 O HOH A2220 29.603 -4.398 38.281 1.00 43.70 O HETATM 3319 O HOH A2221 28.198 2.582 44.847 1.00 38.62 O HETATM 3320 O HOH A2222 29.521 -0.052 43.334 1.00 39.71 O HETATM 3321 O HOH A2223 24.724 2.668 47.176 1.00 34.28 O HETATM 3322 O HOH A2224 30.941 1.069 46.071 1.00 39.91 O HETATM 3323 O HOH A2225 21.977 0.089 48.010 1.00 27.27 O HETATM 3324 O HOH A2226 19.276 4.719 45.906 1.00 37.73 O HETATM 3325 O HOH A2227 22.142 3.074 46.279 1.00 25.35 O HETATM 3326 O HOH A2228 18.427 -2.949 47.969 1.00 20.78 O HETATM 3327 O HOH A2229 20.581 4.902 42.634 1.00 36.11 O HETATM 3328 O HOH A2230 17.578 5.493 41.752 1.00 22.48 O HETATM 3329 O HOH A2231 17.627 1.894 48.872 1.00 29.54 O HETATM 3330 O HOH A2232 7.630 5.747 40.314 1.00 33.63 O HETATM 3331 O HOH A2233 10.357 6.279 37.501 1.00 29.91 O HETATM 3332 O HOH A2234 6.456 9.711 39.241 1.00 27.47 O HETATM 3333 O HOH A2235 2.588 6.647 45.453 1.00 34.01 O HETATM 3334 O HOH A2236 2.522 11.201 40.198 1.00 29.78 O HETATM 3335 O HOH A2237 1.398 10.812 50.844 1.00 34.35 O HETATM 3336 O HOH A2238 0.523 10.095 40.707 1.00 45.20 O HETATM 3337 O HOH A2239 -0.191 7.114 42.580 1.00 50.16 O HETATM 3338 O HOH A2240 5.069 10.707 51.446 1.00 27.93 O HETATM 3339 O HOH A2241 -0.257 15.433 52.340 0.50 20.59 O HETATM 3340 O HOH A2242 5.520 11.300 54.062 1.00 44.53 O HETATM 3341 O HOH A2243 10.261 13.999 58.412 1.00 39.32 O HETATM 3342 O HOH A2244 7.342 11.062 58.502 1.00 46.47 O HETATM 3343 O HOH A2245 10.353 21.619 57.162 1.00 44.84 O HETATM 3344 O HOH A2246 6.053 18.690 54.058 1.00 29.41 O HETATM 3345 O HOH A2247 14.269 18.681 58.857 1.00 31.36 O HETATM 3346 O HOH A2248 8.012 18.760 57.310 1.00 26.39 O HETATM 3347 O HOH A2249 16.919 8.902 54.910 1.00 39.71 O HETATM 3348 O HOH A2250 8.733 11.651 55.049 1.00 38.82 O HETATM 3349 O HOH A2251 17.110 23.154 54.803 1.00 33.49 O HETATM 3350 O HOH A2252 18.681 19.177 58.397 1.00 46.15 O HETATM 3351 O HOH A2253 14.279 23.845 58.440 1.00 56.01 O HETATM 3352 O HOH A2254 17.746 25.295 56.175 1.00 38.99 O HETATM 3353 O HOH A2255 20.767 15.031 58.068 1.00 30.61 O HETATM 3354 O HOH A2256 22.891 18.498 48.989 1.00 21.17 O HETATM 3355 O HOH A2257 11.919 27.660 50.562 1.00 32.66 O HETATM 3356 O HOH A2258 6.149 27.328 48.818 1.00 56.01 O HETATM 3357 O HOH A2259 12.946 29.882 49.735 1.00 36.29 O HETATM 3358 O HOH A2260 14.904 30.430 45.487 1.00 40.39 O HETATM 3359 O HOH A2261 4.656 17.250 51.100 1.00 26.18 O HETATM 3360 O HOH A2262 4.854 22.616 51.758 1.00 43.88 O HETATM 3361 O HOH A2263 1.233 24.432 47.750 1.00 32.80 O HETATM 3362 O HOH A2264 -7.595 21.302 48.254 1.00 34.20 O HETATM 3363 O HOH A2265 -2.923 22.645 48.451 1.00 42.00 O HETATM 3364 O HOH A2266 -1.487 24.058 47.351 1.00 36.59 O HETATM 3365 O HOH A2267 -4.955 24.329 37.049 1.00 55.06 O HETATM 3366 O HOH A2268 -3.091 13.104 39.922 1.00 34.35 O HETATM 3367 O HOH A2269 -4.105 11.719 36.225 1.00 44.62 O HETATM 3368 O HOH A2270 -3.037 26.052 33.979 1.00 32.45 O HETATM 3369 O HOH A2271 -5.627 21.089 32.896 1.00 42.12 O HETATM 3370 O HOH A2272 7.447 10.694 28.662 1.00 27.34 O HETATM 3371 O HOH A2273 -4.435 17.790 25.803 1.00 36.69 O HETATM 3372 O HOH A2274 -0.076 14.394 26.774 1.00 42.80 O HETATM 3373 O HOH A2275 0.705 21.933 20.501 1.00 30.79 O HETATM 3374 O HOH A2276 9.465 32.039 27.683 1.00 32.15 O HETATM 3375 O HOH A2277 4.159 25.662 20.839 1.00 37.19 O HETATM 3376 O HOH A2278 6.650 29.873 20.192 1.00 38.89 O HETATM 3377 O HOH A2279 8.212 31.245 21.154 1.00 39.18 O HETATM 3378 O HOH A2280 3.845 32.319 28.561 1.00 43.78 O HETATM 3379 O HOH A2281 -1.529 28.528 30.490 1.00 43.03 O HETATM 3380 O HOH A2282 5.315 32.975 31.042 1.00 36.09 O HETATM 3381 O HOH A2283 2.351 32.536 34.728 1.00 38.86 O HETATM 3382 O HOH A2284 2.949 32.597 37.977 1.00 51.09 O HETATM 3383 O HOH A2285 1.140 27.195 42.960 1.00 37.07 O HETATM 3384 O HOH A2286 13.760 25.843 42.295 1.00 19.80 O HETATM 3385 O HOH A2287 10.575 33.740 37.240 1.00 38.20 O HETATM 3386 O HOH A2288 11.204 32.076 28.106 1.00 25.33 O HETATM 3387 O HOH A2289 14.465 31.321 30.283 1.00 20.25 O HETATM 3388 O HOH A2290 9.714 16.696 25.612 1.00 17.93 O HETATM 3389 O HOH A2291 3.579 16.414 22.205 1.00 30.78 O HETATM 3390 O HOH A2292 3.455 22.165 21.686 1.00 33.32 O HETATM 3391 O HOH A2293 6.173 24.004 20.251 1.00 38.76 O HETATM 3392 O HOH A2294 13.187 31.083 26.271 1.00 18.24 O HETATM 3393 O HOH A2295 15.338 32.836 32.544 1.00 19.33 O HETATM 3394 O HOH A2296 17.799 32.145 35.074 1.00 19.78 O HETATM 3395 O HOH A2297 28.887 36.160 35.441 1.00 38.85 O HETATM 3396 O HOH A2298 30.776 36.830 29.635 1.00 36.60 O HETATM 3397 O HOH A2299 31.192 40.482 24.275 1.00 19.59 O HETATM 3398 O HOH A2300 27.365 37.680 33.023 1.00 48.99 O HETATM 3399 O HOH A2301 32.865 36.125 19.734 1.00 17.46 O HETATM 3400 O HOH A2302 31.370 27.585 26.229 1.00 29.50 O HETATM 3401 O HOH A2303 32.130 33.379 18.249 1.00 16.83 O HETATM 3402 O HOH A2304 34.015 33.139 20.444 1.00 23.86 O HETATM 3403 O HOH A2305 24.838 39.923 18.961 1.00 32.96 O HETATM 3404 O HOH A2306 25.804 38.757 17.675 0.50 36.30 O HETATM 3405 O HOH A2307 25.263 42.902 20.181 1.00 30.63 O HETATM 3406 O HOH A2308 30.924 37.711 18.718 1.00 14.05 O HETATM 3407 O HOH A2309 25.846 41.866 27.423 1.00 31.80 O HETATM 3408 O HOH A2310 18.605 40.755 21.100 1.00 34.61 O HETATM 3409 O HOH A2311 28.801 41.427 25.144 1.00 38.17 O HETATM 3410 O HOH A2312 27.416 47.859 25.227 1.00 50.88 O HETATM 3411 O HOH A2313 25.023 45.992 27.849 1.00 36.08 O HETATM 3412 O HOH A2314 23.159 46.740 27.179 1.00 44.25 O HETATM 3413 O HOH A2315 20.918 47.016 28.231 1.00 50.03 O HETATM 3414 O HOH A2316 25.297 44.014 28.927 1.00 35.71 O HETATM 3415 O HOH A2317 12.339 36.399 32.018 1.00 32.23 O HETATM 3416 O HOH A2318 15.491 37.521 36.820 1.00 48.78 O HETATM 3417 O HOH A2319 12.305 41.975 27.762 1.00 43.56 O HETATM 3418 O HOH A2320 13.199 43.429 34.215 1.00 31.97 O HETATM 3419 O HOH A2321 17.653 37.281 36.679 1.00 42.82 O HETATM 3420 O HOH A2322 14.329 33.471 28.430 1.00 21.16 O HETATM 3421 O HOH A2323 14.020 35.785 34.728 1.00 32.69 O HETATM 3422 O HOH A2324 9.625 33.780 26.592 1.00 28.54 O HETATM 3423 O HOH A2325 12.557 34.285 26.259 1.00 24.18 O HETATM 3424 O HOH A2326 15.749 39.542 21.227 1.00 30.71 O HETATM 3425 O HOH A2327 12.624 35.411 18.540 1.00 28.57 O HETATM 3426 O HOH A2328 12.932 40.444 22.616 1.00 40.58 O HETATM 3427 O HOH A2329 9.071 35.509 24.580 1.00 33.98 O HETATM 3428 O HOH A2330 10.659 34.268 20.229 1.00 27.28 O HETATM 3429 O HOH A2331 12.082 30.862 15.880 1.00 46.73 O HETATM 3430 O HOH A2332 15.086 31.697 12.503 1.00 42.31 O HETATM 3431 O HOH A2333 15.654 38.464 18.779 1.00 37.45 O HETATM 3432 O HOH A2334 19.616 36.281 16.388 1.00 28.33 O HETATM 3433 O HOH A2335 19.610 33.099 11.904 1.00 33.37 O HETATM 3434 O HOH A2336 15.805 25.096 14.535 1.00 16.65 O HETATM 3435 O HOH A2337 9.268 24.576 17.503 1.00 28.23 O HETATM 3436 O HOH A2338 10.301 16.978 17.356 1.00 32.77 O HETATM 3437 O HOH A2339 8.498 20.500 15.819 1.00 46.46 O HETATM 3438 O HOH A2340 11.792 19.398 22.520 1.00 17.32 O HETATM 3439 O HOH A2341 22.935 18.959 26.953 1.00 16.60 O HETATM 3440 O HOH A2342 29.568 26.547 24.390 1.00 19.80 O HETATM 3441 O HOH A2343 33.948 23.740 25.218 1.00 34.96 O HETATM 3442 O HOH A2344 30.058 29.551 31.835 1.00 31.91 O HETATM 3443 O HOH A2345 30.315 25.816 30.964 1.00 32.55 O HETATM 3444 O HOH A2346 31.240 14.248 29.464 1.00 42.98 O HETATM 3445 O HOH B2001 15.515 45.010 33.282 1.00 43.49 O HETATM 3446 O HOH B2002 19.064 48.542 35.444 1.00 41.29 O HETATM 3447 O HOH B2003 16.352 38.411 50.367 1.00 46.74 O HETATM 3448 O HOH B2004 23.951 37.104 49.758 1.00 47.83 O HETATM 3449 O HOH B2005 15.690 34.245 49.648 1.00 35.46 O HETATM 3450 O HOH B2006 22.958 36.875 55.070 1.00 48.10 O HETATM 3451 O HOH B2007 16.463 31.657 48.436 1.00 35.64 O HETATM 3452 O HOH B2008 22.419 33.747 52.498 1.00 40.80 O HETATM 3453 O HOH B2009 14.979 30.691 50.686 1.00 30.91 O HETATM 3454 O HOH B2010 14.538 27.605 53.934 1.00 29.28 O HETATM 3455 O HOH B2011 20.511 30.149 55.436 1.00 39.22 O HETATM 3456 O HOH B2012 16.466 31.948 56.064 1.00 50.31 O HETATM 3457 O HOH B2013 23.145 30.920 47.207 1.00 23.36 O HETATM 3458 O HOH B2014 25.047 24.989 54.143 1.00 37.98 O HETATM 3459 O HOH B2015 22.178 19.159 55.145 1.00 51.19 O HETATM 3460 O HOH B2016 24.441 30.983 49.673 1.00 29.21 O HETATM 3461 O HOH B2017 18.793 20.913 53.729 1.00 23.50 O HETATM 3462 O HOH B2018 30.660 23.783 42.977 1.00 45.75 O HETATM 3463 O HOH B2019 28.146 26.432 53.319 1.00 52.10 O HETATM 3464 O HOH B2020 24.581 17.230 50.484 1.00 44.10 O HETATM 3465 O HOH B2021 27.522 22.403 46.197 1.00 23.04 O HETATM 3466 O HOH B2022 30.365 22.441 45.234 1.00 41.96 O HETATM 3467 O HOH B2023 32.968 24.082 43.115 1.00 41.68 O HETATM 3468 O HOH B2024 14.826 33.298 51.968 1.00 34.28 O HETATM 3469 O HOH B2025 23.505 31.404 52.176 1.00 29.24 O HETATM 3470 O HOH B2026 22.392 29.181 53.574 1.00 38.03 O HETATM 3471 O HOH B2027 23.906 27.762 54.985 1.00 36.89 O HETATM 3472 O HOH B2028 27.085 15.408 49.358 1.00 48.37 O HETATM 3473 O HOH C2001 24.053 31.935 38.771 1.00 24.50 O HETATM 3474 O HOH C2002 22.543 36.499 37.840 1.00 34.64 O HETATM 3475 O HOH C2003 19.334 39.141 40.573 1.00 42.56 O HETATM 3476 O HOH C2004 36.510 32.698 45.634 1.00 55.71 O HETATM 3477 O HOH C2005 28.989 35.038 43.644 1.00 48.30 O HETATM 3478 O HOH C2006 30.240 26.459 41.913 1.00 39.84 O HETATM 3479 O HOH C2007 26.318 32.038 42.259 1.00 36.32 O HETATM 3480 O HOH C2008 26.607 29.313 35.906 1.00 28.72 O HETATM 3481 O HOH C2009 29.591 33.647 37.111 1.00 38.13 O HETATM 3482 O HOH C2010 26.912 31.798 39.120 1.00 39.92 O HETATM 3483 O HOH C2011 28.980 28.933 34.486 1.00 36.82 O HETATM 3484 O HOH C2012 24.653 32.010 44.901 1.00 38.45 O HETATM 3485 O HOH C2013 18.775 21.728 27.684 1.00 16.90 O HETATM 3486 O HOH C2014 28.905 21.397 36.994 1.00 25.93 O HETATM 3487 O HOH C2015 30.146 24.398 35.183 1.00 36.30 O HETATM 3488 O HOH C2016 22.265 31.543 36.720 1.00 17.39 O HETATM 3489 O HOH C2017 24.213 29.040 34.961 1.00 18.50 O HETATM 3490 O HOH C2018 22.658 34.055 39.644 1.00 31.36 O HETATM 3491 O HOH C2019 13.131 33.764 38.223 1.00 28.35 O HETATM 3492 O HOH C2020 15.424 33.301 35.492 1.00 25.90 O HETATM 3493 O HOH C2021 19.793 36.521 40.489 1.00 31.43 O HETATM 3494 O HOH C2022 8.470 33.078 38.916 1.00 42.93 O HETATM 3495 O HOH C2023 6.711 30.407 44.821 1.00 33.96 O HETATM 3496 O HOH C2024 14.454 37.861 39.410 1.00 40.96 O HETATM 3497 O HOH C2025 8.235 41.353 43.363 1.00 42.52 O CONECT 1135 3098 CONECT 1853 3097 CONECT 1867 3097 CONECT 1886 3097 CONECT 2939 2952 CONECT 2952 2939 2953 2954 2955 CONECT 2953 2952 CONECT 2954 2952 CONECT 2955 2952 2956 CONECT 2956 2955 2957 CONECT 2957 2956 2958 2959 CONECT 2958 2957 2962 CONECT 2959 2957 2960 2961 CONECT 2960 2959 2975 CONECT 2961 2959 2962 CONECT 2962 2958 2961 2963 CONECT 2963 2962 2964 2973 CONECT 2964 2963 2965 2974 CONECT 2965 2964 2966 CONECT 2966 2965 2967 2973 CONECT 2967 2966 2968 2969 CONECT 2968 2967 CONECT 2969 2967 2970 CONECT 2970 2969 2971 2972 CONECT 2971 2970 CONECT 2972 2970 2973 CONECT 2973 2963 2966 2972 CONECT 2974 2964 CONECT 2975 2960 CONECT 2977 3098 CONECT 3019 3097 CONECT 3097 1853 1867 1886 3019 CONECT 3098 1135 2977 3473 CONECT 3473 3098 MASTER 582 0 3 17 7 0 2 6 3494 3 34 32 END
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Related entries of code: 2xhi
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
1n3c
RCSB PDB
PDBbind
15aa, >1N3C_2|Chain... *
2noe
RCSB PDB
PDBbind
15aa, >2NOE_2|Chain... at 100%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
2xhi
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
human hOgg1 Triple Mutant N-GLYCOSYLASE/DNA LYASE (K249C C253K D268N)
Ligand Name
8oxoG-Containing DNA
EC.Number
E.C.3.2.2.-
Resolution
1.55(Å)
Affinity (Kd/Ki/IC50)
Kd=0.17nM
Release Year
2011
Protein/NA Sequence
Check fasta file
Primary Reference
(2011) Structure Vol. 19: pp. 117-127
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
O15527
Entrez Gene ID
NCBI Entrez Gene ID:
4968
ASD
Information of known allosteric effects of PDB entries
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