Browse entries in the PDBbind-CN Database

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Related entries of code: 3fzs
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3et7RCSB PDB    PDBbind277aa, >3ET7_1|Chain... at 100%
3fzrRCSB PDB    PDBbind277aa, >3FZR_1|Chain... at 100%
3fztRCSB PDB    PDBbind277aa, >3FZT_1|Chain... at 100%
3h3cRCSB PDB    PDBbind277aa, >3H3C_1|Chain... at 100%
4h1jRCSB PDB    PDBbind293aa, >4H1J_1|Chain... *
4h1mRCSB PDB    PDBbind293aa, >4H1M_1|Chain... at 100%
5to8RCSB PDB    PDBbind282aa, >5TO8_1|Chain... at 98%
5tobRCSB PDB    PDBbind282aa, >5TOB_1|Chain... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
1kv2RCSB PDB    PDBbindB96
3npcRCSB PDB    PDBbindB96
Entry Information
PDB ID3fzs
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameProtein tyrosine kinase 2 beta
Ligand NameB96
EC.Number E.C.2.7.10.2
Resolution 1.75(Å)
Affinity (Kd/Ki/IC50)IC50=1.5uM
Release Year2009
Protein/NA SequenceCheck fasta file
Primary Reference (2009) J.Biol.Chem. Vol. 284: pp. 13193-13201
Ligand Properties
Formula C31H38N5O3
Molecular Weight 528.665
Exact Mass 528.297
No. of atoms 77
No. of bonds 81
Polar Surface Area 81.85
LOGP Value 5.74      (Computed with XLOGP3)
6.28      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 10
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q14289  
Entrez Gene IDNCBI Entrez Gene ID: 2185  
ASDInformation of known allosteric effects of PDB entries
 
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