Browse entries in the PDBbind-CN Database

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Related entries of code: 4g2w
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1udtRCSB PDB    PDBbind324aa, >1UDT_1|Chain... at 100%
1uduRCSB PDB    PDBbind324aa, >1UDU_1|Chains... at 100%
1uhoRCSB PDB    PDBbind324aa, >1UHO_1|Chain... at 100%
2chmRCSB PDB    PDBbind326aa, >2CHM_1|Chain... at 94%
2h42RCSB PDB    PDBbind326aa, >2H42_1|Chains... at 100%
2h44RCSB PDB    PDBbind326aa, >2H44_1|Chain... at 100%
2k31RCSB PDB    PDBbind176aa, >2K31_1|Chain... at 92%
3bjcRCSB PDB    PDBbind878aa, >3BJC_1|Chain... *
3hc8RCSB PDB    PDBbind324aa, >3HC8_1|Chain... at 94%
3hdzRCSB PDB    PDBbind324aa, >3HDZ_1|Chain... at 94%
3jwqRCSB PDB    PDBbind330aa, >3JWQ_1|Chains... at 92%
3shyRCSB PDB    PDBbind347aa, >3SHY_1|Chain... at 93%
3shzRCSB PDB    PDBbind347aa, >3SHZ_1|Chain... at 93%
3sieRCSB PDB    PDBbind347aa, >3SIE_1|Chains... at 93%
3tgeRCSB PDB    PDBbind326aa, >3TGE_1|Chain... at 94%
4g2yRCSB PDB    PDBbind347aa, >4G2Y_1|Chain... at 93%
4i9zRCSB PDB    PDBbind347aa, >4I9Z_1|Chain... at 93%
4ia0RCSB PDB    PDBbind347aa, >4IA0_1|Chain... at 93%
4md6RCSB PDB    PDBbind326aa, >4MD6_1|Chain... at 100%
4oewRCSB PDB    PDBbind347aa, >4OEW_1|Chain... at 93%
4oexRCSB PDB    PDBbind347aa, >4OEX_1|Chain... at 93%
5zz2RCSB PDB    PDBbind326aa, >5ZZ2_1|Chain... at 100%
6acbRCSB PDB    PDBbind326aa, >6ACB_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID4g2w
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NamecGMP-specific 3',5'-cyclic phosphodiesterase
Ligand NameNI0
EC.Number E.C.3.1.4.35
Resolution 2.28(Å)
Affinity (Kd/Ki/IC50)IC50=1.6nM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2012) J.Med.Chem. Vol. 55: pp. 10540-10550
Ligand Properties
Formula C22H33N4O4S
Molecular Weight 449.587
Exact Mass 449.222
No. of atoms 64
No. of bonds 66
Polar Surface Area 105.44
LOGP Value 3.30      (Computed with XLOGP3)
3.87      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O76074  
Entrez Gene IDNCBI Entrez Gene ID: 8654  
ASDInformation of known allosteric effects of PDB entries

 
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