Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 4ipf
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1ttvRCSB PDB    PDBbind107aa, >1TTV_1|Chain... *
4j3eRCSB PDB    PDBbind86aa, >4J3E_1|Chain... at 98%
4j74RCSB PDB    PDBbind86aa, >4J74_1|Chain... at 98%
4j7dRCSB PDB    PDBbind86aa, >4J7D_1|Chain... at 98%
4j7eRCSB PDB    PDBbind86aa, >4J7E_1|Chain... at 98%
4jrgRCSB PDB    PDBbind85aa, >4JRG_1|Chains... at 100%
4jscRCSB PDB    PDBbind86aa, >4JSC_1|Chains... at 98%
4lwtRCSB PDB    PDBbind86aa, >4LWT_1|Chain... at 98%
4lwuRCSB PDB    PDBbind85aa, >4LWU_1|Chain... at 100%
4lwvRCSB PDB    PDBbind85aa, >4LWV_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4ipf
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameE3 ubiquitin-protein ligase Mdm2 (I50L, P92H, L95I mutation)
Ligand Name1F0
EC.Number E.C.6.3.2
Resolution 1.7(Å)
Affinity (Kd/Ki/IC50)IC50=18nM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) Cancer Res. Vol. 73: pp. 2587-2597
Ligand Properties
Formula C38H49Cl2N4O4S
Molecular Weight 728.791
Exact Mass 727.285
No. of atoms 98
No. of bonds 102
Polar Surface Area 92.1
LOGP Value 7.27      (Computed with XLOGP3)
8.30      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 12
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P56273  
Entrez Gene IDNo matched NCBI Entrez Gene ID found!
ASDInformation of known allosteric effects of PDB entries
 
This site has been visited times since Nov 2007.


Copyright ©2007-2025    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com