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Related entries of code: 4j52
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2ou7RCSB PDB    PDBbind335aa, >2OU7_1|Chain... at 99%
2owbRCSB PDB    PDBbind335aa, >2OWB_1|Chain... at 99%
2rkuRCSB PDB    PDBbind294aa, >2RKU_1|Chain... at 100%
2yacRCSB PDB    PDBbind311aa, >2YAC_1|Chain... at 99%
3fc2RCSB PDB    PDBbind335aa, >3FC2_1|Chain... at 99%
3kb7RCSB PDB    PDBbind311aa, >3KB7_1|Chain... at 99%
3thbRCSB PDB    PDBbind333aa, >3THB_1|Chain... at 100%
4a4lRCSB PDB    PDBbind311aa, >4A4L_1|Chain... at 99%
4a4oRCSB PDB    PDBbind311aa, >4A4O_1|Chain... at 99%
4j53RCSB PDB    PDBbind293aa, >4J53_1|Chain... at 100%
5ta6RCSB PDB    PDBbind358aa, >5TA6_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID4j52
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameSerine/threonine-protein kinase PLK1 (T210V mutation)
Ligand Name1J3
EC.Number E.C.
Resolution 2.3(Å)
Affinity (Kd/Ki/IC50)IC50=3nM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) Bioorg.Med.Chem.Lett. Vol. 23: pp. 3662-3666
Ligand Properties
Formula C28H39FN8O3
Molecular Weight 554.659
Exact Mass 554.313
No. of atoms 79
No. of bonds 83
Polar Surface Area 108.57
LOGP Value 3.27      (Computed with XLOGP3)
3.64      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 11
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P53350  
Entrez Gene IDNCBI Entrez Gene ID: 5347  
ASDInformation of known allosteric effects of PDB entries

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