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Related entries of code: 5fv7
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3uvuRCSB PDB    PDBbind19aa, >3UVU_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5fv7
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namestructure-specific nuclease human flap endonuclease-1 (hFEN1-336delta)
Ligand NameR3Z
EC.Number E.C.3.1
Resolution 2.84(Å)
Affinity (Kd/Ki/IC50)Kd=182nM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2016) Nat.Chem.Biol. Vol. 12: pp. 815-821
Ligand Properties
Formula C15H12N2O5S
Molecular Weight 332.331
Exact Mass 332.047
No. of atoms 35
No. of bonds 38
Polar Surface Area 110.93
LOGP Value 1.81      (Computed with XLOGP3)
1.30      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 3
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P39748  
Entrez Gene IDNCBI Entrez Gene ID: 2237  
ASDInformation of known allosteric effects of PDB entries

 
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