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Related entries of code: 5u4x
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2y1wRCSB PDB    PDBbind348aa, >2Y1W_1|Chains... at 100%
2y1xRCSB PDB    PDBbind348aa, >2Y1X_1|Chains... at 100%
5k8vRCSB PDB    PDBbind361aa, >5K8V_1|Chains... *
5lgsRCSB PDB    PDBbind361aa, >5LGS_1|Chains... at 100%
6arjRCSB PDB    PDBbind349aa, >6ARJ_1|Chains... at 99%
6arvRCSB PDB    PDBbind349aa, >6ARV_1|Chains... at 99%
6izqRCSB PDB    PDBbind333aa, >6IZQ_1|Chains... at 100%
5tbjRCSB PDB    PDBbind361aa, >5TBJ_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5u4x
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameHistone-arginine methyltransferase CARM1
Ligand Name7VM
EC.Number E.C.2.1.1.319
Resolution 1.88(Å)
Affinity (Kd/Ki/IC50)Kd=7.1nM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2018) Oncotarget Vol. 9: pp. 18480-18493
Ligand Properties
Formula C28H36N4O2
Molecular Weight 460.611
Exact Mass 460.284
No. of atoms 70
No. of bonds 73
Polar Surface Area 63.48
LOGP Value 3.52      (Computed with XLOGP3)
3.67      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 10
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q86X55  
Entrez Gene IDNCBI Entrez Gene ID: 10498  
ASDInformation of known allosteric effects of PDB entries

 
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