Browse entries in the PDBbind-CN Database

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Related entries of code: 5ut4
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4fvqRCSB PDB    PDBbind289aa, >4FVQ_1|Chain... *
4fvrRCSB PDB    PDBbind289aa, >4FVR_1|Chain... at 99%
5uszRCSB PDB    PDBbind289aa, >5USZ_1|Chain... at 100%
5ut0RCSB PDB    PDBbind289aa, >5UT0_1|Chain... at 100%
5ut6RCSB PDB    PDBbind289aa, >5UT6_1|Chain... at 100%
6g3cRCSB PDB    PDBbind272aa, >6G3C_1|Chains... at 99%
5winRCSB PDB    PDBbind277aa, >5WIN_1|Chain... at 100%
5wikRCSB PDB    PDBbind277aa, >5WIK_1|Chain... at 100%
5wijRCSB PDB    PDBbind277aa, >5WIJ_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3krrRCSB PDB    PDBbindDQX

Entry Information
PDB ID5ut4
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameTyrosine-protein kinase JAK2
Ligand NameDQX
EC.Number E.C.-.-.-.-
Resolution 2(Å)
Affinity (Kd/Ki/IC50)Kd=42uM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) ACS Med Chem Lett Vol. 8: pp. 614-617
Ligand Properties
Formula C27H30F2N6O
Molecular Weight 492.564
Exact Mass 492.245
No. of atoms 66
No. of bonds 71
Polar Surface Area 73.88
LOGP Value 2.50      (Computed with XLOGP3)
4.89      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 6
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O60674  
Entrez Gene IDNCBI Entrez Gene ID: 3717  
ASDInformation of known allosteric effects of PDB entries

 
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