Browse entries in the PDBbind-CN Database

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Related entries of code: 6dz3
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1k27RCSB PDB    PDBbind283aa, >1K27_1|Chain... at 100%
6dz2RCSB PDB    PDBbind297aa, >6DZ2_1|Chains... at 100%
6dz0RCSB PDB    PDBbind297aa, >6DZ0_1|Chain... at 100%
6dyzRCSB PDB    PDBbind297aa, >6DYZ_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
6dyyRCSB PDB    PDBbindOS6
Entry Information
PDB ID6dz3
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameS-methyl-5'-thioadenosine phosphorylase
Ligand NameOS6
EC.Number E.C.2.4.2.28
Resolution 1.91(Å)
Affinity (Kd/Ki/IC50)Kd=1.3nM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) J. Med. Chem. Vol. 62: pp. 3286-3296
Ligand Properties
Formula C21H33N8OS
Molecular Weight 445.605
Exact Mass 445.250
No. of atoms 64
No. of bonds 67
Polar Surface Area 148.27
LOGP Value 1.27      (Computed with XLOGP3)
2.82      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 12
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q13126  
Entrez Gene IDNCBI Entrez Gene ID: 4507  
ASDInformation of known allosteric effects of PDB entries
 
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