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Related entries of code: 1y6b
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1y6aRCSB PDB    PDBbind366aa, >1Y6A_1|Chain... at 100%
3vheRCSB PDB    PDBbind359aa, >3VHE_1|Chain... at 100%
3vhkRCSB PDB    PDBbind368aa, >3VHK_1|Chain... *
3vidRCSB PDB    PDBbind356aa, >3VID_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID1y6b
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namevascular endothelial growth factor receptor 2
Ligand NameAAX
EC.Number E.C.
Resolution 2.1(Å)
Affinity (Kd/Ki/IC50)IC50=38nM
Release Year2005
Protein/NA SequenceCheck fasta file
Primary Reference J.Med.Chem. v48 pp. 1610-9, 2005
Ligand Properties
Formula C25H24N4O4S
Molecular Weight 476.547
Exact Mass 476.152
No. of atoms 58
No. of bonds 62
Polar Surface Area 114.73
LOGP Value 4.11      (Computed with XLOGP3)
6.39      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P35968  
Entrez Gene IDNCBI Entrez Gene ID: 3791  
ASDInformation of known allosteric effects of PDB entries

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