Browse entries in the PDBbind-CN Database

Display Options: Structure:  

Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 3krj
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2i0vRCSB PDB    PDBbind335aa, >2I0V_1|Chain... at 91%
2i0yRCSB PDB    PDBbind335aa, >2I0Y_1|Chain... at 91%
2i1mRCSB PDB    PDBbind333aa, >2I1M_1|Chain... at 90%
3beaRCSB PDB    PDBbind333aa, >3BEA_1|Chain... at 91%
3dpkRCSB PDB    PDBbind335aa, >3DPK_1|Chain... at 91%
3krlRCSB PDB    PDBbind335aa, >3KRL_1|Chain... at 91%
3lcdRCSB PDB    PDBbind329aa, >3LCD_1|Chain... at 95%
3lcoRCSB PDB    PDBbind324aa, >3LCO_1|Chain... at 98%
4hw7RCSB PDB    PDBbind343aa, >4HW7_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID3krj
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMacrophage colony-stimulating factor 1 receptor, Basic fibroblast growth factor receptor 1, FMS
Ligand NameKRJ
EC.Number E.C.
Resolution 2.1(Å)
Affinity (Kd/Ki/IC50)IC50=1.1nM
Release Year2010
Protein/NA SequenceCheck fasta file
Primary Reference (2011) J.Med.Chem. Vol. 54: pp. 7860-7883
Ligand Properties
Formula C22H26N5O
Molecular Weight 376.475
Exact Mass 376.214
No. of atoms 54
No. of bonds 57
Polar Surface Area 98.18
LOGP Value 3.11      (Computed with XLOGP3)
4.57      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P11362  P07333  
Entrez Gene IDNCBI Entrez Gene ID: 2260  1436  
ASDInformation of known allosteric effects of PDB entries

This site has been visited times since Nov 2007.

Copyright ©2007-2024    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝e湪鐢宠涓

Technical Support锛堟妧鏈敮鎸侊級: