Browse entries in the PDBbind-CN Database

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Related entries of code: 3krl
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2i0vRCSB PDB    PDBbind335aa, >2I0V_1|Chain... at 91%
2i0yRCSB PDB    PDBbind335aa, >2I0Y_1|Chain... at 91%
2i1mRCSB PDB    PDBbind333aa, >2I1M_1|Chain... at 90%
3beaRCSB PDB    PDBbind333aa, >3BEA_1|Chain... at 91%
3dpkRCSB PDB    PDBbind335aa, >3DPK_1|Chain... at 91%
3krjRCSB PDB    PDBbind335aa, >3KRJ_1|Chain... at 91%
3lcdRCSB PDB    PDBbind329aa, >3LCD_1|Chain... at 95%
3lcoRCSB PDB    PDBbind324aa, >3LCO_1|Chain... at 98%
4hw7RCSB PDB    PDBbind343aa, >4HW7_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID3krl
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMacrophage colony-stimulating factor 1 receptor, Basic fibroblast growth factor receptor 1, FMS
Ligand NameKRL
EC.Number E.C.2.7.10.1
Resolution 2.4(Å)
Affinity (Kd/Ki/IC50)IC50=0.8nM
Release Year2010
Protein/NA SequenceCheck fasta file
Primary Reference (2011) J.Med.Chem. Vol. 54: pp. 7860-7883
Ligand Properties
Formula C22H28N5O2
Molecular Weight 394.490
Exact Mass 394.224
No. of atoms 57
No. of bonds 60
Polar Surface Area 76.95
LOGP Value 3.11      (Computed with XLOGP3)
3.50      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P11362  P07333  
Entrez Gene IDNCBI Entrez Gene ID: 2260  1436  
ASDInformation of known allosteric effects of PDB entries

 
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