Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 5eym
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3e8nRCSB PDB    PDBbind341aa, >3E8N_1|Chain... at 97%
3eqbRCSB PDB    PDBbind333aa, >3EQB_1|Chain... at 99%
3mblRCSB PDB    PDBbind328aa, >3MBL_1|Chain... at 97%
3pp1RCSB PDB    PDBbind328aa, >3PP1_1|Chain... at 97%
3v01RCSB PDB    PDBbind341aa, >3V01_1|Chain... at 97%
3v04RCSB PDB    PDBbind341aa, >3V04_1|Chain... at 97%
3zlsRCSB PDB    PDBbind348aa, >3ZLS_1|Chain... at 98%
3zlwRCSB PDB    PDBbind348aa, >3ZLW_1|Chain... at 98%
3zlxRCSB PDB    PDBbind348aa, >3ZLX_1|Chain... at 98%
3zlyRCSB PDB    PDBbind348aa, >3ZLY_1|Chain... at 98%
3zm4RCSB PDB    PDBbind348aa, >3ZM4_1|Chain... at 98%
4arkRCSB PDB    PDBbind341aa, >4ARK_1|Chain... at 97%
4lmnRCSB PDB    PDBbind341aa, >4LMN_1|Chain... at 97%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
5eykRCSB PDB    PDBbind5U5

Entry Information
PDB ID5eym
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namehuman MEK1
Ligand Name5U5
EC.Number E.C.2.7.12.2
Resolution 2.7(Å)
Affinity (Kd/Ki/IC50)IC50=25nM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2016) Mol.Cancer Ther. Vol. 15: pp. 1-28
Ligand Properties
Formula C29H29N4O2
Molecular Weight 465.566
Exact Mass 465.229
No. of atoms 64
No. of bonds 67
Polar Surface Area 75
LOGP Value 4.30      (Computed with XLOGP3)
3.20      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q02750  
Entrez Gene IDNCBI Entrez Gene ID: 5604  
ASDInformation of known allosteric effects of PDB entries

 
This site has been visited times since Nov 2007.


Copyright ©2007-2024    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝e湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com