Browse entries in the PDBbind-CN Database

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Related entries of code: 6c0t
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
No similar entries are found!
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
6c0uRCSB PDB    PDBbindEE4

Entry Information
PDB ID6c0t
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NamecGMP-dependent protein kinase 1
Ligand NameEE4
EC.Number E.C.2.7.11.12
Resolution 1.98(Å)
Affinity (Kd/Ki/IC50)IC50=43.1nM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) J. Biol. Chem. Vol. 293: pp. 10985-10992
Ligand Properties
Formula C30H28FN5O5
Molecular Weight 557.572
Exact Mass 557.207
No. of atoms 69
No. of bonds 73
Polar Surface Area 134.77
LOGP Value 3.40      (Computed with XLOGP3)
3.93      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 12
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q13976  
Entrez Gene IDNCBI Entrez Gene ID: 5592  
ASDInformation of known allosteric effects of PDB entries

 
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