Browse entries in the PDBbind-CN Database

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Related entries of code: 6cw8
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5eeiRCSB PDB    PDBbind364aa, >5EEI_1|Chains... *
5eekRCSB PDB    PDBbind364aa, >5EEK_1|Chain... at 100%
5eenRCSB PDB    PDBbind364aa, >5EEN_1|Chains... at 100%
5ef7RCSB PDB    PDBbind364aa, >5EF7_1|Chains... at 100%
5ef8RCSB PDB    PDBbind364aa, >5EF8_1|Chains... at 100%
5efbRCSB PDB    PDBbind364aa, >5EFB_1|Chain... at 100%
5efhRCSB PDB    PDBbind364aa, >5EFH_1|Chains... at 100%
5efjRCSB PDB    PDBbind364aa, >5EFJ_1|Chain... at 100%
6cgpRCSB PDB    PDBbind364aa, >6CGP_1|Chain... at 100%
6cspRCSB PDB    PDBbind364aa, >6CSP_1|Chains... at 100%
6csqRCSB PDB    PDBbind364aa, >6CSQ_1|Chains... at 100%
6csrRCSB PDB    PDBbind364aa, >6CSR_1|Chains... at 100%
6cssRCSB PDB    PDBbind364aa, >6CSS_1|Chains... at 100%
6dvlRCSB PDB    PDBbind364aa, >6DVL_1|Chains... at 100%
6dvmRCSB PDB    PDBbind364aa, >6DVM_1|Chains... at 100%
6dvnRCSB PDB    PDBbind364aa, >6DVN_1|Chains... at 100%
6dvoRCSB PDB    PDBbind364aa, >6DVO_1|Chain... at 100%
6mr5RCSB PDB    PDBbind364aa, >6MR5_1|Chains... at 100%
6r0kRCSB PDB    PDBbind359aa, >6R0K_1|Chain... at 100%
5w5kRCSB PDB    PDBbind364aa, >5W5K_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID6cw8
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameHdac6 protein
Ligand NameFGY
EC.Number E.C.-.-.-.-
Resolution 1.9(Å)
Affinity (Kd/Ki/IC50)IC50=0.27uM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) J. Med. Chem. Vol. 61: pp. 10299-10309
Ligand Properties
Formula C27H35N5O6
Molecular Weight 525.597
Exact Mass 525.259
No. of atoms 73
No. of bonds 74
Polar Surface Area 165.73
LOGP Value 1.58      (Computed with XLOGP3)
3.23      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 6
No. of Hydrogen Bond Acceptors: 6
No. of Rotatable Bonds: 18
No. of Nitrogen and Oxygen Atoms: 11
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): F8W4B7  
Entrez Gene IDNCBI Entrez Gene ID: 565482  
ASDInformation of known allosteric effects of PDB entries

 
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