Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 6gfy
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3zrcRCSB PDB    PDBbind97aa, >3ZRC_2|Chains... *
3ztcRCSB PDB    PDBbind97aa, >3ZTC_2|Chains... at 100%
3ztdRCSB PDB    PDBbind97aa, >3ZTD_2|Chains... at 100%
4awjRCSB PDB    PDBbind97aa, >4AWJ_2|Chains... at 100%
4b95RCSB PDB    PDBbind97aa, >4B95_2|Chains... at 100%
4b9kRCSB PDB    PDBbind97aa, >4B9K_4|Chain... at 100%
4bksRCSB PDB    PDBbind97aa, >4BKS_2|Chains... at 100%
4bktRCSB PDB    PDBbind97aa, >4BKT_2|Chains... at 100%
4jghRCSB PDB    PDBbind96aa, >4JGH_3|Chain... at 98%
4w9cRCSB PDB    PDBbind97aa, >4W9C_2|Chains... at 100%
4w9dRCSB PDB    PDBbind97aa, >4W9D_2|Chains... at 100%
4w9eRCSB PDB    PDBbind97aa, >4W9E_2|Chains... at 100%
4w9fRCSB PDB    PDBbind97aa, >4W9F_2|Chains... at 100%
4w9gRCSB PDB    PDBbind97aa, >4W9G_2|Chains... at 100%
4w9hRCSB PDB    PDBbind97aa, >4W9H_2|Chains... at 100%
4w9iRCSB PDB    PDBbind97aa, >4W9I_2|Chains... at 100%
4w9jRCSB PDB    PDBbind97aa, >4W9J_2|Chains... at 100%
4w9kRCSB PDB    PDBbind97aa, >4W9K_2|Chains... at 100%
4w9lRCSB PDB    PDBbind97aa, >4W9L_2|Chains... at 100%
5lliRCSB PDB    PDBbind97aa, >5LLI_2|Chains... at 100%
5n4wRCSB PDB    PDBbind97aa, >5N4W_5|Chain... at 100%
5nvvRCSB PDB    PDBbind97aa, >5NVV_2|Chains... at 100%
5nvwRCSB PDB    PDBbind97aa, >5NVW_2|Chains... at 100%
5nvxRCSB PDB    PDBbind97aa, >5NVX_2|Chains... at 100%
5nvyRCSB PDB    PDBbind97aa, >5NVY_2|Chains... at 100%
5nvzRCSB PDB    PDBbind97aa, >5NVZ_2|Chains... at 100%
5nw0RCSB PDB    PDBbind97aa, >5NW0_2|Chains... at 100%
5nw1RCSB PDB    PDBbind97aa, >5NW1_2|Chains... at 100%
5nw2RCSB PDB    PDBbind97aa, >5NW2_2|Chains... at 100%
5t35RCSB PDB    PDBbind97aa, >5T35_3|Chains... at 100%
6fmiRCSB PDB    PDBbind97aa, >6FMI_2|Chains... at 100%
6fmjRCSB PDB    PDBbind97aa, >6FMJ_2|Chains... at 100%
6fmkRCSB PDB    PDBbind97aa, >6FMK_2|Chains... at 100%
6gfzRCSB PDB    PDBbind97aa, >6GFZ_2|Chains... at 100%
6gmqRCSB PDB    PDBbind97aa, >6GMQ_4|Chains... at 100%
6gmxRCSB PDB    PDBbind97aa, >6GMX_2|Chains... at 100%
6hr2RCSB PDB    PDBbind97aa, >6HR2_3|Chains... at 100%
6hayRCSB PDB    PDBbind97aa, >6HAY_3|Chains... at 100%
6haxRCSB PDB    PDBbind97aa, >6HAX_3|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID6gfy
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NamepVHL:EloB:EloC
Ligand NameEXH
EC.Number E.C.-.-.-.-
Resolution 2.7(Å)
Affinity (Kd/Ki/IC50)Kd=244nM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) J. Am. Chem. Soc. Vol. 140: pp. 9299-9313
Ligand Properties
Formula C24H31FN4O4S
Molecular Weight 490.591
Exact Mass 490.205
No. of atoms 65
No. of bonds 67
Polar Surface Area 139.87
LOGP Value 2.36      (Computed with XLOGP3)
2.92      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 11
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P40337  Q15369  Q15370  
Entrez Gene IDNCBI Entrez Gene ID: 7428  6921  6923  
ASDInformation of known allosteric effects of PDB entries

 
This site has been visited times since Nov 2007.


Copyright ©2007-2024    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝e湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com