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Related entries of code: 5k8v
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2y1wRCSB PDB    PDBbind348aa, >2Y1W_1|Chains... at 100%
2y1xRCSB PDB    PDBbind348aa, >2Y1X_1|Chains... at 100%
5lgsRCSB PDB    PDBbind361aa, >5LGS_1|Chains... at 100%
5u4xRCSB PDB    PDBbind341aa, >5U4X_1|Chains... at 100%
6arjRCSB PDB    PDBbind349aa, >6ARJ_1|Chains... at 99%
6arvRCSB PDB    PDBbind349aa, >6ARV_1|Chains... at 99%
6izqRCSB PDB    PDBbind333aa, >6IZQ_1|Chains... at 100%
5tbjRCSB PDB    PDBbind361aa, >5TBJ_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5k8v
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMus musculus Protein Arginine Methyltransferase 4 (CARM1 130-487)
Ligand Name6RE
EC.Number E.C.2.1.1.319
Resolution 2.25(Å)
Affinity (Kd/Ki/IC50)IC50=460nM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2017) FEBS J. Vol. 284: pp. 77-96
Ligand Properties
Formula C12H19N8O3
Molecular Weight 323.331
Exact Mass 323.158
No. of atoms 42
No. of bonds 44
Polar Surface Area 185.32
LOGP Value -0.86      (Computed with XLOGP3)
-2.25      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 11
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q9WVG6  
Entrez Gene IDNCBI Entrez Gene ID: 59035  
ASDInformation of known allosteric effects of PDB entries

 
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